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An aerosol precursor containing Chuanbei Xueli Plaster medicinal active ingredients and a method for dispersing it into nano-scale droplets

A medicinal ingredient, the technology of Sydney ointment, which is applied in the field of aerosol precursors, can solve the problems of high cost of propellants, poor drug atomization effect, and high injection pressure, so as to improve the effective utilization rate, shorten the action time, Applicable to a wide range of groups

Active Publication Date: 2016-08-24
CHINA TOBACCO YUNNAN IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The representative patent for pressurized atomization of traditional Chinese medicine compound preparations is CN102949573A, in which an 80-100bar propellant such as trichlorofluoromethane, dichlorodifluoromethane or dichlorotetrafluoroethane is used to atomize the liquid medicine to To obtain micron-sized mist droplets, the above-mentioned injection pressure is too high, the airtightness of the propellant container tank is strict, the production cost is high, and the propellant itself is also expensive
In addition, with the increase of the amount of medicine used, the pressure inside the tank decreases continuously, and the drug atomization effect gradually becomes worse; moreover, such tanks can only be used once for consumers, increasing usage cost

Method used

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Examples

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Effect test

Embodiment 1

[0032] An aerosol precursor comprising the active ingredient of Chuanbei Xueli plaster, which comprises glycerin, propylene glycol, 1,3-butanediol, flavoring substances and Chuanbei Xueli plaster extract, and their mass ratio is glycerin Alcohol: Propylene Glycol: Chuanbei Xueli Extract = 40:20:1.

[0033] Wherein said Chuanbei Xueli Extract is obtained by the method comprising the following steps:

[0034] (1) Impurity removal: Dissolve Chuanbei Xueli Cream in edible grade ethanol, filter, remove insoluble impurities, and obtain the ethanol solution of Chuanbei Xueli Cream;

[0035] (2) Decolorization: the ethanol solution of the Chuanbei Xueli paste obtained in step (1) is passed through the first macroporous resin chromatographic column, and is eluted with ethanol-water solution of 40% by volume to remove the pigment component wherein; The model of the first macroporous resin chromatographic column is preferably MCIGEL CHP 20P (75-150 μm).

[0036] (3) sugar removal: the et...

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PUM

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Abstract

The invention relates to an aerosol precursor containing medical components of Chuanbei Xueli Extract. The aerosol precursor comprises glycerine, propanediol, 1,3-butanediol, an aromatic substance and Chuanbei Xueli Extract of which the mass ratio is as follows: glycerine: propanediol: 1,3-butanediol: aromatic substance: Chuanbei Xueli Extract= (40-45): (20-25): (0-10): (0-10): (1-10). The invention also relates to a method for dispersing medical components in Chuanbei Xueli Extract into nanoscale fog drops, as well as an aerosol containing nanoscale fog drops. As the aerosol precursor contains medical components of Chuanbei Xueli Extract, when the aerosol precursor is placed in an electronic cigarette smoking set including an electric heating device to be heated, nanoscale fog drops can be obtained to bring more convenience for the medical components to be absorbed by a human body.

Description

technical field [0001] The invention relates to an aerosol precursor, in particular to an aerosol precursor containing medicinal components of Chuanbei Xueli Plaster and a method for dispersing it into nano-scale droplets. Background technique [0002] The main ingredients of Chuanbei Xueli Cream are Liqing Cream, Chuan Fritillaria, Ophiopogon japonicus, Lily, and Coltsfoot. The supplementary material is sucrose, which is brownish-yellow thick and semi-fluid, sweet in taste, and has the effects of moistening the lungs and relieving cough, promoting body fluid and relieving throat. Usually, the administration method of Chuanbei Xueli Cream is oral administration. On the one hand, the drug effect is slow; on the one hand, it will cause the irritation of the drug to the stomach; Drug utilization decreased. [0003] Aerosols generally refer to preparations that produce droplets when heated or pressurized. In the field of medicine and pharmacy, aerosols refer to preparations t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A24F47/00A24B15/16
CPCA61K36/8966A61K36/8967A61K36/8968A61K47/10A61M11/005A61M11/042A24B15/16A61K9/0043A61K36/28A61K36/73A61K9/12A61K2236/53A61K2236/55A61K2236/51A61K2300/00
Inventor 赵伟杨继杨柳韩敬美杨钰婷段沅杏田永峰秦云华陈永宽缪明明
Owner CHINA TOBACCO YUNNAN IND
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