A kind of pharmaceutical composition for treating children's permanent tooth periodontitis and its application

A technique for periapical periodontitis and a composition, applied in the field of traditional Chinese medicine, can solve the problems of poor curative effect, severe gastrointestinal irritation in children, and high cost of western medicine treatment.

Active Publication Date: 2018-05-11
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1. Some children are allergic to western medicines such as penicillin, spiramycin, and metronidazole
[0005] 2. Some children have poor curative effect when using targeted western medicines such as penicillin and spiramycin
[0006] 3. Western medicines are more irritating to the stomach of children, and often bring great side effects such as anorexia, which hinders clinical promotion
[0007] 4. The cost of western medicine treatment is too expensive
However, the traditional Chinese medicine is still unsatisfactory in the treatment of apical periodontitis, especially in children's permanent teeth, and needs further improvement.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] A pharmaceutical composition for treating periapical periodontitis of children's permanent teeth according to the present invention comprises the following raw materials of traditional Chinese medicine: 8 grams of Coptidis Rhizome, 12 grams of Radix Paeoniae Rubra, 15 grams of Licorice Root, 3 grams of Calculus Bezoar, 12 grams of Eucommia Eucommia, 12 grams of Zhimu, 10 grams of Jitian, 9 grams of Liao Diaozhu, 15 grams of Tianqi, 15 grams of Zihuadiding, 8 grams of Qingdai, 5 grams of honeysuckle, 3 grams of Cimicifuga, 14 grams of dandelion, 9 grams of Smilax, 6 grams of Asparagus, Yuanshen 8 grams, Sichuan Achyranthes bidentata 1 gram, Tribulus terrestris 10 grams, Ligustrum lucidum 16 grams.

Embodiment 2

[0053] A pharmaceutical composition for treating periapical periodontitis of children's permanent teeth according to the present invention comprises the following raw materials of traditional Chinese medicine: 10 grams of Coptidis Rhizome, 16 grams of Radix Paeoniae Rubra, 10 grams of Licorice Root, 8 grams of Calculus Bezoar, 5 grams of Eucommia Eucommia, 17 grams of Anemarrhena, 12 grams of Jitian, 4 grams of Liao Diaozhu, 20 grams of Tianqi, 10 grams of Zihua Diding, 12 grams of Qingdai, 2 grams of honeysuckle, 7 grams of Cimicifuga, 11 grams of Dandelion, 15 grams of Smilax, 3 grams of Asparagus, Yuanshen 13 grams, Sichuan Achyranthes bidentata 3 grams, Tribulus terrestris 5 grams, Ligustrum lucidum 13 grams.

Embodiment 3

[0055] A pharmaceutical composition for the treatment of periapical periodontitis of children's permanent teeth of the present invention, the following Chinese medicine raw materials are taken: Coptidis 5 grams, Radix Paeoniae Rubra 14 grams, Radix Glycyrrhizae 13 grams, Calculus Calculus 4 grams, Eucommia 6 grams, Anemarrhena 13 grams, Baba 7 grams of Jitian, 5 grams of Liao Diaozhu, 18 grams of Tianqi, 11 grams of Viola, 9 grams of Qingdai, 4 grams of honeysuckle, 6 grams of Cimicifuga, 12 grams of dandelion, 13 grams of Smilax, 4 grams of Asparagus, Yuanshen 9 grams, Sichuan Achyranthes bidentata 2 grams, Tribulus terrestris 6 grams, Ligustrum lucidum 14 grams.

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PUM

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Abstract

A pharmaceutical composition for treating periapical periodontitis of permanent teeth in children. The raw materials of the pharmaceutical composition are composed of Coptidis Rhizome, Chishao, Anemarrhena, Calculus Calculus, Eucommia, Morinda officinalis, Tianqi, Viola, Indigo Daisy, Licorice, Composition of honeysuckle, Achyranthes bidentata, Cimicifuga, Smilax smilax, Ligustrum lucidum, asparagus, ginseng, Tribulus terrestris, dandelion, and bamboo. The medicinal composition has good absorption, fast curative effect and no toxic and side effects. Moreover, it adopts commonly used Chinese herbal medicines, has perfect compatibility, master-slave order, simple preparation, quick effect, low cost, effectively reduces the living burden of ordinary families, and has good application prospects.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating periapical periodontitis of children's permanent teeth and an application thereof. Background technique [0002] Periodontal periodontitis is a chronic infectious disease of periodontal support tissue caused by anaerobic bacteria. Inhibiting and killing pathogenic bacteria plays an important role in the treatment and prevention of periodontitis. Studies have shown that Porphyrobacter gingivalis (Pg) is a well-documented pathogen of periodontitis, while Prevotella intermedia (Pi) is a moderately associated pathogen of apical periodontitis, with Actinobacillus actinomycetes (Aa) It is the main pathogenic bacteria of children's periodontitis, and the above-mentioned bacteria can cause great damage to children's teeth, especially permanent teeth. [0003] At present, antibiotics and western medicines are often used to treat child...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/90A61K36/8964A61P1/02A61K35/413
Inventor 陈宜辉刘家宁卢恕来董刚
Owner QINGDAO MUNICIPAL HOSPITAL
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