A kind of preparation method of graphene/hydroxyapatite composite material

Abstract

The invention provides a preparation method of a graphene / hydroxyapatite composite material. The preparation method of the graphene / hydroxyapatite composite material comprises the following steps of (1), preparing a mixed solution I, of which the concentrations in percentages by mass of graphene and calcium ions are 0.5 percent to 10 percent and 0.5 percent to 3 percent respectively; (2), adding a phosphate solution into the mixed solution I according to the mass ratio, which is (0.5 to 3) to 1, of calcium in the mixed solution I to phosphorus in the phosphate solution, and mixing an obtained mixture, so as to obtain a mixed solution II; (3), carrying out atomization and pyrolysis on the mixed solution II by adopting ultrasonic pyrolysis of which the ultrasonic power is 1,000w to 1,200w, the transducer frequency is 5MHz to 7MHz, the pyrolysis temperature is 550 DEG C to 650 DEG C and the pyrolysis reaction time is 10min, so as to obtain the graphene / hydroxyapatite composite material. According to the preparation method, graphene can be directly used as a raw material; a manufacturing procedure is simplified; meanwhile, a finished product has finer and further more uniform crystalline grains; furthermore, the better mechanical property and adsorbability and the favorable biocompatibility are provided.

Description

technical field [0001] The invention belongs to the production field of nano composite materials, in particular to a preparation method of graphene / hydroxyapatite composite materials. Background technique [0002] Hydroxyapatite, also known as hydroxyapatite, is a biologically adaptable biomedical material whose composition and structure are similar to the inorganic substances in bones, and belongs to a biological material that can be implanted into the human body Ceramics have good mechanical properties and excellent biological adaptability. Once placed in liquid, they can easily react with biological tissues to form chemical bonds. Therefore, they are very suitable for biological repair materials and have been used in dental and Biomaterials in Orthopedics. [0003] Graphene (Graphene), as an emerging nanoscale material, has excellent electrical, mechanical, optical and thermal properties, and also has the characteristics of large specific surface area and light weight, m...

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Problems solved by technology

[0006] In the preparation method provided by the above-mentioned patent, graphene oxide is used as the raw material. Although graphene oxide is rich in carboxyl groups, it is beneficial to the adsorption of calcium ions. However, graphene oxide needs to be obtained by oxidation of graphene, which exists widely in nature, through strong acid oxidation. , the price is high, and the mechanical properties, electrical conductivity and adsorption of graphene oxide are poor, and graphene oxide needs to be reduced to graphene in the follow-up, and the process is relatively cumbersome

In addition, since the above-mentioned patent uses a hydrothermal method to precipitate HA from an aqueous solution, the obtained HA crystals are relatively large, and the crystal particle size is generally 2 to 5 microns.

Because the particles are large, the pores between the particles are large. When the composite material is used in the human body, it is necessary to rely on the new bone tissue of the human body to fill these pores, and the healing and recovery time will be longer. In addition, if the gap between the particles If the pores are not filled, the hardness of the composite material will be greatly reduced

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