Traditional Chinese medicine preparation for treating chronic gastric ulcer

A technology for chronic gastric ulcers and traditional Chinese medicine preparations, which is applied in the directions of medical preparations, drug combinations, and pharmaceutical formulations containing active ingredients, and can solve the problems of large toxic side effects and insignificant therapeutic effects of western medicines.

Active Publication Date: 2015-10-28
启东市昌隆蔬果专业合作社
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its purpose is to solve the problem of treating chronic gastric ulcer, overcoming the problem of large toxic and side effects of western medicine and insignificant therapeutic effect, and achieving the goal of treating both symptoms and root causes

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A traditional Chinese medicine preparation for chronic gastric ulcer, prepared from the following raw materials in weight ratio:

[0030] Dendrobium candidum 50 parts, black medicine 45 parts, peach kernel 45 parts, bergamot 40 parts, coix seed 40 parts,

[0031] 35 parts of white lentils, 35 parts of Bupleurum, 35 parts of Magnolia officinalis, 30 parts of Panax notoginseng, 30 parts of myrrh,

[0032] Cyperus 30 parts, Licorice 28 parts, Dandelion 25 parts, Achyranthes bidentata 25 parts, Poria cocos 20 parts,

[0033] 20 parts of gallinaceous gold, 10 parts of Citrus aurantium, 10 parts of Ophiopogon japonicus, 10 parts of tangerine peel, 7 parts of Atractylodes macrocephala, and 7 parts of frankincense.

[0034] The preparation method is: according to the above weight ratio, the raw material medicine is taken for subsequent use:

[0035] (1) Take peach kernel, coix seed, magnolia officinalis, Panax notoginseng, myrrh, Cyperus cyperi, Ophiopogon japonicus, tangerin...

Embodiment 2

[0039] Example 2 Functional experiment

[0040] Acute Toxicity Study

[0041] Sixty healthy rats were given the traditional Chinese medicine preparation for chronic gastric ulcer prepared in Example 1 by oral gavage once, and the gavage dose was 150 times of the intended clinical dosage. After the administration, the mice showed a slight decrease in activity and returned to normal in about 1 hour. After the administration was observed continuously for 7 days, no animal died. Their general conditions, diet, water intake, urination and weight growth were normal, and no obvious acute symptoms appeared. Toxic reactions did not cause animal death. Mice did not show obvious acute toxicity, but rats showed loose stools and decreased activity, and the target organs of acute toxicity were liver and spleen. It is suggested that the drug has low acute toxicity and is safe for clinical use.

[0042] pharmacological research

[0043]Take 60 healthy rats, weighing 175±20g, half male and...

Embodiment 3

[0048] 1. Clinical data

[0049] 122 patients with chronic gastric ulcer with complete clinical data were randomly divided into treatment group and control group, divided into two groups on average, 61 people in each group, there was no significant difference in gender, age, disease course, etc. between the two groups (P>0.05) , are comparable.

[0050] 2. Diagnostic criteria

[0051] With reference to the "Guiding Principles for Clinical Research of Digestive System Drugs" promulgated by the Ministry of Health in 1993, stomach heat syndrome: burning pain in the epigastric cavity, thirsty mouth, cold drinks, and acid regurgitation. Swollen and painful gums, dry stool, yellow urine, red tongue with yellow coating. Stomach Cold Syndrome: cold pain in the epigastric cavity, severe pain, severe cold and mild mild, vomiting clear water, thick white fur. Epigastric pain due to blood stasis: epigastric pain, like acupuncture, fixed and persistent, refusal to press, dark purple ton...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine preparation for treating chronic gastric ulcer. The traditional Chinese medicine preparation for treating chronic gastric ulcer is prepared from the following raw materials including dendrobium officinale, combined spicebush roots, peach seeds, fingered citron, semen coicis, white hyacinth beans, Chinese thorowax roots, magnolia bark, pseudo-ginseng, myrrh, cyperus rotundus, liquorice, dandelions, roots of bidentate achyranthes, poria cocos, chicken's gizzardskin, fructus aurantii, ophiopogon japonicus, orange peel, bighead atractylodes rhizomes and boswellia carterii. The prepared traditional Chinese medicine preparation can solve the current problems and eliminate the root causes of the chronic gastric ulcer, has no side effects on a human body, is low in cost, can take effects fast and has wide application prospects.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine preparation for chronic gastric ulcer. Background technique [0002] Chronic gastric ulcer is a common gastric disease, which refers to tissue damage beyond the muscularis mucosa caused by the digestion of the gastrointestinal mucosa by the gastric digestive juice itself. It can occur in any part of the digestive tract, among which the stomach and duodenum are the most common, namely gastric ulcer and duodenal ulcer. The etiology, clinical symptoms and treatment methods are basically similar, and the definite diagnosis mainly depends on gastroscopy. Mainly manifested as [0003] (1) Abdominal pain, the abdominal pain of ulcers in the body of the stomach is often on the left side of the midline of the upper abdomen or the upper left abdomen; for ulcers located in the high position of the lesser curvature of the s...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P1/04A61K35/57
Inventor 刘梅霞林文鑫汤晓
Owner 启东市昌隆蔬果专业合作社
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