Iodophor disinfection paste and preparation method thereof

A uniform iodine technology, applied in ointment delivery, antiviral agents, pharmaceutical formulations, etc., can solve the problems of short duration of bactericidal action, poor water solubility, easy to be oxidized, etc., to shorten healing time, control infection, and promote granulation The effect of tissue growth

Inactive Publication Date: 2015-11-11
沈阳光彩生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Iodine-containing preparations are currently recognized worldwide as excellent skin and mucous membrane disinfectants. They can quickly kill bacterial propagules, bacterial spores, Mycobacterium tuberculosis, fungi, and viruses. When treating wounds, there are problems such as high irritation, poor water solubility, easy sublimation, coloring, easy oxidation, and short duration of bactericidal effect.

Method used

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  • Iodophor disinfection paste and preparation method thereof
  • Iodophor disinfection paste and preparation method thereof
  • Iodophor disinfection paste and preparation method thereof

Examples

Experimental program
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preparation example Construction

[0089] The preparation method of the embodiment of the present invention is:

[0090] ①. Take purified water into a stirring tank, heat it to 60°C, add potassium iodate and citric acid in sequence under uniform stirring, and stir at uniform speed until uniform.

[0091] ②. Then add polyoxy(40) stearate, polyethylene glycol, and fatty alcohol polyoxyethylene ether in sequence, keep the temperature and continue to stir at a constant speed, and stop stirring after all the materials have melted into a uniform ointment base. Ointment base, keep the base temperature not lower than 60℃.

[0092] ③. Add polyvinylpyrrolidone iodine to the tank under stirring. After stirring, it will become a uniform viscous liquid. Continue stirring until it is allowed to mature at room temperature.

[0093] ④. Stir or cool down naturally to 35℃ or room temperature and stop curing.

[0094] ⑤. Dissolve glycerin, borneol, and mint in ethanol and add them to the tank under agitation and stir for 30 minutes until ...

Embodiment 1

[0097] The weight ratio of the raw materials of iodophor disinfectant cream is:

[0098]

[0099]

Embodiment 2

[0101] The weight ratio of the raw materials of iodophor disinfectant cream is:

[0102]

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Abstract

The invention aims to provide an iodophor disinfection paste being prepared from potassium iodate, citric acid, fatty alcohol, borneol, mint, ethanol, glycerol, polyethylene glycol, polyalkyloxygen (40) stearate, povidone iodine and purified water. The iodophor disinfection paste is suitable for disinfecting ruptured skin wounds such as burning, scale, bedsores and the like or polluted and infected wounds, and skin trauma and sport trauma and the like wounds. The iodophor disinfection paste can quickly kill purulent bacteria causing wound infection and bacteria and microorganism generated due to festers, thereby preventing and controlling infection. The disinfection paste has excellent formula so that the disinfection paste can improve discomfortableness on wound skin, has the effects of alleviating pain, preventing decay, regenerating tissue and moisturizing skin, and being free of scab. The iodophor disinfection paste can control infection, can promote growth of granulation tissues, can reduce healing time of the wound and can improve healing rate of the wound.

Description

Technical field [0001] The invention belongs to the technical field of pharmacy, and in particular provides an iodophor disinfectant ointment and a preparation method thereof. Background technique [0002] Iodine-containing preparations are currently recognized worldwide as an excellent skin and mucous membrane disinfectant. It has a rapid killing effect on bacterial propagules, bacterial spores, Mycobacterium tuberculosis, fungi and viruses, but liquid iodine is clinically effective. In wound treatment, there are problems such as high irritation, poor water solubility, easy sublimation, coloring, easy oxidation, and short duration of sterilization. Summary of the invention [0003] The purpose of the present invention is to provide an iodophor disinfectant paste with good disinfection effect, good safety and good stability and a preparation method thereof. [0004] The iodophor disinfectant paste of the present invention is characterized in that the weight ratio of the raw materia...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/534A61K47/48A61K9/06A61K47/02A61P17/02A61P31/04A61P31/10A61P31/12A61K31/045A61K33/18
Inventor 张晓薇
Owner 沈阳光彩生物科技有限公司
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