Sympathetic nerve mapping and ablation device and system

Abstract

The invention provides a sympathetic nerve mapping and ablation device and system. The device includes a guiding catheter, a mapping ablation tube and a handle part. The guiding catheter is a hollow tube with openings at both ends, which is sheathed outside the mapping ablation tube; It has a spiral structure, and a plurality of electrodes that can map and ablate the sympathetic nerves are arranged on the front surface of the mapping ablation tube, and each electrode has a mapping wire that is connected to the detector and the energy generator and The ablation guide wire; the handle part is connected with the guide catheter, and it has a component that can control the mapping ablation tube to protrude from the opening of the head end of the guide catheter or withdraw from the guide catheter. The device of the present invention can accurately map and ablate sympathetic nerve innervation points from the arterial adventitia during surgery, realize targeted detection and ablation of sympathetic nerves related to the disease, and avoid vascular damage and treatment resulting complications.

Description

technical field [0001] The invention relates to a medical device, in particular to a sympathetic nerve mapping and ablation device and system. Background technique [0002] Hypertension is a global public disease with high incidence and great harm. It is the main risk factor for stroke, coronary heart disease, heart failure, vascular disease and renal failure, and it is also increasingly causing public health problems. concerns. In particular, resistant hypertension is a malignant disease with a high fatality rate without effective drug treatment, and its patients need to take a variety of antihypertensive drugs with different mechanisms of action to control systolic and diastolic blood pressure. To a certain extent, it increases the economic burden of patients, and also increases the adverse reactions of drugs to a certain extent. Therefore, a new treatment method is needed for the treatment of hypertension, especially resistant hypertension. [0003] Medical research has...

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Problems solved by technology

[0005] The above-mentioned interventional treatment method in the renal blood vessels avoids the trauma of open surgery, but the current clinical treatment results still cannot meet the needs, and there are two main shortcomings: 1. The existing device does not mark the sympathetic nervous system around the renal artery. Therefore, it is impossible to confirm which / which site ablation effect is better, or more symptomatic, so it uses multi-point pull-net ablation, usually multi-point ablation (6-8 points) in the blood vessel, in order to hope It can cover effective sites, but it will cause more punctate damage to the intima of the renal artery; 2. The ablation electrode of the existing device performs ablation in the vessel cavity, and the radiofrequency energy must pass through the vessel wall to reach the adventitia to ablate the vessel The sympathetic nerve endings on the wall and the adventitia of the blood vessels, so greater energy must be used. However, large or excessive radio frequency energy will cause damage to blood vessels, especially the damage to the intima of blood vessels, and postoperative complications are unavoidable. The treatment effect is greatly affected

Based on the above characteristics and problems, there have been some reports of treatment-related complications and contraindications since this treatment method was launched, such as the recurrence of hypertension caused by scarred renal artery stenosis after multi-point ablation of the renal artery intima, Renal artery perforation and renal artery dissection aneurysm caused by excessive energy of the ablation catheter at a single point. In addition, this method cannot be applied to patients who are allergic to contrast agents, and patients with arterial embolism in the lower extremities and obvious atherosclerotic plaques in the abdominal aorta patients with congenital malformations of the renal arteries

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