Nystatin aqueous solution and preparation method thereof
A technology of nystatin and aqueous solution, applied in pharmaceutical formulations, medical preparations containing active ingredients, digestive system, etc., can solve the problems of inability to remove molds and toxins, low absorption rate and utilization rate, and inability to achieve therapeutic dosage, etc. To achieve the effect of improving poultry production performance, high absorption rate and utilization rate, and relieving immunosuppression
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Embodiment 1
[0023] An aqueous solution of nystatin, in parts by weight, comprising the following raw materials: 40 parts of nystatin, 40 parts of propolis, 30 parts of glucose oxidase, 100 parts of cumene, 200 parts of methyl isobutyl ketone, volume fraction 100 parts of 95% ethanol.
[0024] A preparation method for an aqueous solution of nystatin, comprising the following steps:
[0025] 1) Pulverize 40 parts by weight of nystatin and 30 parts by weight of glucose oxidase, the particle size of which is 325 mesh, and store it for later use;
[0026] 2) Mix 100 parts by weight of cumene and 200 parts by weight of methyl isobutyl ketone, put them into a liquid mixing tank, and incubate at a temperature of 60°C for 30 minutes;
[0027] 3) Add the pulverized nystatin and glucose oxidase in step 1) to the mixture of cumene and methyl isobutyl ketone obtained in step 2), stir thoroughly for 30 minutes at a stirring speed of 1100 rpm, then cool to room temperature, and Place for 2h, filter to...
Embodiment 2
[0032] An aqueous solution of nystatin, in parts by weight, comprising the following raw materials: 60 parts of nystatin, 60 parts of propolis, 40 parts of glucose oxidase, 200 parts of cumene, 400 parts of methyl isobutyl ketone, volume fraction 200 parts of 95% ethanol.
[0033] A preparation method for an aqueous solution of nystatin, comprising the following steps:
[0034] 1) Pulverize 60 parts by weight of nystatin and 40 parts by weight of glucose oxidase, the particle size of which is 400 mesh, and put it aside for later use;
[0035] 2) Mix 200 parts by weight of cumene and 400 parts by weight of methyl isobutyl ketone, put them into a liquid mixing tank, and incubate at 80°C for 20 minutes;
[0036] 3) Add the pulverized nystatin and glucose oxidase in step 1) to the mixture of cumene and methyl isobutyl ketone obtained in step 2), stir thoroughly for 40 minutes at a stirring speed of 1200 rpm, then cool to room temperature, Stand still for 4h, filter to obtain the...
Embodiment 3
[0041] An aqueous solution of nystatin, in parts by weight, comprising the following raw materials: 50 parts of nystatin, 50 parts of propolis, 35 parts of glucose oxidase, 150 parts of cumene, 300 parts of methyl isobutyl ketone, volume fraction 150 parts of 95% ethanol.
[0042] A preparation method for an aqueous solution of nystatin, comprising the following steps:
[0043] 1) Grinding 50 parts by weight of nystatin and 35 parts by weight of glucose oxidase, the particle size of which is 500 mesh, and put it aside for later use;
[0044] 2) Mix 150 parts by weight of cumene and 300 parts by weight of methyl isobutyl ketone, put them into a liquid mixing tank, and incubate at a temperature of 70°C for 25 minutes;
[0045] 3) Add the pulverized nystatin and glucose oxidase in step 1) to the mixture of cumene and methyl isobutyl ketone obtained in step 2), stir thoroughly for 35 minutes at a stirring speed of 1300 rpm, then cool to room temperature, Stand still for 3h, filt...
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