Partially degradable blood vessel stent and preparation method thereof

A vascular stent and mass percentage technology, which is applied in the field of partially degradable vascular stents and their preparation, can solve the problems of weak radial support force of magnesium alloy stents and poor light transmittance of stents, and achieve the effect of avoiding easy breakage.

Inactive Publication Date: 2016-03-16
汤敬东 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, magnesium alloy vascular stents also have certain disadvantages
The radial support force of the magnesium alloy stent is weak, and the light transmission of the stent itself is poor; the degradation rate of the magnesium alloy is relatively fast, and the time with good support force is shorter than the clinical expectation of about four months, which cannot meet the clinical needs

Method used

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  • Partially degradable blood vessel stent and preparation method thereof
  • Partially degradable blood vessel stent and preparation method thereof
  • Partially degradable blood vessel stent and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Such as figure 1 , figure 2 As shown, a partially degradable vascular stent is composed of single rings, and the single rings are connected to each other through connection points. The material of the single rings is a non-degradable metal material, and the connection points are made of degradable The magnesium alloy material, the composition and ratio of the magnesium alloy material are shown in Table 1.

[0062] Table 1: each component of the present invention and proportioning thereof

[0063]

[0064]

[0065]

Embodiment 2

[0067] A method for preparing a partially degradable vascular stent, the method comprising the following steps:

[0068] 1) Carry out stress relief annealing treatment with the magnesium alloy extruded rod of the proportioning in Table 1 as mentioned above;

[0069] 2) Machining the annealed bar into a tube blank and extruding;

[0070] 3) performing stress relief annealing on the extruded capillary;

[0071] 4) Laser cutting the annealed capillary into a stent blank;

[0072] 5) In order to remove the cutting residue, the cut and formed bracket is pickled and ultrasonically cleaned in an ultrasonic cleaning machine; pickling refers to: 5-30min, the pickling liquid formula is phosphoric acid 80-100ml / L, ammonium bifluoride 40-60g / L, the solvent is deionized water. Ultrasonic cleaning means: the acid-washed stent is ultrasonically cleaned with deionized water and absolute ethanol for 5-10 minutes respectively.

[0073] 6) Electrochemical polishing, ultrasonic cleaning and ...

Embodiment 3

[0075] A method for preparing a partially degradable vascular stent, the method comprising the following steps:

[0076] Step 1. According to the shape and size requirements of the inner cavity of the aluminum alloy waveguide, a soluble core is prepared from a soluble material;

[0077] Step 2, install the soluble core on the core support of the four-axis motion platform, and control the movement of the soluble core according to the preset trajectory through the X-axis, Y-axis, Z-axis and R-axis of the motion platform;

[0078] Step 3. After removing the oxide skin of the aluminum alloy billet, place it in the crucible, and fill the inert gas in the spray environment to ensure that the oxygen content in the low-oxygen environment is lower than 1PPM;

[0079] Step 4: Start the system heating program, and gradually heat the crucible to 100-150°C above the liquidus line of the aluminum alloy through the induction heater;

[0080] Step 5, measure the temperature of the crucible 1...

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Abstract

The invention belongs to the technical field of medical apparatus and instruments, and particularly relates to a partially degradable blood vessel stent and a preparation method thereof. When the partially degradable blood vessel stent is just implanted into a patient body, a close-loop structure is achieved, and after a period of time, alloy materials of connection points are degraded, rings are separated, and an open-loop structure is achieved. According to blood vessels with larger degree of crook or blood vessels on the joints, by means of the partially degradable blood vessel stent, magnesium alloy connection points are used, the defect that the close-loop structure is prone to fracture can be overcome, the enough support force of the close-loop structure to blood vessel walls is reserved, and it can be guaranteed that the blood flow of the blood vessel is unblocked.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and in particular relates to a partially degradable vascular stent and a preparation method thereof. Background technique [0002] Vascular stent is a medical interventional device used for angioplasty. It provides internal support to maintain the patency of the lumen by resisting external pressure. Vascular embolism caused by a variety of causes that cannot be treated surgically, [0003] Clinical conditions such as organ limb ischemia. [0004] The current stents can be divided into closed-loop stents and open-loop stents according to different stent meshes. The design feature of the closed-loop stent is to repeat each single loop to make the consistency and uniform coverage on the vessel wall. However, due to the closed-loop stent, the softness of the stent and the radial strength of the side struts are sacrificed. Therefore, closed-loop stents have strong support but poor flexibil...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/90A61L31/02
Inventor 汤敬东张执南甘树杰马国瑞冯怡雯张磊万众张慈
Owner 汤敬东
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