Oseltamivir phosphate oral liquid and preparation method thereof

A technology of oseltamivir phosphate and Wei oral liquid, which is applied in the direction of pharmaceutical formulations, medical preparations with no active ingredients, medical preparations containing active ingredients, etc., which can solve the problem of inability to ensure the safety of drug administration and unsuitable capsule dosage forms. , difficult to accurately administer and other problems, to achieve the effect of convenient carrying and taking, easy storage, and stable quality
CN105534890AInactive Publication Date: 2016-05-04SHANGHAI TAOHONG CHEM TECH
3 Cites 1 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI TAOHONG CHEM TECH
Publication Date
2016-05-04
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
Patent Text Reader

Abstract

The invention discloses oseltamivir phosphate oral liquid and a preparation method thereof. The oseltamivir phosphate oral liquid is prepared from, by weight, 0.2-0.4 part of oseltamivir phosphate, 0.03-0.05 part of a cosolvent, 0.03-0.05 part of aspartame, 0.03-0.05 part of a stabilizing agent, 0.03-0.05 part of ethyl p-hydroxybenzoate and 75-95 parts of water. The prepared oseltamivir phosphate oral liquid has the advantages of being small in taking dosage, rapid to absorb, stable in quality, convenient to carry and take, easy to preserve, good in stability, high in clearity and the like and is particularly suitable for industrial production.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the field of pharmaceutical preparations, and relates to an oseltamivir phosphate preparation and a preparation method thereof, in particular to an oseltamivir phosphate oral liquid and a preparation method thereof. Background technique

[0002] Oseltamivir Phosphate, Chemical Name: (3R,4R,5S)-4-Acetamido-5-Amino-3(1-Ethylpropoxy)-1-Cyclohexene-1-Carboxylic Acid Ethyl Phosphate .

[0003] Oseltamivir phosphate is the prodrug of its active metabolite, and its active metabolite (oseltamivir carboxylate) is a selective influenza virus neuraminidase inhibitor. The activity of neuraminidase, a glycoproteinase on the surface of viruses, is critical for the release of newly formed virus particles from infected cells and the further dissemination of infectious virus in humans.

[0004] The active metabolite of oseltamivir phosphate inhibits the neuraminidase activity of influenza A and B viruses. The half-inhibitory concentration of...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More