The invention provides a dyphylline tablet and a preparation method thereof, which relate to the technical field of medicine, including dyphylline, loquat dew, Chuanbei, mulberry, mugwort leaves, berberine, microcrystalline cellulose, hydroxypropyl methyl Cellulose, lubricant, antioxidant, vitamin C, vitamin E; the preparation method is as follows: wash Chuanbei, mulberry, mugwort leaf, and coptis, dry in low-temperature vacuum, and pulverize with supersonic airflow; add dihydroxyprophylline and mix evenly, Add water; add microcrystalline cellulose, hydroxypropyl methylcellulose, antioxidants, vitamin C, and vitamin E and mix well; pour the material into a granulator to make tablet cores; take lubricant, dry it, and crush it to the nanometer level , sprayed on the tablet core to obtain diprophylline tablets. The dihydroxyprophylline tablet of the present invention has high bioavailability, stable disintegration and dissolution speed, high dissolution rate, stable quality, stable drug release speed, convenient carrying and taking, simple process, few types of auxiliary materials, short production process and low cost. Low.