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Medical bio-fiber styptic powder material and preparation method thereof

A bio-fiber and hemostatic powder technology is applied in the field of biomedical hemostatic materials, which can solve the problems of limited wide application and unsatisfactory hemostatic effect, and achieve the effects of facilitating structural stability, improving water absorption efficiency, and shortening hemostasis time.

Inactive Publication Date: 2016-05-25
GUANGXI XINYE BIOLOGICAL TECH +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the hemostatic effect of these current technologies is not ideal, which limits their wide application in clinical practice.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] A medical biological fiber hemostatic powder material is composed of the following raw materials in percentage by weight:

[0044] Microporous starch 50%

[0045] Puffball spore powder 50%.

[0046] The surface pore diameter of the microporous starch is 6-15 μm, and the porosity of the microporous starch is above 90%.

[0047] The puffball spore powder is the puffball spore powder obtained by peeling off the outer skin of the puffball, digging out the contents and sieving the spores, drying the spores at 110 degrees Celsius, and passing through a sieve with a mesh size of 100 or more after crushing.

[0048] The preparation method of described microporous starch comprises the following steps:

[0049] Step A, add water to 100g of starch to prepare starch milk with a mass percentage concentration of 21%, then add 4g of sodium chloride, stir evenly, and ultrasonically vibrate for 1 hour;

[0050]Step B, adding 1% sodium trimetaphosphate relative to the starch mass, adj...

Embodiment 2

[0063] A medical biological fiber hemostatic powder material is composed of the following raw materials in weight percentage:

[0064] Microporous starch 60%

[0065] Puffball spore powder 40%.

[0066] The surface pore diameter of the microporous starch is 6-15 μm, and the porosity of the microporous starch is above 90%.

[0067] The puffball spore powder is the puffball spore powder obtained by peeling off the outer skin of the puffball, digging out the contents and sieving the spores, drying the spores at 120 degrees Celsius, and passing through a sieve with a mesh size of 100 or more after crushing.

[0068] The preparation method of described microporous starch comprises the following steps:

[0069] Step A, add water to 100g of starch to prepare starch milk with a mass percentage concentration of 23%, then add 6g of sodium chloride, stir evenly, and ultrasonically vibrate for 3 hours;

[0070] Step B, adding 2% sodium trimetaphosphate relative to the starch mass, adju...

Embodiment 3

[0085] A medical biological fiber hemostatic powder material is composed of the following raw materials in weight percentage:

[0086] Microporous starch 70%

[0087] Puffball spore powder 30%.

[0088] The surface pore diameter of the microporous starch is 6-15 μm, and the porosity of the microporous starch is above 90%.

[0089] The puffball spore powder is the puffball spore powder obtained by peeling off the outer skin of the puffball, digging out the contents and sieving the spores, drying the spores at 130 degrees Celsius, and passing through a sieve with a mesh size of 100 or more after crushing.

[0090] The preparation method of described microporous starch comprises the following steps:

[0091] Step A, add water to 100g of starch to prepare starch milk with a mass percentage concentration of 22%, then add 5g of sodium chloride, stir evenly, and ultrasonically vibrate for 2 hours;

[0092] Step B, adding 2% sodium trimetaphosphate relative to the starch mass, adju...

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Abstract

The invention relates to a bio-medicine hemostatic material, in particular to a medical bio-fiber styptic powder material and a preparation method thereof. The medical bio-fiber styptic powder material is composed of micro-porous starch and puffball spore powder. The micro-porous starch has the effects of a molecular sieve and can rapidly absorb water in blood to form instant gel to mechanically block a blood vessel crevasse. A large number of micro-porous fibers are stored in the puffball spore powder, the water in the blood can be rapidly absorbed, the blood vessel crevasse and exudation of blood capillaries can be mechanically blocked, and the micro-porous starch and the puffball spore powder jointly form physical barriers, and can isolate wounds and achieve the effects of adhesion prevention and instant hemostasis. The medical bio-fiber styptic powder material is used for hemostasis of exudation of various wounds and fresh tissue wound surfaces, small vessel bleeding and bleeding regions, and prevents adhesion.

Description

technical field [0001] The invention relates to the technical field of biomedical hemostatic materials, in particular to a medical biological fiber hemostatic powder material and a preparation method thereof. Background technique [0002] Hemostasis is an important link in the operation of various departments in the hospital, and plays a considerable role in the success of the operation and the safety of the patient. The normal hemostasis mechanism mainly includes three aspects: the contraction of small blood vessels, the activation of platelets and the activation of the coagulation system. Among them, the contraction of small blood vessels is the earliest response to hemostasis after trauma. After the blood vessels are damaged, the vascular smooth muscle constricts the blood vessels and slows down the blood flow through axon reflex, which is beneficial to blood coagulation and hemostasis. Platelets have the physiological function of adhering to the surface of wounds and fo...

Claims

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Application Information

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IPC IPC(8): A61L24/08A61L24/00
CPCA61L24/0005A61L24/0015A61L24/0036A61L24/08A61L2300/30A61L2300/412A61L2300/414A61L2300/418
Inventor 梁奕福
Owner GUANGXI XINYE BIOLOGICAL TECH
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