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Traditional Chinese medicine preparation for sclerotin healing of osteoporotic fracture

A traditional Chinese medicine preparation and osteoporosis technology, applied in the direction of non-central analgesics, medical preparations containing active ingredients, antipyretics, etc., can solve the long clinical healing time and high fracture nonunion rate of osteoporotic fractures and delayed healing rate, inconsistencies in the principal stress direction, etc., to achieve the effect of promoting tissue blood circulation, prolonging swimming time, and regulating gastrointestinal motility

Inactive Publication Date: 2016-06-01
NANYANG INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Osteogenesis in cartilage is slow, bony callus remodeling is accelerated (bone resorption is greater than bone formation), collagen fibers in the callus are loose, disordered and inconsistent with the direction of the principal stress, resulting in reduced fracture healing quality
Therefore, the clinical healing time of osteoporotic fractures is longer, the rate of fracture nonunion and delayed union is higher, and the probability of fracture after healing is also higher.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0116] A traditional Chinese medicine preparation for bone healing of osteoporotic fractures of the present invention is prepared according to the following raw materials in parts by weight: 1 part of Codonopsis pilosula, 2 parts of Radix Astragali, 1 part of Eucommia ulmoides, 1 part of Dipsacus, 1 part of Ligustrum lucidum, and 1 part of mulberry , 1 part of dogwood, 2 parts of medlar, 2 parts of Rehmannia glutinosa, 1 part of raspberry, 2 parts of Schisandra chinensis, 1 part of chrysanthemum, 2 parts of dodder, 1 part of Cistanche, 1 part of Cynomorium, 1 part of Epimedium, 1 keel 3 servings of oysters, 1 serving of tortoise shell.

Embodiment 2

[0118] A traditional Chinese medicine preparation for bone healing of osteoporotic fractures of the present invention is prepared according to the following raw materials in parts by weight: Codonopsis 4 parts, Astragalus 5 parts, Eucommia 4 parts, Dipsacus 4 parts, Ligustrum lucidum 4 parts, mulberry 4 parts , 4 parts of dogwood, 6 parts of medlar, 6 parts of Rehmannia glutinosa, 4 parts of raspberry, 5 parts of schisandra, 4 parts of chrysanthemum, 5 parts of dodder, 4 parts of cistanche, 4 parts of Cynomorium, 4 parts of epimedium, and 4 parts of keel 8 servings of oysters, 4 servings of tortoise shell.

Embodiment 3

[0120] A traditional Chinese medicine preparation for bone healing of osteoporotic fractures of the present invention is prepared according to the following raw materials in parts by weight: 2 parts of Codonopsis pilosula, 3.5 parts of Astragalus membranaceus, 3 parts of Eucommia ulmoides, 3 parts of Dipsacus, 3 parts of Ligustrum lucidum, and 3 parts of mulberry , 3 parts of dogwood, 5 parts of medlar, 5 parts of Rehmannia glutinosa, 3 parts of raspberry, 3.5 parts of schisandra, 3 parts of chrysanthemum, 3.5 parts of dodder, 3 parts of cistanche, 3 parts of Cynomorium, 3 parts of epimedium, 3 parts of keel 6 servings of oysters, 3 servings of tortoise shell.

[0121] Implementation of the preparation scheme: get 4085g of Chinese herbal decoction pieces according to Example 3, pulverize them, and add honey to make pills, such as the size of phoenix seeds (9g / ball).

[0122] Clinical Observation Data

[0123] (1) Main functions and therapeutic scope of the medicine of the prese...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine preparation for sclerotin healing of an osteoporotic fracture. The traditional Chinese medicine preparation is prepared from, by weight, 1-4 parts of radix codonopsis, 2-5 parts of milkvetch roots, 1-4 parts of cortex eucommiae, 1-4 parts of radix dipsaci, 1-4 parts of glossy privet fruit, 1-4 parts of mulberries, 1-4 parts of fructus corni, 2-6 parts of barbary wolfberry fruit, 2-6 parts of prepared radix rehmanniae, 1-4 parts of raspberries, 2-5 parts of Chinese magnoliavine fruit, 1-4 parts of flatstem milkvetch seeds, 2-5 parts of semen cuscutae, 1-4 parts of herba cistanche, 1-4 parts of herba cynomorii, 1-4 parts of herba epimedii, 1-4 parts of bone fossils of big mammals, 3-8 parts of concha ostreae and 1-4 parts of tortoise plastrons. All the medicinal materials jointly achieve the effects of benefiting qi for activating blood circulation, tonifying the kidney and strengthening the bone, relieving swelling and pain, promoting tissue blood circulation, increasing the blood flow volume, improving bone tissue metabolism, increasing the bone mineral density and achieving sclerotin healing.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine preparation for bone healing of osteoporotic fractures. Background technique [0002] Osteoporosis is an orthopedic disease caused by a variety of reasons, which plagues the healthy life of many people and causes many serious consequences. Among them, osteoporotic fracture is the more serious one. The healing process of osteoporotic fractures is completely different from that of ordinary fractures. The general fracture healing process is divided into hematoma mechanism evolution period, original callus formation period and callus reconstruction and modeling period; while the osteoporotic fracture healing process is divided into Fibrous callus, cartilaginous callus and bony callus. [0003] The histological observation of osteoporotic fracture healing shows that in the fibrous callus stage, fibroblasts mainly synthe...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P19/08A61P19/10A61P29/00A61K35/02A61K35/586A61K35/618
CPCA61K35/02A61K9/2068A61K35/586A61K35/618A61K36/185A61K36/296A61K36/344A61K36/39A61K36/40A61K36/46A61K36/481A61K36/57A61K36/605A61K36/638A61K36/64A61K36/73A61K36/79A61K36/804A61K36/815A61K2300/00
Inventor 徐国昌张霄王延柯赵旭林刘先娟
Owner NANYANG INST OF TECH
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