A kind of method that improves caprolactone yield

Abstract

The present invention discloses a method for improving the yield of caprolactone, and anhydride substances such as acetic anhydride, propionic anhydride, butyric anhydride, valeric anhydride, hexanoic anhydride, succinic anhydride, glutaric anhydride, adipic anhydride, phthalic anhydride and the like are added in the last phase of the reaction for production of caprolactone from cyclohexanone and a peracid to improve the yield of caprolactone. The method is simple and easy to implement and suitable for industrial application, can greatly reduce the production cost of the caprolactone, and brings huge economic benefits.

Description

technical field [0001] The invention belongs to the technical field of organic synthesis, and in particular relates to a method for increasing the yield of caprolactone. Background technique [0002] ε-caprolactone (ε-CL) is an important intermediate in organic synthesis, for example, it can be used to synthesize polycaprolactone and polycaprolactone polyol, and it can also be copolymerized or blended with other esters for modification. Caprolactone and its modified polymers have been widely used in degradable plastics and biomedicine because of their good biocompatibility, non-toxicity, biodegradability and good drug penetration. Polycaprolactone polyol is one of the starting materials of high-grade polyurethane materials. Since caprolactone is a temperature-sensitive substance, it is easy to self-polymerize into 2-10 molecular oligomers at high temperature, while in ε-caprolactone In the process of ester production, the temperature in the rectification process is high, an...

AI Technical Summary

Problems solved by technology

Polycaprolactone polyol is one of the starting materials of high-grade polyurethane materials. Since caprolactone is a temperature-sensitive substance, it is easy to self-polymerize into 2-10 molecular oligomers at high temperature, while in ε-caprolactone In the process of ester production, the temperature in the rectification process is high, and ε-caprolactone produces a certain degree of self-polymerization, resulting in an increase in the amount of waste and an increase in production costs, and the high-boiling point waste produced is a sludge-like fluid at room temperature, and it is placed for a period of time After turning into a solid, it is difficult to deal with, and it is a difficult environmental protection problem

However, the current method of azeotropic distillation cannot solve the above problems well.