Silver-loaded antibacterial dressing and preparation method thereof

Abstract

The invention relates to a silver-loaded antibacterial dressing and a preparation method thereof. The preparation method comprises the steps of dissolving silver salt components such as silver nitrate and silver acetate and stabilizing agent components such as poly-amido compounds, poly-hydroxyl compounds and poly-carboxyl compounds into deionized water, and then mixing the constituents uniformly, so that a silver salt antibacterial solution is obtained; dipping or soaking an antibacterial dressing substrate into the silver salt antibacterial solution, and conducting drying, so that silver loading of the antibacterial dressing substrate is achieved. The silver loading method of the silver ion antibacterial dressing is simple, easy to implement and suitable for large-scale production; the obtained silver-loaded antibacterial dressing has the excellent antibacterial property, silver ions can be released stably, oxidizing discoloration does not occur easily, falling of silver at a wound and pigment deposition are not caused easily, and the silver-loaded antibacterial dressing and the preparation method thereof can be widely applied to silver loading processing of various silver ion antibacterial dressings.

Description

technical field [0001] The invention relates to a medical dressing, in particular to a silver-loaded antibacterial dressing and a preparation method thereof. Background technique [0002] Clinically, wounds are susceptible to infection and difficult to heal, which is caused by the rapid reproduction of pathogens such as Staphylococcus aureus, Candida albicans, and Escherichia coli in a warm and humid environment on the surface of the wound. In order to control wound bacterial reproduction and prevent wound infection, a large number of medical dressings are widely used for wound coverage and protection, and antibiotics or various antibacterial materials should be considered when using medical dressings to help control hemostasis, protect wounds, and reduce infection , absorb secretions, maintain body temperature and promote wound healing. [0003] Although antibiotics and organic antibacterial agents work quickly, there are many types of bacteria, and the antibacterial effec...

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Problems solved by technology

[0004] At present, there are two main silver-loading methods for silver-loaded antibacterial dressings at home and abroad. One is to add silver-based antibacterial agents during the forming process of antibacterial dressing base materials, such as in alginate fiber spinning solution and chitin fiber spinning solution. Add silver-loaded zirconium phosphate powder, silver-loaded silica powder, etc., and then spin to obtain silver-loaded alginate fiber or silver-loaded chitin fiber, or mix silver-based antibacterial fibers into nylon, polyester and other chemical fiber chip particles. silver-loaded masterbatches, and then spin to obtain chemical fibers such as silver-loaded nylon and silver-loaded polyester, but this method is only suitable for chemical fibers or recycled fibers, not suitable for silver-loaded antibacterial dressings based on natural fibers The other is to prepare the nano-silver solution first, and then use the post-finishing method to treat the antibacterial dressing base material, but this method is often affected by the stability, dispersibility, particle size, etc. of the nano-silver solution system, and some The antibacterial dressing obtained by nano-silver finishing also has the disadvantage that the silver particles are easy to fall off, which causes problems such as pigmentation on the wound surface

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