Hydrogel mask matrix and preparing method thereof

A technology for hydrogel mask and matrix, which is applied to pharmaceutical formulations, cosmetic preparations, cosmetic preparations, etc., can solve the problems of insufficient physical strength and low adhesion, and achieve suitable mechanical strength, good gloss, and peeling off. complete effect

Active Publication Date: 2016-07-06
SHAANXI UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are problems such as insufficient physical strength; because the hydrogel itself is smooth, the adhesion is low; some

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Add 50mL of sodium glycerophosphate (GP) aqueous solution with a mass fraction of 56% to 25mL of a 2% sodium alginate (SA) aqueous solution in an ice bath with stirring, and continue stirring for 30 minutes to make it evenly mixed, and then add a mass fraction of 75mL of 5% carboxymethylcellulose sodium (CMC-Na) aqueous solution and 3g of azone were stirred for 30 minutes to make them evenly mixed to obtain a mixed solution A, which was set aside. Add 300 mL of an 8% mass fraction of polyvinyl alcohol (PVA1750±50) aqueous solution to a 50 mL mass fraction of 2% chitosan (CS, with a deacetylation degree of 80 to 95%) solution under stirring conditions, and continue stirring 30min, make it mix evenly, get the mixture B, set aside. The solvent that described chitosan solution adopts is 1% (mL / mL) hydrochloric acid aqueous solution, and azone consumption accounts for 0.5% of the total mass of five kinds of solutions of SA, GP, CMC-Na, CS, PVA.

[0024] Under the condition ...

Embodiment 2

[0026] Add 50 mL of GP aqueous solution with a mass fraction of 56% to 30 mL of a 2% SA aqueous solution in an ice bath with stirring, and continue stirring for 30 minutes to make it evenly mixed, then add 50 mL of a 5% CMC-Na aqueous solution and 5 g Menthol, continue to stir 30min, make it to mix uniformly, get mixed solution A, for subsequent use. Add 200 mL of 8% mass fraction of PVA (PVA1750±50) aqueous solution to 50 mL of 2% mass fraction of CS (80-95% deacetylation) solution under ice bath and stirring condition, and continue to stir for 30 minutes to make it evenly mixed , to get the mixed solution B, set aside. The solvent that described chitosan solution adopts is 0.5% (mL / mL) acetic acid aqueous solution, and menthol consumption accounts for 1% of the gross mass of five kinds of solutions of SA, GP, CMC-Na, CS, PVA.

[0027] Under the condition of ice bath and stirring, add the mixed solution B to the mixed solution A dropwise, and continue to stir for 30 minutes ...

Embodiment 3

[0029] Add 50 mL of GP aqueous solution with a mass fraction of 56% to 25 mL of a 2% SA aqueous solution in an ice bath with stirring, and continue stirring for 30 minutes to make it evenly mixed, then add 25 mL of a 5% CMC-Na aqueous solution and 2 g Lecithin, continue to stir for 30min, make it mix evenly, get mixed solution A, set aside. Add 150 mL of 8% mass fraction of PVA (PVA1750±50) aqueous solution to 50 mL of 2% mass fraction of CS (80-95% deacetylation) solution under ice bath and stirring condition, and continue to stir for 30 minutes to make it evenly mixed , to get the mixed solution B, set aside. The solvent that described chitosan solution adopts is 1% (mL / mL) hydrochloric acid aqueous solution, and lecithin consumption accounts for 0.7% of the total mass of five kinds of solutions of SA, GP, CMC-Na, CS, PVA.

[0030] Under the condition of ice bath and stirring, add the mixed solution B to the mixed solution A dropwise, and continue to stir for 30 minutes aft...

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PUM

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Abstract

The invention provides a hydrogel mask matrix and a preparing method thereof. The hydrogel mask matrix is prepared from, by mass, 2% of sodium alginate water solution, 56% of a sodium glycerophosphate water solution, 5% of a sodium carboxymethylcellulose water solution, 8% of a polyvinyl alcohol water solution and 2% of a chitosan solution, the raw materials are mixed uniformly, poured into a mold, cured in a water bath and subjected to multigelation for 2-4 times. The matrix raw material components are biomacromolecules and other natural and harmless components good in biocompatibility and skin affinity, safe and harmless to the human body, and ensure that the mask matrix is free of sensitization; the prepared matrix material is uniform, good in glossiness and good in peeling integrity, has fine jade texture and suitable surface viscosity and mechanical strength, and meets the requirement for the film-forming property and stretchability.

Description

technical field [0001] The invention relates to a gel base for facial application, in particular to a hydrogel mask base and a preparation method thereof. Background technique [0002] As a facial application product, facial mask has a higher content of functional ingredients than daily skin care products, and can solve skin problems to a certain extent. Therefore, the application of facial mask is becoming more and more common. The mask uses the short time covered on the face to temporarily isolate the outside air and pollution, increase the temperature of the skin and expand pores, promote the secretion and metabolism of sweat glands, and increase the oxygen content of the skin. The moisture in the mask penetrates into the stratum corneum of the skin to make it soft and increase elasticity; the sticky ingredients or powdery adsorbent in the mask can adhere to the dirt, metabolic waste and excess oil on the skin surface and pores, and Get it out of the way. At present, th...

Claims

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Application Information

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IPC IPC(8): A61K8/81A61K8/73A61K8/04A61K8/02A61Q19/00
CPCA61K8/0212A61K8/042A61K8/731A61K8/733A61K8/8129A61K2800/592A61K2800/805A61Q19/00
Inventor 常相娜陈跃鹏龚频王兰陈雪峰杨文娟马彩霞刘婵婵
Owner SHAANXI UNIV OF SCI & TECH
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