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Acne treating drug capable of inhibiting propionibacterium acnes

A technology for Propionibacterium acnes and acne, which is applied in the field of acne treatment medicine for inhibiting Propionibacterium acnes and the field of preparation thereof, can solve the problems of inability to inhibit sebaceous gland secretion, difficult to treat acne, stubborn acne and the like, and achieve quick and effective results Repeated recurrence, inhibition of sebum secretion, simple mixing effect

Inactive Publication Date: 2016-08-03
孙桂芝
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Oral antibiotics - Tetracyclines (minocycline, doxycycline, etc.) are the first choice. However, although the above-mentioned treatment methods can eliminate inflammation in a short period of time, they cannot fundamentally solve the pathogenic factors of acne. Inhibit the secretion of sebaceous glands, the root cause of hair follicle blockage is not resolved, the symptoms are not cured, acne often recurs quickly, and there are phenomena one after another
In addition, bacteria are prone to develop resistance to chemical fungicides, and the relapsed acne will be more difficult to treat, forming intractable acne, and it will be complicated by scarring and pigmentation, which will have disastrous consequences for the skin

Method used

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  • Acne treating drug capable of inhibiting propionibacterium acnes
  • Acne treating drug capable of inhibiting propionibacterium acnes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Mr. Hong, 31 years old, had whiteheads and acne in his pores. The skin thickens and the tissue near the pores becomes inflamed, causing red and swollen acne, especially on the chin. Adapalene gel for topical application was ineffective, followed by oral administration of doxycycline. The effect was not good, and the acne recurred repeatedly after it subsided. Use this invention:

[0039] 60g each of raw almonds, ebony, and purple chrysanthemum, 40g each of aloe vera, angelica dahurica, coptis, dijincao, moutan cortex, and bletilla striata, 20g each of xanthophyll, borneol, mugwort leaves, notopterygium, Burnet, Sijiqing, hive, and Patrinia, Licorice 10g; Sulfur 10g, 2ml: 0.25g Chloramphenicol Injection 5 sticks, 75% alcohol 2000g.

[0040] Preparation method: mix raw almonds, ebony plums, Viola chinensis, aloe vera, Angelica dahurica, Coptis chinensis, Dijincao, Moutan cortex, Bletilla striata, xanthophyll seeds, borneol, mugwort leaves, notopterygium, Burnet, Sijiqin...

Embodiment 2

[0044] Ms. Lu, 24 years old, the skin around the acne was red and slightly raised, with pain. A large amount of sebum accumulates in the hair follicles, blocking the hair follicles, and there is thick pus after festering. Oral antibiotic minocycline, topical medicine tretinoin cream are all invalid, use the present invention:

[0045] Raw almonds, ebony plums, and Viola chinensis each 80g, aloe vera, Angelica dahurica, Coptis chinensis, Dijincao, Moutan cortex, and Bletilla striata each 60g, xanthate seeds, borneol, mugwort leaves, notopterygium, Burnet, Sijiqing, hives, and Patrinia 40g each, Licorice 20g; sulfur 30g, 2ml: 0.25g chloramphenicol injection 15 sticks, alcohol 3000g with a volume fraction of 75%.

[0046] Preparation method: mix raw almonds, ebony plums, Viola chinensis, aloe vera, Angelica dahurica, Coptis chinensis, Dijincao, Moutan cortex, Bletilla striata, xanthophyll seeds, borneol, mugwort leaves, notopterygium, Burnet, Sijiqing, hive, Patrinia, licorice; ...

Embodiment 3

[0050] Mr. Gu, 19 years old, had miliary to pea-sized nodules on the face, translucent reddish-brown or brown, soft to the touch, with necrosis in the center, little therapeutic effect of external drugs, repeated recurrences, using the present invention:

[0051] Raw almonds, ebony plums, Viola chinensis each 70g, Aloe vera, Angelica dahurica, Coptis chinensis, Dijincao, Moutan cortex, Bletilla striata each 50g, Xanthogonia seed, Borneolum, Artemisia argyi leaves, notopterygium, Burnet, Sijiqing, hive, Patrinia 30g each, Licorice 15g; sulfur 20g, 2ml: 0.25g chloramphenicol injection 10 sticks, alcohol 2500g with a volume fraction of 75%.

[0052] Preparation method: mix raw almonds, ebony plums, Viola chinensis, aloe vera, Angelica dahurica, Coptis chinensis, Dijincao, Moutan cortex, Bletilla striata, xanthophyll seeds, borneol, mugwort leaves, notopterygium, Burnet, Sijiqing, hive, Patrinia, licorice; After mixing together, add water and soak for 30 minutes to 1 hour, heat an...

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Abstract

The invention discloses an acne treating drug capable of inhibiting propionibacterium acnes. The drug comprises the following components by weight: 60 to 80 grams of raw almond, 60 to 80 grams of dark plum, 60 to 80 grams of Chinese violet, 40 to 60 grams of aloe, 40 to 60 grams of dahurian angelica root, 40 to 60 grams of coptis, 40 to 60 grams of humifuse euphorbia herb, 40 to 60 grams of tree peony bark, 40 to 60 grams of bletilla striata, 20 to 40 grams of airpotato yam rhizome, 20 to 40 grams of borneol, 20 to 40 grams of folium artemisiae argyi, 20 to 40 grams of notopterygium root, 20 to 40 grams of garden burnet, 20 to 40 grams of Chinese holly, 20 to 40 grams of honeycomb, 20 to 40 grams of patrinia herb, 10 to 20 grams of licorice, 10 to 30 grams of sulfur, 5 to 15 chloramphenicol injections, wherein each 2 mL of chloramphenicol injection comprises 0.25 gram of chloramphenicol; and 2000 to 3000 grams of alcohol with a volume percentage of 75%. The drug has the advantages of simple formula, user-friendliness, good bactericidal effect, rapid effect on treating acnes, and difficult relapse, and can inhibit sebum secretion.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to an acne treatment medicine for inhibiting Propionibacterium acnes and a preparation method thereof. Background technique [0002] Acne, also known as acne, is caused by multiple factors, such as blockage of hair follicles by abnormally adherent exfoliated cells, local inflammation caused by bacterial (Propionibacterium acnes) proliferation and colonization, and abnormal keratinization of hair follicles and sebum production. Western Medicine: Antibiotics such as erythromycin, clindamycin, and tetracycline have been administered topically or orally to treat acne. Another example is the common chemical fungicides, hormones, astringents, anti-inflammatory agents, etc. in the market, such as topical drugs-retinoic acid (retinoic acid cream, adapalene gel, tazarotene gel), Benzoyl peroxide, antibiotics (clindamycin, erythromycin, chloramphenicol, etc.), azelaic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P17/10A61P31/04A61K35/64A61K33/04A61K31/165A61K31/045
CPCA61K36/8945A61K36/896A61K36/898A61K9/0014A61K31/045A61K31/165A61K33/04A61K35/63A61K36/185A61K36/19A61K36/232A61K36/237A61K36/282A61K36/47A61K36/484A61K36/704A61K36/71A61K36/718A61K36/736A61K36/739A61K36/80A61K36/86A61K36/886A61K2236/333A61K2236/331A61K2236/51A61K2236/39A61K2300/00
Inventor 孙桂芝
Owner 孙桂芝
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