Synthetic method of polymer-wrapped nitrogen-doped fluorescent carbon nanodots

Abstract

The invention belongs to the field of materials chemistry, and relates to a synthetic method of polymer-wrapped nitrogen-doped fluorescent carbon nanodots. The invention uses an ordinary polar solvent NMP as a carbon source and a nitrogen source, and conducts a one-step solvent thermal reaction, removal of residual impurities such as NMP and drying to obtain a polymer-wrapped nitrogen-doped fluorescent carbon nanodots. The present invention provides a novel method for preparing a polymer-wrapped nitrogen-doped fluorescent carbon nanodots. The prepared nanodots have the advantages of uniform size, stable and tunable fluorescence emission, high water dispersibility and good biocompatibility, and can be widely applied to cancer fluorescent imaging and fluorescence sensors. The method is simple for operation, low in cost, and suitable for large-scale production.

Description

technical field [0001] The invention belongs to the field of material chemistry and relates to a method for synthesizing polymer-wrapped nitrogen-doped fluorescent carbon nano-dots. Background technique [0002] It has been reported that the development of fluorescent materials is crucial for disease diagnosis, especially the imaging and diagnosis of tumors. At present, a variety of fluorescent materials, such as organic dyes, fluorescent proteins, and fluorescent semiconductor nanocrystals, have been widely studied and applied in the field of fluorescence imaging. However, organic dyes and fluorescent proteins have small absorption coefficients, low photobleaching thresholds, relatively unstable fluorescence emission, and semiconductor nanocrystals are highly toxic. These shortcomings or defects severely limit their applications in the field of biomedicine. Studies have shown that zero-dimensional carbon nanodots, especially nitrogen-doped carbon nanodots, have good biocom...

AI Technical Summary

Problems solved by technology

However, these methods are usually complex, time-consuming, and uneconomical due to numerous synthetic steps, harsh synthetic conditions, or special reagents

Not only that, in order to achieve a wider application of carbon nanodots, it is necessary to further improve the properties of carbon nanodots, such as improving fluorescence efficiency, increasing water dispersibility and biocompatibility, so that surface modification of carbon nanodots with polymers is required etc. will make the synthesis process more complicated and difficult to mass-produce

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