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Cordyceps sinensis compound ginseng chitosan oligosaccharide capsule and preparation method thereof

A technology of Cordyceps sinensis and chitosan oligosaccharide, applied in the directions of capsule delivery, drug combination, pharmaceutical formulation, etc., can solve the problems of increased albuminuria and serum creatinine level, dependence on dialysis treatment, etc., and achieves inhibition of occurrence and development, convenient consumption, and alleviation of complications. Effect

Active Publication Date: 2019-12-03
NAVY MEDICINE RES INST OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Diabetic nephropathy is characterized by microalbuminuria in the early stage, and massive albuminuria and elevated serum creatinine levels gradually develop in the disease. If not diagnosed and treated in time, diabetic nephropathy develops to end-stage renal disease and can only rely on dialysis treatment or even kidney transplantation , resulting in a huge psychological and economic burden on patients

Method used

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  • Cordyceps sinensis compound ginseng chitosan oligosaccharide capsule and preparation method thereof
  • Cordyceps sinensis compound ginseng chitosan oligosaccharide capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] 1. Capsule formulation

[0034] It comprises the following components: 30g of chitosan oligosaccharide, 5g of Cordyceps sinensis, 2g of ginseng, and 5g of plant starch.

[0035] 2. Capsule preparation method

[0036] Include the following steps:

[0037] (1) Take chitosan oligosaccharide and plant starch powder of formula quantity and place in agitator, put Cordyceps sinensis and ginseng of formula quantity into agitator after pulverizing;

[0038] (2) Weigh 1 to 2 g of auxiliary materials and 1 to 2 g of ingredients in the formula and add them to the mixer;

[0039] (3) fully stir the mixture in the step (2) evenly;

[0040] (4) Capsule the mixed material.

Embodiment 2

[0042] 1. Capsule formulation

[0043] It comprises the following components: 60g of chitosan oligosaccharide, 10g of Cordyceps sinensis, 5g of ginseng, and 10g of plant starch.

[0044] 2. Capsule preparation method

[0045] Include the following steps:

[0046] (1) Take chitosan oligosaccharide and plant starch powder of formula quantity and place in agitator, put Cordyceps sinensis and ginseng of formula quantity into agitator after pulverizing;

[0047] (2) Take the auxiliary material and batching of formula quantity and add to agitator;

[0048] (3) fully stir the mixture in the step (2) evenly;

[0049] (4) Capsule the mixed material.

Embodiment 3

[0051] 1. Capsule formulation

[0052] It comprises the following components: 90g of chitosan oligosaccharide, 15g of Cordyceps sinensis, 10g of ginseng, and 15g of plant starch.

[0053] 2. Capsule preparation method

[0054] Include the following steps:

[0055] (1) Take chitosan oligosaccharide and plant starch powder of formula quantity and place in agitator, put Cordyceps sinensis and ginseng of formula quantity into agitator after pulverizing;

[0056] (2) Take the auxiliary material and batching of formula quantity and add to agitator;

[0057] (3) fully stir the mixture in the step (2) evenly;

[0058] (4) Capsule the mixed material.

[0059] 2. Endocrine conditioning test

[0060] 1. Patient enrollment

[0061]A total of 272 patients with diabetic nephropathy who were treated in Changhai Hospital of Second Military Medical University from October 2014 to October 2015 were selected and randomly divided into 8 groups. The 8 groups are as follows:

[0062] 1) Cont...

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Abstract

The invention belongs to the field of traditional Chinese medicines and in particular relates to a compound capsule with caterpillar fungus, ginseng and oligochitosan and a preparation method thereof. The compound capsule with caterpillar fungus, ginseng and oligochitosan particularly comprises the following components: 30-90g of oligochitosan, 5-15g of caterpillar fungus, 2-10g of radix ginseng and 5-15g of plant starch; the preparation method of the capsule comprises the following steps: crushing the materials, mixing uniformly and then split charging the materials into the capsule. The compound capsule with caterpillar fungus, ginseng and oligochitosan prepared by the method can be applied to traditional Chinese medicine healthcare products for preventing hyperglycemia, resisting tumor and enhancing immunity of the body, is capable of preserving health and conditioning body; a significant effect can be achieved by frequently taking the capsule.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a moxifloxacin hydrochloride sodium hyaluronate slow-release nanogel and a preparation method thereof. Background technique [0002] my country is a country with a large incidence of diabetes and tumors. Diabetic nephropathy is one of the most important microvascular complications of diabetic patients, the main cause of end-stage renal failure, and the main cause of death and disability from diabetes. Diabetic nephropathy is characterized by microalbuminuria in the early stage, and massive albuminuria and elevated serum creatinine levels gradually develop in the disease. If not diagnosed and treated in time, diabetic nephropathy develops to end-stage renal disease and can only rely on dialysis treatment or even kidney transplantation , thus bringing a huge psychological and economic burden to patients. Diabetic nephropathy is a chronic progressive disease....

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K36/258A61P3/10A61P35/00A61P37/04A23L29/30A23L33/125A23L31/00A61K31/722
CPCA23V2002/00A61K9/4866A61K31/722A61K36/068A61K36/258A61K2300/00A23V2200/30A23V2200/308A23V2200/328A23V2250/511
Inventor 张阵阵储智勇张淼栾洁谷爱梅
Owner NAVY MEDICINE RES INST OF PLA
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