Biological composition dressing for preventing and treating HPV

Abstract

The invention provides a biological composition dressing for preventing and treating HPV. The biological composition dressing comprises PHPV protein, carbomer, glycerol, green tea extract and Yujie pure MP components. The biological composition dressing can be prepared in dosage forms of dressing suppository, gel dressing, lotion, film agent and the like. The biological composition dressing has an obvious effect on treating genital tract high-risk HPV infection and lower-level cervical lesions caused by high-risk HPV infection, blocking genital tract HPV infection, improving vaginal micro-environment, relieving vaginal loosening and drying symptoms, reducing vaginal inflammatory reaction and lowering the vaginal PH value.

Description

technical field [0001] The invention belongs to the field of high-tech biotechnology, and in particular relates to a biological composition dressing for preventing and treating HPV infection and its clinical application. Background technique [0002] HPV is a species-specific epitheliophilic virus, which is a small DNA virus with a double-stranded closed circle, containing about 8000 base pairs. These include 8 early open reading frames (E1-E8), 2 late reading frames and 1 non-coding long control region. In the early open reading frame, the E6 and E7 genes are the most important for cell growth stimulation, and the E6 and E7 proteins encoded by E6 and E7 cause the immortalization of cervical epithelial cells. The late reading frame L1 and L2 genes encode the major and minor capsid proteins of HPV, respectively, and assemble into the capsid of HPV. "Dissecting" HPV reveals that it consists of a coat of protein capsid and a wrapped core. The "raw material" of the capsid is ...

AI Technical Summary

Problems solved by technology

[0004] Existing HPV treatments include (1) physical therapy: the purpose is to remove visible tumors and subclinical infections, methods include: laser, microwave, freezing, electrocautery, surgical resection (LEEP knife in gynecology, etc.), photodynamic therapy, etc.; (2) drug treatment: 0.5% podophyllin tincture, 5% imiquimod, 50% trichloroacetic acid, fluorouracil ointment; (3) immunotherapy is to reduce recurrence and speed up the removal of lesions, and the drugs include: Interferon, interleukin, thymosin, transfer factor, BCG, isotretinoin, autovaccine, etc.; (4) therapeutic vaccine: clinically proven HPV vaccine can almost 100% prevent infection of some HPV strains, but it cannot Prevents infection with all types of virus strains and is expensive

In terms of treatment, the immunomodulatory drugs used because there are no specific drugs are generally unable to effectively prevent HPV infection, have unclear curative effects, and are expensive, which greatly limits their clinical use, especially in low-income countries. developing countries

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