Biological composition dressing for preventing and treating HPV

A composition and biological technology, applied in the directions of drug combination, drug delivery, medical preparations with inactive ingredients, etc., can solve the problems of inability to effectively prevent HPV infection, inability to prevent virus strain infection, unclear curative effect, etc., and achieve improvement. Vaginal microenvironment, blocking genital tract HPV infection, and consolidating the effect of antivirus

Inactive Publication Date: 2016-12-07
易金阳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Existing HPV treatments include (1) physical therapy: the purpose is to remove visible tumors and subclinical infections, methods include: laser, microwave, freezing, electrocautery, surgical resection (LEEP knife in gynecology, etc.), photodynamic therapy, etc.; (2) drug treatment: 0.5% podophyllin tincture, 5% imiquimod, 50% trichloroacetic acid, fluorouracil ointment; (3) immunotherapy is to reduce recurrence and speed up the removal of lesions, and the drugs include: Interferon, interleukin, thymosin, transfer ...

Method used

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  • Biological composition dressing for preventing and treating HPV
  • Biological composition dressing for preventing and treating HPV
  • Biological composition dressing for preventing and treating HPV

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] A biological composition dressing for the prevention and treatment of HPV infection, calculated in parts by weight, contains 0.0005% of PHPV protein, 7% of carbomer, 3% of glycerin, 4% of green tea extract, and 0.15% of Yujie pure MP; to prepare 100 grams The composition is taken as an example, take 0.0005 grams of PHPV protein, 7 grams of carbomer, 3 grams of glycerin, 4 grams of green tea extract, and 0.15 grams of Yujie pure MP, add them to 60 grams of deionized water, and use a high-speed disperser Make it fully cross-linked and dissolved, then dilute to 100 grams with deionized water and stir evenly, and then make gel or other clinically required preparations according to conventional methods.

Embodiment 2

[0034] A biological composition dressing for the prevention and treatment of HPV infection, calculated by weight, contains 0.0001% of PHPV protein, 5% of carbomer, 2% of glycerin, 1.2% of green tea extract, and 0.05% of Yujie pure MP; to prepare one hundred gram of the composition as an example, take 0.0001 gram of PHPV protein, 5 grams of carbomer, 2 grams of glycerin, 1.2 grams of green tea extract, and 0.05 grams of Yujie pure MP, add them to 70 grams of deionized water, and use a high-speed disperser Make it fully cross-linked and dissolved, then dilute to 100 grams with deionized water and stir evenly, and then make gel or other clinically required preparations according to conventional methods.

Embodiment 3

[0036] A biological composition dressing for the prevention and treatment of HPV infection, calculated by weight, contains 0.0009% of PHPV protein, 9% of carbomer, 5% of glycerin, 6% of green tea extract, and 0.3% of Yujie pure MP; to prepare one hundred gram of the composition as an example, take 0.0009 grams of PHPV protein, 9 grams of carbomer, 5 grams of glycerin, 6 grams of green tea extract, and 0.3 grams of Yujie pure MP, add them to 80 grams of deionized water, and use a high-speed disperser Make it fully cross-linked and dissolved, then dilute to 100 grams with deionized water and stir evenly, and then make gel or other clinically required preparations according to conventional methods.

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Abstract

The invention provides a biological composition dressing for preventing and treating HPV. The biological composition dressing comprises PHPV protein, carbomer, glycerol, green tea extract and Yujie pure MP components. The biological composition dressing can be prepared in dosage forms of dressing suppository, gel dressing, lotion, film agent and the like. The biological composition dressing has an obvious effect on treating genital tract high-risk HPV infection and lower-level cervical lesions caused by high-risk HPV infection, blocking genital tract HPV infection, improving vaginal micro-environment, relieving vaginal loosening and drying symptoms, reducing vaginal inflammatory reaction and lowering the vaginal PH value.

Description

technical field [0001] The invention belongs to the field of high-tech biotechnology, and in particular relates to a biological composition dressing for preventing and treating HPV infection and its clinical application. Background technique [0002] HPV is a species-specific epitheliophilic virus, which is a small DNA virus with a double-stranded closed circle, containing about 8000 base pairs. These include 8 early open reading frames (E1-E8), 2 late reading frames and 1 non-coding long control region. In the early open reading frame, the E6 and E7 genes are the most important for cell growth stimulation, and the E6 and E7 proteins encoded by E6 and E7 cause the immortalization of cervical epithelial cells. The late reading frame L1 and L2 genes encode the major and minor capsid proteins of HPV, respectively, and assemble into the capsid of HPV. "Dissecting" HPV reveals that it consists of a coat of protein capsid and a wrapped core. The "raw material" of the capsid is ...

Claims

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Application Information

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IPC IPC(8): A61K38/18A61K38/08A61K9/06A61K47/32A61K47/46A61K47/10A61K47/08A61P31/20A61P15/02
CPCA61K38/1808A61K9/0034A61K9/06A61K38/08A61K47/08A61K47/10A61K47/32A61K47/46
Inventor 易金阳
Owner 易金阳
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