Lutein ester microcapsule preparation and as well as preparation method and use thereof

A technology of lutein ester and microcapsule, which is applied in the field of lutein ester microcapsule preparation and its preparation, and can solve problems such as poor stability of microcapsules

Active Publication Date: 2017-01-04
CHENGUANG BIOTECH GRP CO LTD
View PDF4 Cites 11 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Publication No. CN103735532A provides a lutein ester microcapsule and its preparation method. No oil-soluble a

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0024] Example 1

[0025] 1) Add 512g of gum arabic, 0.064g of polysorbate-80, and 12.8g of ascorbic acid into 896g of purified water, stir at 70°C for 60 minutes to completely dissolve, and prepare the water phase.

[0026] 2) Add 64 g of lutein ester (80% content) to 6.4 g of rosemary extract, stir at 60°C for 30 minutes until completely dissolved, and obtain an oil phase.

[0027] 3) Slowly add the oil phase to the high-speed shearing water phase at a shear rate of 8000r / min and an emulsification time of 90min; then add 512g of 25% mass fraction of inulin aqueous solution, emulsify for 20min, and then homogenize by high pressure twice The homogenizing pressure is 120MPa.

[0028] 4) The emulsion is granulated in one step by a spray-fluidized bed drying method to obtain lutein ester microcapsules with a particle size of 40-100 mesh, and the content is 7.0. The spray drying conditions are: the inlet air temperature is 50°C, and the fluidized bed blast temperature is 80°C.

Example Embodiment

[0029] Example 2

[0030] 1) Add 472g of gum arabic, 0.67g of sucrose fatty acid ester and 12.6g of sodium ascorbate into 1035g of purified water, stir at 75°C for 60min to completely dissolve, and prepare the water phase.

[0031] 2) Add 45g of lutein ester (80% content) to 9g of rosemary extract, stir at 75°C for 30min until it is completely dissolved to obtain the oil phase.

[0032] 3) Slowly add the oil phase to the high-speed shearing water phase at a shear speed of 9000r / min and an emulsification time of 60min; then add 450g of a 30% mass fraction of inulin aqueous solution, emulsify for 15min, and then homogenize by high pressure twice The homogenizing pressure is 80MPa.

[0033] 4) The emulsion is granulated by a spray-fluidized bed drying method in one step to obtain lutein ester microcapsules with a particle size of 40-100 mesh, with a content of 5.3%. The spray drying conditions are: the inlet air temperature is 40°C, and the fluidized bed blast temperature is 70°C.

Example Embodiment

[0034] Example 3

[0035] 1) Add 66 g of modified starch, 0.18 g of polyglycerin fatty acid ester and 2.1 g of tea polyphenols into 180 g of purified water, and stir at 60°C for 60 minutes to completely dissolve to obtain an aqueous phase.

[0036] 2) Add 6g of lutein ester (80% content) to 1.8g of rosemary extract, stir at 70°C for 30min to completely dissolve to obtain the oil phase.

[0037] 3) Slowly add the oil phase to the high-speed shearing water phase at a shear rate of 10000r / min and an emulsification time of 30min; then add 75g of 20% inulin aqueous solution, emulsify for 10min, and then homogenize by high pressure twice The homogenizing pressure is 30MPa.

[0038] 4) The emulsion is granulated in one step by a spray-fluidized bed drying method to obtain lutein ester microcapsules with a particle size of 40-100 mesh, and the content is 5.2%. The spray drying conditions are: inlet air temperature 30°C, fluidized bed blast temperature 60°C.

[0039] The stability evaluation r...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Particle sizeaaaaaaaaaa
Granularityaaaaaaaaaa
Login to view more

Abstract

The invention discloses a lutein ester microcapsule preparation and as well as a preparation method and a use thereof. The lutein ester microcapsule preparation is prepared from the following raw materials in parts by weight: 1 part of lutein ester, 8-11 parts of wall material, 0.001-0.03 parts of water-soluble emulsifier, 0.2-0.35 parts of water-soluble antioxidant, 0.1-0.3 parts of oil-soluble antioxidant, 2-3 parts of inulin and 20-40 parts of purified water. The preparation method comprises the following steps: adding the wall material, the water-soluble emulsifier and the water-soluble antioxidant into the purified water, mixing to dissolve so as to obtain a water phase, melting the lutein ester in the oil-soluble antioxidant to obtain an oil phase, adding the oil phase into the high-speed shearing water phase for emulsification, adding water solution of the inulin into the high-speed shearing water phase for uniform emulsification, carrying out high-pressure homogenization, and spraying and granulating the homogenized emulsification to obtain microcapsules with the particle size of 40-100 meshes. The invention also discloses the use of the lutein ester microcapsule preparation in the preparation of food, medicines and healthcare products with the functions of losing weight and/or protecting eyes. According to the lutein ester microcapsule preparation and as well as the preparation method and the use thereof disclosed by the invention, the obtained product has a high stability and has the functional effects of protecting eyes and losing weight.

Description

technical field [0001] The invention belongs to the technical field of new resource food, and in particular relates to a lutein ester microcapsule preparation and its preparation method and application. Background technique [0002] Lutein esters are carotenoid fatty acid esters in the form of lutein and fatty acids. It widely exists in plants such as marigold, cabbage and corn, especially the highest content in marigold. It can absorb blue light that is harmful to the retina, and has anti-oxidation effects, and plays an important role in the prevention and treatment of age-related macular degeneration and cataract diseases. [0003] Lutein crystals are difficult to emulsify due to their special property of being insoluble in oil and water. In order to improve stability and expand its application range, lutein ester microcapsules have been developed at home and abroad. Since lutein esters are wrapped in continuous capsules In the tiny capsule formed by the material, it avo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A23L33/12A23L33/125A23P10/30A23L29/00A23L29/10A61K31/733A61K9/50A61P3/04A61P27/02A61K31/23
CPCA23V2002/00A61K9/50A61K31/23A61K31/733A23V2200/216A23V2200/222A23V2200/02A23V2200/30A23V2200/332A23V2250/5062A23V2250/21A61K2300/00
Inventor 徐建中贾新超高伟安晓东段志鹏
Owner CHENGUANG BIOTECH GRP CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap