Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Extraction method of radix bardanae general flavone

An extraction method and technology of total flavonoids are applied in pharmaceutical formulations, medical preparations containing active ingredients, antidote and other directions, which can solve the problems of high cost of reagent consumables, low product yield, complicated process, etc. The effect of high yield and purity and broad application prospects

Inactive Publication Date: 2017-01-04
FUYANG HUAIBANG MACHINERY
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, there are few techniques for extracting flavonoids from burdock, and most of them have defects such as high cost of reagent consumables, complicated process, low product yield and poor purity.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A method for extracting total flavonoids from burdock root, comprising the steps of:

[0022] Step 1) Clean the fresh burdock root, heat it in steam at 100°C for 20 minutes, take it out, cool it naturally, cut it into thin slices with a thickness of 3 mm, then dry it in an oven, crush it, and pass it through a 100-mesh sieve to obtain burdock root powder dry powder;

[0023] Step 2) Spread the dry powder obtained in step 1) into a flat layer with a thickness of 5mm, and then irradiate it under ultraviolet light for 30 minutes, and the ultraviolet intensity is 3000mW / cm 2 ;

[0024] Step 3) Soak the dry powder in step 2) in 6wt% sucrose solution for 30 minutes, centrifuge to collect the precipitate, and dry the precipitate in a cool and ventilated place;

[0025] Step 4) The precipitate obtained in step 3) was reflux extracted three times with ethanol with a volume fraction of 75%, each time for 30 minutes, the ratio of solid to liquid was 1g:10ml, combined the extract...

Embodiment 2

[0031] A method for extracting total flavonoids from burdock root, comprising the steps of:

[0032] Step 1) Clean the fresh burdock root, then place it in steam at 100°C for 15 minutes, take it out, cool it naturally, cut it into thin slices with a thickness of 3mm, then dry it in an oven, crush it, and pass it through a 100-mesh sieve to obtain burdock root powder dry powder;

[0033] Step 2) Spread the dry powder obtained in step 1) into a flat layer with a thickness of 5mm, and then irradiate it under ultraviolet light for 20 minutes, and the ultraviolet intensity is 3000mW / cm 2 ;

[0034] Step 3) Soak the dry powder in step 2) in 6wt% sucrose solution for 30 minutes, centrifuge to collect the precipitate, and dry the precipitate in a cool and ventilated place;

[0035] Step 4) The precipitate obtained in step 3) was reflux extracted three times with ethanol with a volume fraction of 75%, each time for 30 minutes, the ratio of solid to liquid was 1g:10ml, combined the ex...

Embodiment 3

[0041] Take embodiment 1 technology as an example to detect the impact of each parameter and condition on extraction efficiency:

[0042] Groups: control group 1, control group 2, embodiment 1 group;

[0043] Control group 1: without sucrose soaking and ultraviolet irradiation, other same as embodiment 1;

[0044] Control group 2: treated with activated carbon instead of flocculant, other same as in Example 1.

[0045] The determination of total flavonoids in the sediment is shown in Table 1:

[0046] Table 1

[0047] group Content mg / g burdock root dry powder purity% Example 1 24.3 33.2 Control group 1 14.6 29.7 Control group 2 20.8 21.8

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Thicknessaaaaaaaaaa
Login to View More

Abstract

The invention belongs to the technical field of plant extraction, and discloses an extraction method of radix bardanae general flavone. The extraction method comprises the following steps of: step 1) drying and pulverizing; step 2) performing ultraviolet treatment; step 3) performing soaking treatment; step 4) performing ethanol extraction; step 5) performing flocculation; and step 6) performing extraction and drying. The extraction method is capable of extracting an effective substance general flavone compound from radix bardanae, greatly improving the yield and the purity, reducing the material cost and increasing the benefits of enterprises and has extensive application prospects.

Description

technical field [0001] The invention belongs to the technical field of plant extraction, and in particular relates to a method for extracting total flavonoids from burdock roots. Background technique [0002] Burdock root, alias Eshi root, rat sticky root, beef vegetable, Campanulaceae, Compositae, Arctium plant root system, traditional Chinese medicine name, spindle-shaped, dark brown skin, wrinkled, functions: dispelling wind-heat, detumescence Toxic treatment wind poison face swelling. Li Shizhen of the Ming Dynasty called it "cut the seedlings and wash them as vegetables, take the roots and cook them, and expose them to preserves, saying that they are beneficial to people." It is called "long-term service, making light of one's life and being resistant to old age". Song Su Song once described burdock in this way: "The leaves are as long as taro, and they are brown like grape cores, and the shell is as small and thorny as chestnut wood." When Japan occupied Taiwan, loc...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/28A61P3/10A61P3/06A61P39/06
CPCA61K36/28A61K2236/10A61K2236/15A61K2236/17A61K2236/333A61K2236/39A61K2236/51
Inventor 朱敏强
Owner FUYANG HUAIBANG MACHINERY
Features
  • Generate Ideas
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com