Rapid opto-acoustic/ultrasonic sector-scanning imaging device with large view field and high resolution and method for same

Abstract

The invention discloses a rapid opto-acoustic/ultrasonic sector-scanning imaging device with a large view field and high resolution and a method for the same. The device comprises an integral probe, a laser emission module, a delay module, an ultrasonic emission/reception module, a signal collection module, and a computer control and image rebuilding module. Through electric and mechanical connection of the modules, large-scale tomography of an opto-acoustic mode and an ultrasonic mode can be achieved. According to the invention, a hollow focus-type ultrasonic detector is adopted, so that opto-acoustic and ultrasonic coaxial performance is achieved, and system resolution and detection sensitivity are enhanced; and a micro galvanometer sector scanning mode is adopted, so that large-scope rapid opto-acoustic/ultrasonic sector-scanning imaging is achieved. The device and the method belong to the technical field of biomedical images and non-destructive detection.

Description

technical field [0001] The invention relates to the technical field of photoacoustic microscopic imaging, in particular to a photoacoustic / ultrasonic sector-scan imaging device with a fast large field of view and high resolution and a method thereof. Background technique [0002] Photoacoustic imaging technology refers to that the light-absorbing medium irradiated by short-pulse light (pulse width < microseconds) rapidly heats up and expands after absorbing light energy. Since the irradiation time is much shorter than the heat conduction time inside the irradiated medium, instantaneous thermal expansion results. Ultrasonic signals (called photoacoustic signals) are stimulated. The ultrasonic sensor is used to receive the photoacoustic signal stimulated by the medium, and the image is reconstructed through a certain calculation algorithm, which can invert the distribution of light absorption inside the tissue. Functional imaging technology that combines the high contrast ...

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Problems solved by technology

[0004] 1. Imaging within a small field of view; 2. The imaging speed is slow; 3. The imaging mode is relatively simple

[0005] The patent application with application number CN201410232481.9 discloses a real-time multimodal photoacoustic human eye imaging system and its imaging method. The invention adopts a photoacoustic confocal design, which improves the sensitivity on the basis of optical resolution, but The above-mentioned patents still have some deficiencies: 1. The optical path adopts a structure of multiple reflections, which makes the adjustment of the optical path more troublesome; 2. The ultrasonic signal is received by the ultrasonic detector in the form of two reflections, which easily causes the loss of the ultrasonic signal and makes it difficult to determine the ultrasonic signal. Optimal Fixing Position for Detectors

The patent application with application number CN201310035024.6 discloses an integrated photoacoustic microscopy imaging probe. This invention uses a two-dimensional scanning galvanometer to realize scanning in a two-dimensional plane, but the patent still has the following deficiencies: 1. Scanning The range is small, the invention adopts a structure in which the light deflected by the laser is passed through the two-dimensional galvanometer and then passes through the hollow focused ultrasonic detector, in which the size of the aperture at the center of the ultrasonic detector limits the scanning range

2. The scanning speed is relatively slow. Due to the short scanning stroke in the one-dimensional direction, the acceleration and deceleration process of the motor takes a long time, which makes the overall average speed slow

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