Solid preparation for coating agent, and film and coated solid preparation formed from same

Abstract

The purpose of the present invention is to provide a coating agent and a film that is formed from the coating agent that impart gas barrier properties to a solid preparation while still ensuring fast disintegrability. The purpose of the present invention is also to provide a coated solid preparation wherein gas barrier properties and fast disintegrability are maintained and wherein cracks do not occur in a film under humidified conditions. The present invention provides a coating agent for a solid preparation, the coating agent including lactose and an expansive clay and not including a water-soluble polymer, the weight of the expansive clay being 20%-50% of the solid component weight.

Description

technical field

[0001] The present invention relates to a coating agent for solid preparations, a coating film formed therefrom, and a coated solid preparation. Background technique

[0002] In recent years, orally disintegrating tablets that disintegrate rapidly in the oral cavity have been developed as dosage forms of pharmaceuticals that are convenient for patients with reduced swallowing function due to disease, aging, and decreased saliva secretion.

[0003] As a coating of an orally disintegrating tablet, the following has been reported: a coating agent (coating agent) containing a water-soluble polymer is used to apply a coating to an orally disintegrating tablet having a hardness above a certain level. method (Patent Document 1); a method of applying a coating using a coating agent composed of a polyvinyl alcohol derivative and a specific water-soluble substance (Patent Document 2); and a specific carbohydrate and a water-insoluble inorganic compound or Coating of w...

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