A kind of alginate-based hydrogel dressing and preparation method thereof

Abstract

The invention relates to an alginate-based hydrogel dressing and a preparation method thereof, and belongs to the technical field of medical supplies. Raw materials of the invention are a compound of sodium alginate or other alginates and a thickener, a moisturizer and other functional matters, are subjected to swelling dosing, pre-crosslinking, film coating, spray crosslinking, constant-temperature crosslinking plasticizing and film-covering shear forming, and are then prepared into a three-dimensional water-containing grid structure through covalent cross-linking and ion cross-linking. The medical hydrogel dressing is a topical gel dressing, has good moisturizing performance, toughness and adhesion, is mainly suitable for superficial skin damage, such as cut wound, lacerated wound, scratch, burns, suture wounds and the like, protects skin wound healing of a patient, has effects of easing pain, inhibiting bacteria, resisting inflammation, keeping the wound moist, promoting wound healing, and improving the wound repairing quality, is more suitable for treating bedsore wounds, ulcer wounds and other sites hard to be bound after a surgery, can also be used for non-wound sites, and plays a role of moisturizing.

Description

Technical field [0001] The invention relates to the technical field of medical supplies. An alginate hydrogel dressing can provide a good moist environment for wound healing, and has a certain liquid absorption performance, creating a good healing environment and a basis for a drug delivery system, which is more specific than traditional colloidal dressings Its mechanical properties and moisturizing properties, its liquid content is more than 60%, and the liquid absorption is more than 2 times its own mass. It is suitable for all important periods of wound healing. It can also be entered into the clinical operating room, starting from the earliest stage. Effective nursing, it can prevent wound infection and adhesion during use, will not cause secondary injury to the wound when changing dressing, reduce patient pain, reduce the burden of medical workers, reduce medical expenses, and have good air permeability during the nursing process. The appearance is transparent and easy. Obs...

AI Technical Summary

Problems solved by technology

At present, alginic acid hydrogel dressings are commonly used in light and ion cross-linking methods, but there are disadvantages such as poor transparency, poor mechanical properties, and poor water retention and moisture content.