Attapulgite/polyacrylic acid nanocomposite gel containing antimonous oxide and preparation method thereof

Abstract

The invention discloses attapulgite / polyacrylic acid nanocomposite gel containing antimonous oxide and a preparation method thereof. The attapulgite / polyacrylic acid nanocomposite gel is characterized in that the attapulgite / polyacrylic acid nanocomposite gel is prepared from the following raw materials in parts by weight: 2 to 3 parts of antimonous oxide, 5 to 10 parts of attapulgite, 1 to 2 parts of kaolin, 15 to 20 parts of hydrochloric acid solution, 30 to 40 parts of zinc sulfate solution, a right amount of absolute ethyl alcohol, 1 to 2 parts of ethylene propylene diene monomer, 2 to 5 parts of silane coupling agent KH-570, 2 to 5 parts of silane coupling agent KH-550, 2 to 3 parts of chitosan, 0.4 to 1 part of cerium nitrate, 5 to 10 parts of acrylic acid, a right amount of nitrogen and a right amount of distilled water. The chitosan which is added to the attapulgite / polyacrylic acid nanocomposite gel is rich in amino groups, so that the amino groups can be supplied to be grafted to the attapulgite so as to participate in crosslinking, the stability of a network structure is increased, and additionally, the chitosan has good adsorbability, so that the carrying capacity of carriers can be increased; the antimonous oxide is added, so that the flame retardant property is increased.

Description

technical field [0001] The invention relates to an attapulgite carrier and its preparation, in particular to an attapulgite / polyacrylic acid nanocomposite gel containing antimony trioxide and a preparation method thereof. Background technique [0002] Drug carrier release and targeting system can reduce drug degradation and loss, reduce side effects, and improve bioavailability, so more and more attention has been paid to its research. Due to its unique amphiphilic structure, polymer surfactants can self-assemble to form various forms of aggregates, such as micelles, microemulsions, gels, liquid crystals, vesicles, etc. These aggregates have the ability to entrap drug molecules and at the same time have good permeability to the membrane, which has become an important research field of drug carriers. Attapulgite is a hydrous-rich magnesium-aluminosilicate mineral with attapulgite as the main component and a special fibrous crystal structure. Due to its excellent adsorption,...

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Problems solved by technology

[0003] In his master's thesis "Gel Phenomenon and Application of Attapulgite / Polymer Nanocomposites Prepared by In-Situ Polymerization", Zhu Longxiang prepared nanocomposite hydrogels using attapulgite and acrylic acid, but they are used as drug carriers. There are also problems of poor loading capacity, antibacterial properties, and slow-release properties