Methods for preparing piperazine and catalyst by gas-solid-phase catalytic synthesis of ethylene glycol

Abstract

The invention provides methods for preparing piperazine and a catalyst by gas-solid-phase catalytic synthesis of ethylene glycol. The raw material (ethylene glycol) is mixed with certain quantities of ammonia and nitrogen to react via an amination catalyst to produce piperazine and derivatives of piperazine; and nickel, iron, copper, zinc, cobalt and the like serve as active components or additives in the amination process, mordenite serves as a carrier, and the mixed metal oxide amination catalyst is prepared by the impregnation method. The conversion rate of ethylene glycol can reach 42%, and the selectivity of piperazine reaches 75%.

Description

technical field [0001] The invention belongs to the technical field of ethylene glycol catalytic application, and in particular relates to a method for preparing piperazine through catalytic amination of ethylene glycol and a preparation method for a corresponding supported composite metal oxide catalyst. Background technique [0002] Piperazine is mainly used in the pharmaceutical industry to make insect repellent, anti-tuberculosis, antihypertensive, and antibacterial drugs. It can be used to make dyes and prevent fading of printed and dyed fabrics. It can also be used as rubber vulcanization accelerators, antioxidants, Stabilizers, surfactants, polyurethane production aids, etc., are widely used due to their low toxicity and high economic value. [0003] The homogeneous synthesis process has been gradually eliminated due to serious environmental pollution and equipment corrosion. At present, the research at home and abroad mainly focuses on heterogeneous catalytic synthes...

AI Technical Summary

Problems solved by technology

[0010] The problem of above-mentioned synthetic piperazine method is to use ethanolamine, ethylenediamine or hydroxyethylethylenediamine as reaction raw material, at first will set out to prepare the raw material of synthetic piperazine from ethylene or ethylene oxide or ethylene glycol, and its raw material price is relatively high. high, the overall process is complex, and the cost of synthesizing piperazine is relatively high; secondly, the raw materials often need to be diluted with a large amount of diluent, resulting in high preheating energy consumption and separation costs, and a decrease in product yield; in addition, the required reaction temperature or pressure is relatively high. High, the reaction conditions are relatively harsh