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Regenerated cellulose wound dressing and preparation method thereof

A technology for regenerated cellulose and wound dressings, applied in the fields of medical science, absorbent pads, bandages, etc., can solve the problem that the tissue repair ability of wound dressing needs to be further improved, and achieve excellent tissue repair ability, accelerated healing, and excellent performance.

Inactive Publication Date: 2017-07-07
WUHU YANGZHAN NEW MATERIAL TECH SERVICE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although various wound dressings are applied to different clinical wounds due to their different characteristics, so far there is no ideal dressing that can meet the requirements of various wound repair and healing, and the tissue repair ability of the wound dressings in the prior art remains to be seen. further improvement

Method used

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  • Regenerated cellulose wound dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A regenerated cellulose wound dressing comprises the following raw materials in parts by weight: 60 parts of cotton linters, 5 parts of chitosan solution, 5 parts of alginate solution and 5 parts of silk protein solution.

[0026] Described chitosan solution adopts following method to prepare: take by weighing 0.2g chitosan, be dissolved in 40ml deionized water, preparation mass volume ratio is the chitosan solution of 20%, add 0.32g sodium chloride crystal and 0.5 ml glacial acetic acid, adjust the pH to 5.0 and mix and stir to obtain a chitosan solution;

[0027] The alginate solution is prepared by the following method: weigh 0.2g of alginate, dissolve it in 40ml of deionized water, prepare an alginate solution with a mass volume ratio of 20%, add 0.32g of sodium chloride crystals, and stir Until fully dissolved alginate solution.

[0028] The silk protein solution is prepared by the following method: heat 2L of deionized water to boiling, add 4g of sodium carbonate...

Embodiment 2

[0033] A regenerated cellulose wound dressing comprises the following raw materials in parts by weight: 70 parts of cotton linters, 10 parts of chitosan solution, 10 parts of alginate solution, 10 parts of silk protein solution and 3 parts of Chinese medicine extract.

[0034] Described chitosan solution adopts following method to prepare: take by weighing 0.2g chitosan, be dissolved in 40ml deionized water, preparation mass volume ratio is the chitosan solution of 20%, add 0.32g sodium chloride crystal and 0.5 ml glacial acetic acid, adjust the pH to 5.0 and mix and stir to obtain a chitosan solution;

[0035] The alginate solution is prepared by the following method: weigh 0.2g of alginate, dissolve it in 40ml of deionized water, prepare an alginate solution with a mass volume ratio of 20%, add 0.32g of sodium chloride crystals, and stir Until fully dissolved alginate solution.

[0036] The silk protein solution is prepared by the following method: heat 2L of deionized wate...

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Abstract

The invention provides regenerated cellulose wound dressing and a preparation method thereof, and belongs to the field of composite biological materials. The wound dressing comprises, by weight, 60-70 parts of cotton linter, 5-10 parts of chitosan solution, 5-10 parts of alginate and 5-10 parts of silk protein solution. The prepared bombax ceiba composite regenerated cellulose wound dressing can be used for repairing and healing of various wound surfaces, and has a good tissue repair capacity.

Description

technical field [0001] The invention belongs to the field of composite biomaterials, in particular to a regenerated cellulose wound dressing and a preparation method thereof. Background technique [0002] When the skin is damaged, it is necessary to use skin repair materials as a temporary substitute for damaged skin to protect the wound, prevent wound infection and severe dehydration, provide a relatively moist environment for wound healing, and promote tissue regeneration and wound healing. Among many skin repair materials, autologous skin is the best repair material because it does not produce immune reaction and contains various tissue cells and active growth factors that promote repair and healing. Due to the limited source of autologous skin, it can only be used for small-scale skin damage, so when a large area of ​​skin is damaged, it is necessary to use other skin repair materials, such as medical wound dressings, skin scaffold materials, artificial skin, etc. as a t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/32A61L15/40A61L15/44A61L15/42
CPCA61L15/28A61L15/32A61L15/40A61L15/42A61L15/44A61L2300/232A61L2300/252A61L2300/30A61L2300/404A61L2300/412C08L1/02C08L5/08C08L5/04C08L89/00
Inventor 张春松吴长应
Owner WUHU YANGZHAN NEW MATERIAL TECH SERVICE CO LTD
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