Fiber-based three-dimensional porous composite material for bone repair, its preparation method and molded product

A three-dimensional porous and composite material technology, applied in medical science, prosthesis, tissue regeneration, etc., can solve the problems of not having a macroscopic three-dimensional structure, uneven distribution of internal fibers, and lack of mechanical support, etc., achieving low cost and easy molding , high security effect
CN107137773BActive Publication Date: 2020-04-07MEDPRIN REGENERATIVE MEDICAL TECH +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
MEDPRIN REGENERATIVE MEDICAL TECH
Publication Date
2020-04-07

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Abstract

The invention provides a fiber-based three-dimensional porous composite material for bone repair and a preparation method thereof and a molded product. The fiber-based three-dimensional porous composite material comprises micronano fiber powder and a binder, wherein the particle diameter of the micronano fiber powder is 10-500 micrometers, the diameter of fiber forming the micronano fiber powder is 0.1-100 micrometers, and the micronano fiber powder is evenly dispersed in the binder; the binder comprises biodegradable and self-curable inorganic components; the fiber-based three-dimensional porous composite material comprises, by mass, 5-50% of the micronano fiber powder, the porosity of the fiber-based three-dimensional porous composite material is 30-85%, and the compressive strength is 1-15 MPa. A constructed fiber-based three-dimensional connected porous scaffold is simple in preparation method and has a micronano fiber structure, so that the scaffold has a remarkable induced osteogenesis effect; the constructed fiber-based three-dimensional connected porous scaffold can better meet the filling demand of bone defect sites and can provide better mechanical properties.
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Description

technical field

[0001] The present invention relates to a fiber-based porous composite material for bone repair and its preparation method, and molded products prepared by using the fiber-based porous composite material, in particular to a three-dimensional porous scaffold and its preparation method, belonging to the technical field of tissue engineering repair . Background technique

[0002] At present, the number of fractures caused by work-related injuries and traffic accidents is gradually increasing, and the aging population also brings more diseases such as degenerative diseases of the spine and osteoporosis. Bone tumors, osteomyelitis, and hereditary bone diseases are also more common in clinical practice. orthopedic diseases. The self-healing ability of bone tissue is limited, and the bone defect cavity formed by most bone tissue diseases is difficult to heal. Surgical bone grafting is usually required to fill the defect to provide mechanical support and improve the...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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