Unlock instant, AI-driven research and patent intelligence for your innovation.

Preparation method of sodium alginate composite bioglass repair material

A technology of sodium alginate and bioglass, which is applied in the direction of alginate artificial filament, conjugated synthetic polymer artificial filament, tissue regeneration, etc., can solve the problems of poor mechanical properties and poor drug adhesion, and achieve the improvement of mechanical properties. Performance, lively nature, favorable effect of adhesion

Inactive Publication Date: 2017-09-08
HEFEI CHUANGWO TECH CO LTD
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in view of the existence of its amorphous silicon skeleton, bioglass still presents an amorphous form, poor mechanical properties, and poor drug adhesion, and its application in biomedical materials remains to be further developed

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A preparation method of sodium alginate composite biological glass repair material includes the following steps:

[0021] Step 1: Add 100g of brown algae to 1000mL of deionized water, wash and cut into 1cm×1cm squares, add 10% by mass to 120mL of Na with a mass concentration of 1.5% 2 CO 3 Digest in aqueous solution for 3 hours, then neutralize to neutral pH, dilute the digestion solution with 10 times the volume of water, stir and centrifuge to obtain the supernatant, add 5mg cellulase to the supernatant for enzymatic hydrolysis for 1 hour. Neutralize to neutral with acid buffer, then add 125mL CaCl with a mass concentration of 10% 2 The aqueous solution is subjected to calcium precipitation, and then acidified with 3% HCl by mass for 30 minutes to form alginic acid clot. After filtering off the HCl, wash with water until the pH is neutral, and add 6 times the volume of the alginic acid clot with 15% NaCl with a mass concentration. Ion exchange decalcification, and then ad...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A preparation method of a sodium alginate composite bioglass repair material belongs to the field of biomedical materials. The preparation method of the sodium alginate composite bioglass repair material is prepared through preparation of sodium alginate solution, preparation of bioglass solution and electrostatic spinning, wherein sodium alginate can improve the material mechanical performance, and the bioglass can improve the material medical performance. The obtained sodium alginate composite bioglass repair material is high in mechanical performance, tissue repair performance and drug adhesiveness.

Description

Technical field [0001] The invention belongs to the field of biomedical materials, and particularly relates to a preparation method of a sodium alginate composite bioglass repair material. Background technique [0002] Since the discovery of bioglass, people have paid more attention to the influence of bioglass components on biological activity. The rise of nanotechnology has enabled people to realize that structure also has an important impact on biological activity, and pay more attention to the impact of size effects and microscopic fine structures on the structure and performance of materials. The nano-bioglass and mesoporous bioglass developed and designed from the nanometer size have attracted the attention of domestic and foreign scholars. Bioglass can activate cell genes, help enhance cell proliferation and differentiation, and has the effects of osteoinduction and bone conduction. However, in view of the existence of its amorphous silicon framework, bioglass still pres...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61L27/56A61L27/58A61L27/50A61L27/20A61L27/18A61L27/02A61L27/00D01D5/00D01F9/04D01F8/16D01F1/10
CPCA61L27/56A61L27/00A61L27/025A61L27/18A61L27/20A61L27/50A61L27/58A61L2430/02D01D5/0015D01F1/10D01F8/16D01F9/04C08L5/04C08L71/02
Inventor 王吉鹏
Owner HEFEI CHUANGWO TECH CO LTD