Bacterial cellulose-polylactic acid composite film and its preparation method, drug-carrying gauze based on composite film and its preparation method
A technology of bacterial cellulose and polylactic acid film, applied in biochemical equipment and methods, methods based on microorganisms, coatings, etc., can solve the problems of increasing patient pain, unfavorable post-injury healing, easy adhesion of wounds, etc., and achieve good tissue Compatibility, good product stability, and good skin compatibility
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[0050] Example 1
[0051] A medical gauze based on a bacterial cellulose-polylactic acid composite film and a preparation method thereof, including the following steps:
[0052] (1) Prepare polylactic acid film (Polylacticacid film, PLA film) by electrospinning method: prepare a mixed solvent of chloroform and ethanol (2:1, v / v) to dissolve PLA to obtain a PLA solution with a mass concentration of 30%; take Inject 4.5mL PLA solution into a glass syringe syringe; cut Φ5cm tin foil paper, clamp it on the receiving end to form a receiver and connect one end of the wire to the receiving end; turn on the electrospinning machine, adjust the receiving distance to 10cm, and the spinning temperature to 40℃; install Injector, connect the voltage wire, open the voltage control area to apply voltage to the receiving end and the tip of the syringe; adjust the advancing speed to 0.1mm / s, start spinning, and form a PLA film on the receiver; after the film is dry, use tweezers to gently remove the...
Example Embodiment
[0055] Example 2
[0056] A medical gauze based on a bacterial cellulose-polylactic acid composite film and a preparation method thereof, including the following steps:
[0057] (1) Prepare polylactic acid membrane (Polylacticacid membrane, PLA membrane) by electrospinning method: prepare a mixed solvent of chloroform and ethanol (3:1, v / v) to dissolve PLA to obtain a PLA solution with a mass concentration of 35%; take Inject 5.5mL PLA solution into the glass syringe syringe; cut Φ7cm tin foil paper, clamp it on the receiving end to form a receiver and connect one end of the wire to the receiving end; turn on the electrostatic spinning machine, adjust the receiving distance to 15cm, and the spinning temperature to 50℃; install Injector, connect the voltage wire, open the voltage control area to apply voltage to the receiving end and the tip of the syringe; adjust the advancing speed to 0.2mm / s, start spinning, and form a PLA film on the receiver; after the film is dry, use tweezers...
Example Embodiment
[0060] Example 3
[0061] A medical gauze based on a bacterial cellulose-polylactic acid composite film and a preparation method thereof, including the following steps:
[0062] (1) Prepare polylactic acid film (Polylacticacid film, PLA film) by electrospinning method: prepare a mixed solvent of chloroform and ethanol (4:1, v / v) to dissolve PLA to obtain a PLA solution with a mass concentration of 40%; take Inject 6.5mL PLA solution into a glass syringe syringe; cut Φ10cm tin foil paper, clamp it on the receiving end to form a receiver and connect one end of the wire to the receiving end; turn on the electrostatic spinning machine, adjust the receiving distance to 20cm and the spinning temperature to 60℃; install Injector, connect the voltage wire, open the voltage control area to apply voltage to the receiving end and the tip of the syringe; adjust the advancing speed to 0.3mm / s, start spinning, and form a PLA film on the receiver; after the film is dry, use tweezers to gently rem...
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