Preparation method of cod skin collagen peptide composite regeneration fiber restoration material

A technology of composite regeneration and repair materials, which is applied in the fields of medical science, nonwovens, textiles and papermaking, etc., can solve the problems of tissue repair ability and drug adhesion that need to be further improved, composite film uniformity and poor stability, etc., to achieve Excellent degradability, good adhesion, and improved tissue repair ability

Inactive Publication Date: 2017-09-22
HEFEI CHUANGWO TECH CO LTD
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  • Summary
  • Abstract
  • Description
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AI Technical Summary

Problems solved by technology

However, most of the existing technologies use regenerated cellulose and other materials to blend and freeze-dry to prepare composite films. The uniformity and stability of the composite films prepared by this method are poor, and the tissue repair ability and drug adhesion need to be further improved.

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0025] Step 1: Take cod skin collagen, configure it into a collagen aqueous solution with a mass concentration of 1%, adjust the pH value of the collagen aqueous solution to 8.0, add 1% by mass alkaline protease, and perform enzymatic hydrolysis in a water bath at 50°C After 60 minutes, boil water to inactivate the enzyme for 10 minutes, cool to room temperature and centrifuge at 8000r / min for 15 minutes, take the supernatant and concentrate it to half of the original volume by rotary evaporation to obtain the cod skin collagen peptide extract;

[0026] Step 2: Weigh 20g of bamboo fiber, put it into 400g of NaOH solution with a mass fraction of 17.5%, and place it in a constant temperature water bath with a temperature of 100°C, boil for 60min, and then repeatedly clean the bamboo fiber with deionized water After reaching neutrality, place it in an oven at 70°C for 6 hours, and after drying, crush it into a coarse powder and pass it through an 80-mesh sieve to obtain bamboo pow...

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PUM

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Abstract

The invention provides a preparation method of a cod skin collagen peptide composite regeneration fiber restoration material, and belongs to the technical field of a tissue restoration material. The method comprises the steps of preparing cod skin collagen peptide, preparing bamboo nanometer fiber solution, preparing regenerated cellulose spinning liquid, performing static spinning, and obtaining the restoration material. The prepared tissue restoration material has good antibacterial performance, mechanical performance, tissue restoration performance and medicine addition performance.

Description

technical field [0001] The invention belongs to the technical field of preparation of tissue repair materials, and in particular relates to a preparation method of a cod skin collagen peptide composite regenerated fiber repair material. Background technique [0002] As a natural biopolymer, cellulose has biodegradability, biocompatibility and unique physical, chemical and mechanical properties, and has become a research hotspot in the field of new biomedical materials. However, most of the existing technologies use regenerated cellulose and other materials to blend and freeze-dry to prepare composite films. The uniformity and stability of the composite films prepared by this method are poor, and the tissue repair ability and drug adhesion need to be further improved. . Contents of the invention [0003] In order to solve the problems in the prior art, the present invention provides a method for preparing a cod skin collagen peptide composite regenerated fiber repair mater...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/24A61L27/20A61L27/22A61L27/54A61L27/56A61L27/58D04H1/728D04H1/4382
CPCA61L27/24A61L27/20A61L27/227A61L27/54A61L27/56A61L27/58A61L2300/232A61L2300/252A61L2300/404A61L2300/412D04H1/4382D04H1/728C08L89/00C08L1/02
Inventor 王吉鹏
Owner HEFEI CHUANGWO TECH CO LTD
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