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Porous metallic bar

A technology of porous metal and multi-level pores, which is applied in the field of porous metal rods for medical implantation, can solve the problems of weak interface between the implant and adjacent bone tissue, unfavorable fusion of the implant and femur, and unfavorable bone tissue regeneration. , to overcome interface instability, avoid stress shielding, and promote rapid growth

Active Publication Date: 2017-11-17
CHONGQING RUNZE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the porous material used in the porous tantalum rod is a material with a single void, and the cavity wall of the hole is still a dense material. After the porous tantalum rod is implanted, when the force is applied, although the overall elastic modulus of the material is low, it acts as a cavity. Due to the large elastic modulus of the dense material of the wall, it is difficult for the cells on the cavity wall of the porous material to feel the stimulation of the force, and stress shielding occurs, which is not conducive to cell growth, and is not conducive to the fusion of the implant and the femur. The growth factors and other drugs carried by the cavity wall of the dense material are limited, which is not conducive to the realization of bone tissue regeneration; further research has found that porous tantalum prepared by chemical vapor deposition of a single void is used as a bone implant, and bone tissue grows into the implant. The depth is less than 3mm, which makes the interface between the implant and the adjacent bone tissue unstable and loose, which affects the treatment effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A porous metal rod made of porous metal material, the porous metal rod consists of two parts, one part is a round rod-shaped part 1, the other part connected to it is a threaded part 2, the outside of which has threads, and the end surface of the threaded part 2 is provided with Notch 3, the outer diameter of the thread is larger than the outer diameter of the round rod. The porous metal material is a multi-level porous metal material. The multi-level porous metal material is divided into two levels. The first-level cavity 4 is a large hole with a diameter of 150 μm. -450µm, in a three-dimensional space surrounding the wall 5 that constitutes the first-stage cavity 4 is composed of a second-stage porous metal material, and the hole diameter of the second-stage porous metal material 6 is 370nm-600nm, and each stage of the cavity is connected to each other It is connected and the cavities at all levels are also connected to each other. The material is stainless steel 316L....

Embodiment 2

[0038] This embodiment is similar to Embodiment 1, except that the material used for the porous metal rod is pure titanium. The cavity 6 has a pore diameter of 450nm-750nm, a porosity of 45%, an elastic modulus of 72GPa, and the overall elastic modulus of the porous metal is 2GPa.

Embodiment 3

[0040] A porous metal rod, which is a multi-level porous metal material made of tantalum metal, has a three-level pore structure. The pore diameter is 300nm-450nm, the pores of each level of porous metal materials are connected to each other and the pores of each level of porous materials are also connected to each other, and the pores of each level of porous metal materials in the multi-level porous metal material The cavities are evenly distributed in the material body, and its preparation method is similar to that of Example 1, except that in the preparation of the porous tantalum material, the mixed particles obtained by crushing, the ethyl cellulose with a particle size of 45µm-75µm are divided by volume After uniform mixing at a ratio of 1:3, it is evenly poured into the three-dimensional polyester foam with a rib diameter of 460µm-580µm and a pore diameter of 600µm-830µm, and then the polyester foam is put into a closed mold and pressed into a dense green body. Vacuum s...

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Abstract

A porous metallic bar is made of a porous metallic material. The porous metallic bar includes two portions; one portion is a circular bar-shaped portion, and the other portion connected to the circular bar-shaped portion is a thread portion; threads are arranged on an outer part of the thread portion; the outer diameter of the threads is greater than the inner diameter of the circular bar-shaped portion; the porous metallic material is a hierarchical pore metallic material; a hierarchical pore metallic material body includes all levels of pore cavities which are graded according to the material pore size, and all levels of cavity walls forming the pore cavities; cavity walls of upper level pore cavities formed by three-dimensional spaces are made of a lower level porous metallic material; pore cavities at each level communicate with each other and all levels of pore cavities communicate with each other; and the number of levels is at least two. The porous metallic bar allows tissues to overgrow in the inner part of an implant body, tight fusion between the implant body and a thighbone can be achieved, the interface is stable and firm, loosening can be avoided, pain of a patient can be avoided, and the time of artificial hip joint replacement is delayed.

Description

technical field [0001] The invention relates to the field of prostheses, in particular to a medically implanted porous metal rod for treating early necrosis of the femoral head. Background technique [0002] Femoral head necrosis is a chronic progressive disease. It is caused by various reasons, such as ischemia, necrosis, trabecular fracture, and femoral head collapse. The main clinical manifestations are hip joint pain and dysfunction, and the disability rate is high. . There are more than 20 million patients with osteonecrosis of the femoral head in the world, of which 5-7.5 million are in my country. [0003] There are many treatment methods for adult osteonecrosis of the femoral head, each with its own advantages and disadvantages. When the disease develops to the stage of joint damage, artificial hip replacement is required. However, artificial hip replacement has many disadvantages such as infection, loosening, dislocation, and wear. Especially for young patients, d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/28
CPCA61F2/28A61F2/2846A61F2002/2825A61F2002/2835A61F2002/30332A61F2002/30433A61F2310/00011A61F2310/00017A61F2310/00023A61F2310/00029A61F2310/00095A61F2310/00131
Inventor 叶雷
Owner CHONGQING RUNZE PHARM CO LTD
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