Doped black phosphorus quantum dot thermal treatment syringeability bone cement as well as preparation and application thereof
A technology of quantum dots and bone cement, which is applied in the fields of preparation and application of injectable bone cement for thermal treatment of quantum dots doped with black phosphorus, can solve problems such as inability to degrade, and achieves improved biocompatibility, simple raw materials, and adaptability. effect on mass production
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Example Embodiment
[0033] Example 1
[0034] Disperse alpha-tricalcium phosphate in absolute ethanol to prepare a 40g / L solution, mix at 400rpm for liquid phase grinding for 4h, then add 10000:1 PLGA / black phosphorus quantum dots to the solution, and then add 0.5% The gelatin is continuously ball-milled in a ball mill for 15 minutes, and the resulting solution is rotary evaporated to obtain a powder. Among them, alpha-tricalcium phosphate: PLGA / black phosphorous quantum dots=10000:1
[0035] Weigh out 0.1g phosphorylated chitosan, 0.15g gelatin, and 0.1g hydroxypropyl methylcellulose, and dissolve them in 19.65g sodium hydrogen phosphate solution to prepare 20% sodium hydrogen phosphate, 1% phosphorylated chitosan, Bone cement curing liquid of 1.5% gelatin and 1% hydroxypropyl methylcellulose.
[0036] The bone cement powder and the solidification liquid were mixed at a solid-liquid ratio of 2-2.5g / mL, and the initial setting time was determined to be 12 min by referring to the standard ASTM C191.
Example Embodiment
[0037] Example 2
[0038] Disperse alpha-tricalcium phosphate in absolute ethanol into a 40g / L solution, mix at 400rpm for liquid phase grinding for 4h, then add 5000:1 PLGA / black phosphorus quantum dots to the solution, and then add 0.5% The gelatin is continuously ball-milled in a ball mill for 15 minutes, and the resulting solution is rotary evaporated to obtain a powder. Among them, alpha-tricalcium phosphate: PLGA / black phosphorous quantum dots=5000:1
[0039] Weigh out 0.1g phosphorylated chitosan, 0.15g gelatin, and 0.1g hydroxypropyl methylcellulose, and dissolve them in 19.65g sodium hydrogen phosphate solution to prepare 20% sodium hydrogen phosphate, 1% phosphorylated chitosan, Bone cement curing liquid of 1.5% gelatin and 1% hydroxypropyl methylcellulose.
[0040] The bone cement powder and the solidification liquid were mixed at a solid-liquid ratio of 2-2.5g / mL, and the initial setting time was determined to be 13 min by referring to the standard ASTM C191.
Example Embodiment
[0041] Example 3
[0042] Disperse alpha-tricalcium phosphate in absolute ethanol to prepare a 40g / L solution, mix at 400rpm for liquid phase grinding for 4h, then add 2000:1 PLGA / black phosphorus quantum dots to the solution, and then add 0.5% The gelatin is continuously ball-milled in a ball mill for 15 minutes, and the resulting solution is rotary evaporated to obtain a powder. Among them, alpha-tricalcium phosphate: PLGA / black phosphorous quantum dots=2000:1
[0043] Weigh out 0.1g phosphorylated chitosan, 0.15g gelatin, and 0.1g hydroxypropyl methylcellulose, and dissolve them in 19.65g sodium hydrogen phosphate solution to prepare 20% sodium hydrogen phosphate, 1% phosphorylated chitosan, Bone cement curing liquid of 1.5% gelatin and 1% hydroxypropyl methylcellulose.
[0044] The bone cement powder and the solidification liquid were mixed at a solid-liquid ratio of 2-2.5g / mL, and the initial setting time was 15 min by referring to the standard ASTM C191.
PUM
Property | Measurement | Unit |
---|---|---|
Particle size | aaaaa | aaaaa |
Particle size | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap