Application of black phosphorus nanosheet
A technology of nanosheets and black phosphorus, which is applied in nanotechnology, nanomedicine, nanotechnology, etc., can solve the problems of inability to cross the blood-brain barrier, cumbersome preparation process, and limited application, and achieve low cost, great application prospects, and improved drug quality. effective effect
Inactive Publication Date: 2017-12-15
CENT SOUTH UNIV
View PDF2 Cites 11 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
However, the neuroprotective molecules that have been developed that integrate metal chelating and antioxidant properties cannot cross the blood-brain barrier (BBB)
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0040] The present invention will be further described below in conjunction with specific examples. These examples should be understood as only for illustrating the present invention but not for limiting the protection scope of the present invention. After reading the contents of the present invention, various changes or modifications made to the present invention based on the principles of the present invention also fall within the scope of the claims of the present invention.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more PUM
Property | Measurement | Unit |
---|---|---|
Thickness | aaaaa | aaaaa |
Diameter | aaaaa | aaaaa |
Login to view more
Abstract
The invention discloses a black phosphorus nano material for treating Alzheimer's disease, wherein a black phosphorus nanosheet is prepared from black phosphorus powder by an ultrasonic liquid peeling process. Moreover, the invention also discloses a preparation method and application of the nano material. According to the invention, the black phosphorus nanosheet for treating Alzheimer's disease can be used as a nano acquirer for effectively and selectively acquiring Cu<2+>, so as to reduce generation of active oxygen in cells and protect the cells from the toxicity related to non-dynamic balance of the Cu<2+>. According to the black phosphorus nanosheet medicine for treating Alzheimer's disease disclosed by the invention, the blood-brain barrier permeability can be improved through a photothermal effect, the shortcomings that a small-molecule compound or polypeptide cannot pass through blood-brain barrier and is unstable are overcome, and the efficacy is improved. The nanomaterial has the advantages of simple preparation process, no additional drug load, high stability and high biocompatibility, and thus has excellent biosecurity when used for treating Alzheimer's disease.
Description
technical field [0001] The invention belongs to the field of preparation of medical materials; in particular, it relates to the application of black phosphorus nanosheets in the preparation of nanomedicine for treating Alzheimer's disease. Background technique [0002] Black phosphorus, as a new type of layered material, is called phosphorene because of its crystal structure similar to graphene, and has received extensive attention in the past few years. It is a honeycomb wrinkled structure, and the van der Waals force between layers is relatively weak, and single-layer nanosheets can be obtained by ultrasonic stripping. Unlike graphene, the energy bandgap of black phosphorus nanosheets (BP) is related to its thickness. The energy bandgap of bulk BP is about 0.3eV, while that of single-layer BP nanosheets is 2.0eV. In addition, because BP nanosheets have high electron mobility, planar anisotropy, and can absorb wavelengths from ultraviolet to the entire visible range, they ...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more Application Information
Patent Timeline
Login to view more
IPC IPC(8): A61K41/00A61K33/42A61P25/28B82Y5/00
CPCA61K33/42A61K41/0052B82Y5/00
Inventor 邓留徐群芳陈万松欧阳江刘又年
Owner CENT SOUTH UNIV
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Try Eureka
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap