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Formula and application of a preparation for regulating intestinal microecology

A micro-ecological preparation and a technology for regulating the intestinal tract, which can be used in applications, pharmaceutical formulations, food forming, etc., and can solve the problems of not finding patients with combined diarrhea

Active Publication Date: 2018-08-03
房学迅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are compound formulas on the market that use Pueraria root, ginseng, inulin, and cereal ingredients barley, oats, corn, soybeans, etc., which are used for both medicine and food. There are also products using probiotics as the main raw material, but no combination of diarrhea has been found. The physical characteristics of the patient, based on the essence theory of traditional Chinese medicine and the research results of modern intestinal microecological regulation, the golden combination is made of a variety of traditional Chinese medicines for both medicine and food, a variety of probiotics, prebiotics, and a variety of grain fibers as the main raw materials medical formula food, specific medical formula food or similar products

Method used

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  • Formula and application of a preparation for regulating intestinal microecology
  • Formula and application of a preparation for regulating intestinal microecology
  • Formula and application of a preparation for regulating intestinal microecology

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Formulated according to the following weight fractions, weigh the freeze-dried probiotic freeze-dried powder, which contains Lactobacillus rhamnosus, Lactobacillus salivarius, Lactobacillus plantarum, Lactobacillus reuteri, Lactobacillus bulgaricus, Lactobacillus fermentum, cheese milk Bacillus, Lactobacillus paracasei and Bifidobacterium animalis. Make the number of viable probiotic bacteria in the final system 10 10 CFU / g. Weigh 32.88% of kudzu root, 25.97% of inulin, 6.55% of ginseng, 1.44% of turmeric, 7% of puffed barley powder, 2.71% of puffed oat powder, 2% of puffed corn powder, and 2% of puffed soybean powder. Weigh the 80-mesh-100-mesh powder of each component according to the above ratio, add binder hydroxypropyl cellulose, mix evenly, add appropriate amount of distilled water to moisten, and use wet granulation to make granules. The prepared granules are vacuum-packed, 2.4 g per package. After opening the vacuum aluminum foil bag, pour the contents direc...

Embodiment 2

[0041] Or according to the number of live probiotics in the final system 10 9 CFU / g, kudzu root 39.16%, inulin 34.07%, ginseng 3.89%, turmeric 0.86%, barley 7.71%, oat 3.71%, corn 2%, soybean 2%, made into granules, or directly used in vacuum packaging in the form of powder .

[0042] Vacuum packaging of the prepared granule morphology and products such as figure 1 , figure 2 shown.

Embodiment 3

[0044] The application of the preparation for regulating intestinal microecology in animal diarrhea comprises the following steps.

[0045] Construction of experimental animal diarrhea model: 30 mice of 18-22 g were selected. The model animals were randomly divided into three groups (normal group, medication group, and model control group), among which the medication group and negative control group were used to model the diarrhea model. The mice were fasted for 4 hours, and each mouse was fed with 0.2-0.3 mL of castor oil, and then placed in a single cage with filter paper or ordinary white absorbent paper placed under the cage net. Observe the number of points that the mice get rid of rotten stools and loose stools within a certain period of time.

[0046] After obvious diarrhea symptoms appeared, the intestinal microecological regulators obtained in the above-mentioned Example 1 or Example 2 were respectively dissolved in sterile distilled water, and the mice in the admini...

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Abstract

The invention belongs to the technical field of medicine and food homologous formula and new resource food, and specifically provides food for patients with intestinal microecological disorder, medical formula food, specific medical formula food, health care products and medicines. The formulation of the intestinal microecological regulation preparation is combined with the physical characteristics of the intestinal microecological disturbance population, and is reasonably compatible according to the essence theory of traditional Chinese medicine and the progress of modern biological science. Specifically, the vacuum freeze-dried probiotic powder, supplemented with multiple natural plant essences such as prebiotics, grain fiber, and traditional Chinese medicines and traditional Chinese medicines, is made by mixing and granulating processes to effectively form a probiotic intestinal barrier, Intestinal microecological regulation preparation for promoting yang, invigorating the spleen, regulating the middle, anti-inflammation, relieving pain and dispelling damp-heat. The intestinal microecological adjustment preparation can effectively improve gastrointestinal diseases such as diarrhea, enteritis and indigestion caused by intestinal microecological disturbance; at the same time, the tranquilizing effect of ginseng can effectively improve insomnia and dreaminess; kudzu root and turmeric can relieve alcohol and protect the liver Effectively protect the liver and relieve discomfort after drinking.

Description

technical field [0001] The invention belongs to the technical field of medicine and food homologous formula and new resource food. Specifically, it involves a combination of the physical characteristics of people with intestinal microecological disorders, according to the rational compatibility of the essence theory of traditional Chinese medicine and the progress of modern biological science, the combination of multiple natural plant essences such as traditional Chinese medicine, probiotics, prebiotics and grains Reasonably matched to make intestinal microecological adjustment food, special medical formula food, medical formula food, health care products and medicines. The intestinal microecological adjustment preparation can relieve diarrhea and enteritis, and at the same time protect the liver and lower blood lipids , Promote sleep. Background technique [0002] There is a symbiotic relationship between the intestinal microecology and the human body, and it is an indispe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P1/00A61P1/04A61P1/12A61P1/16A61P3/06A61P25/20A23L33/10A23L33/135A23L33/22A23L7/10A23L11/00A23P10/20A61K31/733A61K35/745A61K35/747
CPCA61K36/899A61K36/8994A61K36/9066A23L7/10A23L11/05A23L33/10A23L33/135A23L33/22A23P10/20A61K31/733A61K35/745A61K35/747A61K36/258A61K36/48A61K36/488A23V2002/00A61K2300/00A23V2200/32A23V2200/3204A23V2200/334
Inventor 房学迅于大海杨吉雨
Owner 房学迅