Full-degradable metal-based vascular tissue closure clamp for endoscope

Abstract

The invention discloses a full-degradable metal-based closure clamp. The full-degradable metal-based closure clamp is applicable to closing blood vessels or tubular tissues in an endoscope operation.The full-degradable metal-based closure clamp has the following advantages that the closure clamp is made of degradable pure magnesium or magnesium alloy; the closure clamp is of a V-shaped structure,and an upper arm and a lower arm of the closure clamp are connected through an arc tail for removing stress concentration; the head of the upper arm and the head of the lower arm of the closure clampare provided with closing-locking structures which achieve the closing effect; the head and shoulder of the upper arm and the head and shoulder of the lower arm of the closure clamp are provided withclamping structures which are matched with clamp-application pincers; clamping teeth which can be cooperatively closed are arranged on a clamping surface of the closure clamp body. When the clamp-application pincers clamp and close the closure clamp, the upper arm elastic structure of the closure clamp is in contact with the lower arm structure to form closure, and the matched clamping teeth on the clamping surface are closely attached to blood vessels/tissues to make the lumens closed. Due to the closure mode of the closure clamp for the blood vessels/tissues and the degradability and mechanical properties endowed by magnesium-based materials, the closing capability is high, the clamp does not easily shed, body fluid is completely degraded, and clinic requirements can be well met.

Description

technical field [0001] The invention discloses a fully degradable metal-based blood vessel / tissue closure clamp, in particular an instrument suitable for clamping blood vessels or tubular tissues in laparoscopic surgery, belonging to the field of medical instruments. Background technique [0002] Today, as a minimally invasive surgical technique, laparoscopic technology has achieved revolutionary success in more and more traditional surgical fields, and has become the main theme of global surgical development. However, in the current minimally invasive surgical operation, the intracavity lumen will inevitably produce bleeding during the intracavitary operation, and the necessary hemostatic treatment should be performed in time. In traditional surgery, the hemostatic closure of such luminal structures is ligated with sutures, but it takes a long time to operate and often requires a large incision to assist. In laparoscopic surgery, the use of such sutures is more effective I...

AI Technical Summary

Problems solved by technology

However, these three types of closure clips all have certain disadvantages: 1. For example, metal titanium clips can cause great damage to vascular tissue, and excessive clipping can cause blood vessel cutting; the ligature nails are retracted in the clamp, and the ligature nails are easy to slide , prolapse; Structurally speaking, the clip is rigid and the ligation range is narrow; there is no tactile closing device; MRI and CT examinations have artifacts and deflection

2. If the non-absorbable polymer closure clip exists permanently in the body, the foreign body reaction is relatively large; and the polymer strength is not enough. In order to ensure sufficient strength, the product volume is generally large, and it will affect the local tissues of the human body after being placed. Poor flexibility, prone to slipping after clamped lumen or tissue edema subsides

3. For example, absorbable polymer closure clips, the current mainstream closure clip products are Tyco’s Lapro-clip and Johnson & Johnson’s Absolock, the former is made of polyglycol carbonate, and the latter is made of polydioxanone polyester, both of which are made of Composed of degradable materials, the degradation time is 6-7 months, which can avoid the long-term foreign body reaction of the permanent closure clip, but it also has the problem of large volume, which affects the internal tissues of the human body after implantation; in addition, Lapro-clip has no effect on hardened The closing ability of the blood vessel or tissue is weak, or even cause the clip body to break, and the closure needs to be completely covered with the lumen for ligation, which is not conducive to the ligation of the blood vessel or tissue that is not completely free. At the same time, the blood vessel or tissue will be squeezed out during the closing process. Pressure, resulting in weak closure; Absolock is easy to soften rapidly when it encounters body fluids, and the closing force is not strong

Chinese patent CN 201120412587.9 discloses a U-shaped absorbable magnesium alloy tissue closure clip, and CN201510808275.2 discloses a V-shaped absorbable magnesium alloy laparoscopic hemostatic clip. The structure of these two types of closure clips is similar to that of traditional titanium clips. However, because the mechanical strength and plasticity of magnesium-based materials are far inferior to those of titanium alloy materials, such a structure may not be tightly sealed, and the rigid structure of the clip body may have a risk of root fracture failure when it is deformed.

CN 201310451057.9 discloses a V-shaped or U-shaped magnesium-based metal tissue clip with a self-locking structure. The clip includes a mother arm, a self-locking arm and a child arm. The mother arm and the child arm form a V-shaped or U-shaped structure. The rack on the self-locking arm connected by the first section of the arm is connected with the acute angle structure of the sub-arm section to form a closure. The processing and closing operation are relatively complicated, and the reliability of the closure is open to question.

Patent CN 201420187862.5 discloses a degradable and absorbable metal vascular clip with a locking structure. The vascular clip includes upper and lower arms and a tail O-shaped structure for closing blood vessels, and the lower arm is provided with a groove as an elastic structure (accompanying drawing Explain 0024 structure 7), when the blood vessel clamp is closed in an arc shape, the uneven closing force may easily cause deformation of the lower arm fixing structure (0024 structure 10) and turn away from the closing direction, resulting in closure failure

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