A kind of extract for treating constipation and preparation method thereof

A technology for treating constipation and extracts, applied in the field of extracts for treating constipation and its preparation, can solve problems such as endocrine disorders, aggravated constipation, drug dependence, etc., and achieve the effect of treating constipation

Inactive Publication Date: 2020-11-17
贵州拜特制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, using Kaisailu treats the symptoms but not the root cause, while using Western medicine, if taken for a long time, will produce drug dependence, induce constipation, and cause endocrine disorders, premature aging
At present, some of the traditional Chinese medicine prescriptions for treating constipation are bitter and cold in nature, which can easily hurt people's stomach qi, and make the digestion and absorption function decline, which not only affects the curative effect, but also produces side effects

Method used

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  • A kind of extract for treating constipation and preparation method thereof
  • A kind of extract for treating constipation and preparation method thereof
  • A kind of extract for treating constipation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Recipe: 621g honeysuckle, 442g flavescens, 77g cork, 233g gallnut, 314g each of cnidium and sweet potato vine

[0023] Preparation Process:

[0024] 1) Grind honeysuckle and flavescens into coarse powder, pass through a 20-mesh sieve, add 6 times the amount of 70% ethanol to soak for 3 hours, heat and reflux 3 times, each extraction time is 4 hours , the amount of ethanol used for the second and subsequent times is 7 times the weight of the medicinal materials, filtered, combined filtrates, concentrated to a relative density of 1.10-1.30 at 50-70 ° C, and vacuum-dried to obtain an extract for use.

[0025] 2) Sliced ​​cnidium fruit and sweet potato vine, add 7 times the amount of 80% ethanol, heat and reflux 3 times, each extraction time is 4 hours, filter, combine the filtrate, concentrate the filtrate to an extract with a relative density of 1.10-1.25, and obtain The ethanol extract is used for later use; collect the dregs, add 5 times the amount of water to the dreg...

Embodiment 2

[0029] Recipe: 200g honeysuckle, 100g flavescens, 30g cork, 90g gallnut, 100g each of cnidium and sweet potato vine

[0030] Preparation Process:

[0031] 1) Grind honeysuckle and flavescens into coarse powder, pass through a 20-mesh sieve, add 5 times the amount of 60% ethanol to soak for 2 hours, heat and reflux twice, each extraction time is 2 hours, the amount of ethanol used for the second and subsequent times 5 times the weight of the medicinal material, filter, combine the filtrates, concentrate the filtrates to a relative density of 1.10-1.30 at 50-70°C, and vacuum-dry to obtain an extract for use.

[0032]2) Fructus Cnidii and sweet potato vine slices, add 5 times the amount of 70% ethanol, heat and reflux twice, each extraction time is 2 hours, filter, combine the filtrate, concentrate the filtrate to an extract with a relative density of 1.10-1.25, and obtain The ethanol extract is used for later use; collect the dregs, add 3 times the amount of water to the dregs,...

Embodiment 3

[0036] Recipe: 700g honeysuckle, 500g flavescens, 80g cork, 300g gallnut, 400g each of cnidium and sweet potato vine

[0037] Preparation Process

[0038] 1) Crush honeysuckle and flavescens into coarse powder, pass through a 20-mesh sieve, add 8 times the amount of 85% ethanol to soak for 4 hours, heat and reflux 4 times, each extraction time is 5 hours, the amount of ethanol used for the second and subsequent times 8 times the weight of the medicinal material, filter, combine the filtrates, concentrate the filtrate to a relative density of 1.10-1.30 at 50-70°C, and vacuum-dry to obtain an extract for use.

[0039] 2) Sliced ​​cnidium fruit and sweet potato vine, add 8 times the amount of 90% ethanol, heat and reflux 4 times, each extraction time is 5 hours, filter, combine the filtrate, concentrate the filtrate to an extract with a relative density of 1.10-1.25, and obtain The ethanol extract is used for later use; collect the dregs, add 6 times the amount of water to the d...

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Abstract

The invention discloses an extract for treating constipation. The extract is prepared from the following medicines in parts by weight: 200 to 700 parts of honeysuckle stem, 100 to 500 parts of lightyellow sophora root, 30 to 80 parts of cortex phellodendri, 90 to 300 parts of Chinese gall, 100 to 400 parts of common cnidium fruit and 100 to 400 parts of digua fig stem and leaf. Active ingredientsof the extract are ethanol extracts of the honeysuckle stem and the lightyellow sophora root, an ethanol-water extraction mixture of the common cnidium fruit and the caulis fici tikouae and ethanol extracts of the cortex phellodendri and the Chinese gall. The extract is prepared by the scientific concerted application of the six traditional Chinese medicines, all the traditional Chinese medicineshave a synergistic effect, the exerted effect is multiplied, the extract has the characteristics of simple formula and outstanding efficacy, and in an application experiment on patients, the remarkable efficacy of the extract in treating constipation is discovered in the process of treating haemorrhoids.

Description

technical field [0001] The invention relates to the field of medicine preparation, in particular to an extract for treating constipation and a preparation method thereof. Background technique [0002] Constipation-prone groups include the elderly, pregnant women, infants and young children. The degree can be mild or severe, and it can be temporary or long-term in time. There are many and complicated reasons for constipation, including the following factors: age, bad living habits, including eating low-residue and refined food, or a simple diet, lack of crude fiber, which reduces the volume of stool and increases its viscosity. Intestinal motility slows down, excessive water absorption leads to constipation, failure to develop the habit of regular defecation, often ignoring normal bowel movements, resulting in suppressed defecation reflex and causing constipation, certain diseases and obesity factors, resulting in decreased activity, especially due to Patients who are bedrid...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/756A61P1/10A61K35/64
CPCA61K35/63A61K36/234A61K36/355A61K36/489A61K36/60A61K36/756A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 薛捷张庆捷李白玲戴奕馨陈娟张程益
Owner 贵州拜特制药有限公司
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