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Transdermal drug delivery product for breast disease and preparation method of product

A technology for skin drug delivery and breast disease, which is applied in the field of transdermal drug delivery products for breast disease and its preparation, can solve the problems of limited patient types, no safe and effective external medicine, unsuitable oral medicine, etc. Toxic and side effects, avoiding the destruction of effective substances and the generation of toxic substances, and the effect of not being resistant to drug resistance

Inactive Publication Date: 2018-02-09
中山市择朋生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Most of the existing treatment options are oral medicine, and surgery is used in severe cases; however, for some special groups, such as breastfeeding women and the infirm, oral medicine is not suitable; surgical treatment is more suitable for patients because of its large damage
There is no safe and effective external drug

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0092] Example 1. No. 1 product for mastopathy

[0093] Raw materials with good ratio: Motherwort 15, Salvia 8, Angelica 12, Chuanqiong 15, Safflower 12, Cinnamon 11, Eupatorium 12, Citrus aurantium 8, Citrus aurantium 10, Huanglian 15, Phellodendron 8, Scutellaria baicalensis 15, Habitat 12, mountain edge 8, curcuma 12, mountain arrowhead mushroom 8, bamboo yellow 8, houttuynia cordata 15, money grass 12, hedyotis diffusa 12, barbata 8, lobelia 15, flea 8, star anise gold plate 12 , silkworm 12, dried earthworm 15, ginger peel 3, wax gourd peel 8, mulberry leaves 5;

[0094] Step 1. Water is inactivated in an ultra-high pressure cooker at 30°C and 600mpa for 10 minutes. After completion, 19 liters of it are injected into a sterile fermenter through a sterile silica gel pipeline for later use.

[0095] Step 2. Extract the water extract of traditional Chinese medicine:

[0096] The well-proportioned raw materials are packed in a 100-mesh filter, and the hydrogen-rich water an...

Embodiment 2

[0104] Example 2. No. 2 product for mastopathy

[0105] Good ratio of raw materials 2: motherwort 8, salvia miltiorrhiza 15, angelica 15, Chuanqiong 8, safflower 15, cinnamon 8, euphemum 15, aurantium aurantium 12, aurantium aurantium 15, yellow lotus 12, phellodendron 15, scutellaria baicalensis 12, Habitat 8, Mountain Edge 15, Curcuma 15, Shanzi Mushroom 8, Bamboo Yellow 13, Houttuynia cordata 12, Desmodium 15, Hedyotis diffusa 8, Scutellaria barbata 12, Lobelia 12, Flea 12, Star anise gold plate 8, 15 stiff silkworms, 8 dried earthworms, 5 ginger peels, 3 wax gourd peels, 8 mulberry leaves;

[0106] Step 1. Water is inactivated in an ultra-high pressure cooker at 25°C and 600mpa for 5 minutes. After completion, 10 liters of it are injected into a sterile fermenter through a sterile silica gel pipeline for later use.

[0107] Step 2. Extract the water extract of traditional Chinese medicine:

[0108] The well-proportioned raw materials are packed in a 100-mesh filter, and ...

Embodiment 3

[0116] Example 3. No. 3 product for mastopathy

[0117] Good ratio of raw materials 3: motherwort 13, salvia miltiorrhiza 12, angelica 8, Chuanqiong 12, safflower 8, cinnamon 15, euphemum 8, aurantium aurantium 15, aurantia citrus 12, yellow lotus 8, phellodendron 12, scutellaria baicalensis 12, Habitat 15, Mountain Edge 12, Curcuma 8, Shanzi Mushroom 15, Bamboo Yellow 15, Houttuynia cordata 8, Desmodium 8, Hedyotis diffusa 15, Scutellaria barbata 15, Lobelia 8, Flea 15, Star anise gold plate 15, silkworm 8, dried earthworm 12, ginger peel 4, wax gourd peel 4, mulberry leaves 3;

[0118] Step 1. Hydrogen-rich water (Hitian Tianling water) is inactivated in an ultra-high pressure cooker at 28°C and 600mpa for 7 minutes. After completion, 25 liters of it are injected into a sterile fermenter through a sterile silica gel pipeline for later use.

[0119] Step 2. Extract the water extract of traditional Chinese medicine:

[0120] The well-proportioned raw materials are packed in ...

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PUM

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Abstract

The invention relates to a transdermal drug delivery product for the breast disease and a preparation method of the product and belongs to the field of traditional Chinese medicines. The transdermal drug delivery product is prepared from water extracting solutions of raw materials and mother strain stock solutions of black fungus and morchella vulgaris through co-fermentation, wherein the raw materials comprise, in parts by weight, 10 parts of herba leonuri, 10 parts of radix salviae miltiorrhizae, 10 parts of radix angelicae sinensis, 10 parts of rhizoma chuanxiong, 10 parts of flos carthami,10 parts of cortex cinnamomi, 10 parts of herba lycopi, 10 parts of fructus aurantii immaturus, 10 parts of fructus aurantii, 10 parts of rhizoma coptidis, 10 parts of cortex phellodendri, 10 parts of radix scutellariae, 10 parts of radix rehmanniae, 10 parts of rhizoma sparganii, 10 parts of rhizoma curcumae, 10 parts of pseudobulb of appendiculate cremastra, 10 parts of herb of tabasheer, 10 parts of herba houttuyniae, 10 parts of herba desmodii styracifolii, 10 parts of herba hedyotis diffusae, 10 parts of herba scutellariae barbatae, 10 parts of herba lobeliae chinensis, 10 parts of manyleaf paris rhizome, 10 parts of fatsia japonica, 10 parts of stiff silkworms, 10 parts of dried earthworms, 5 parts of fresh ginger peels, 5 parts of wax gourd peels and 5 parts of mulberry leaves. Thewater solutions of the raw materials use hydrogen water as an extracting solvent. The product is used for treating the breast disease, has a good curative effect and no toxic or side effects, is convenient to use and can timely relieve the disease progression, improve the immunity of patients and remarkably improve the survival quality of the patients.

Description

technical field [0001] The invention relates to a traditional Chinese medicine product and its processing technology, in particular to a percutaneous drug delivery product for mastopathy and a preparation method thereof. technical background [0002] Breast disease usually presents as breast pain and lumps in the breast. Breast pain is mostly caused by mastitis, which occurs during breastfeeding, showing distending pain or pulsating pain, accompanied by redness, swelling, and heat. Breast epithelial hyperplasia should be considered if one side of the breast presents intermittent diffuse dull pain, cluster pain, or localized dull pain and tingling pain, which is related to menstrual cycle and emotional changes. In the late stage of breast cancer, severe pain in the breast may also occur due to the lesion invading the nerve. Cystic hyperplasia of the breast, breast tuberculosis, breast tuberculosis, breast fibroadenoma, and early breast cancer may all have lumps in the breas...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P15/14A61K35/62A61K35/64
CPCA61K9/0041A61K35/62A61K35/63A61K36/062A61K36/185A61K36/232A61K36/236A61K36/25A61K36/286A61K36/34A61K36/42A61K36/53A61K36/533A61K36/537A61K36/539A61K36/54A61K36/605A61K36/718A61K36/748A61K36/752A61K36/756A61K36/78A61K36/804A61K36/896A61K36/898A61K36/902A61K36/9066A61K36/9068A61K2236/19A61K2236/331A61K2236/51A61K2236/53A61K2300/00
Inventor 彭鹏李泽文郑永琴彭都
Owner 中山市择朋生物科技有限公司