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Medical composition capable of repairing damaged skin as well as preparation method and application of medical composition

A composition and drug technology, applied in the direction of drug combination, skin diseases, pharmaceutical formulations, etc., can solve the problems of affecting damaged skin function, difficult wound healing, and delayed wound healing time, so as to speed up wound healing and repair damage Effect of skin, strong application value

Pending Publication Date: 2018-06-01
中山瑞德生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, many factors (such as venous or arterial occlusion, diabetes, kidney disease, old age, tissue hypoxia, ischemia, infection or immune compromise, etc.) can lead to the interruption of the wound healing process, making the wound healing time delayed, or even difficult to heal the wound , thereby affecting the recovery of damaged skin function

Method used

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  • Medical composition capable of repairing damaged skin as well as preparation method and application of medical composition
  • Medical composition capable of repairing damaged skin as well as preparation method and application of medical composition
  • Medical composition capable of repairing damaged skin as well as preparation method and application of medical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0033] Drug Prescription:

[0034]

[0035] Preparation method:

[0036] (1) Take Carbomer 940, add 50g of propylene glycol, stir evenly, add 150g of distilled water, and swell for 24 hours;

[0037] (2) Take hydrolyzed collagen and bletilla striata glue, add 500g of distilled water, fully dissolve, filter, and the filtrate is set aside;

[0038] (3) Get asiaticoside and azone, after mixing, add 50g propylene glycol to dissolve;

[0039] (4) Under the condition of constant stirring, slowly add the substance obtained in steps (2) and (3) and the nanosilver solution into (1), and stir for 30 minutes, so that the drug is fully and evenly dispersed in (1);

[0040] (5) After diluting the triethanolamine with water, slowly add it to (4), stir continuously to make it into a gel, add water to 1000g, and obtain the pharmaceutical composition of the present invention.

Embodiment 2

[0041] The preparation of embodiment 2 pharmaceutical compositions of the present invention

[0042] Take 10mL of nano-silver (2000ppm), 30g of hydrolyzed collagen (<3000 Daltons), 10g of bletilla striata gum, and 0.5g of asiaticoside, and add the above-mentioned raw materials into commonly used pharmaceutical excipients or auxiliary ingredients to prepare a gel.

Embodiment 3

[0043] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0044] Take 100mL of nano-silver, 80g of hydrolyzed collagen, 50g of bletilla striata gum, and 3g of asiaticoside, and add the above-mentioned raw materials to common pharmaceutical excipients or auxiliary ingredients to prepare a cream preparation.

[0045] Prove the beneficial effect of the present invention in the mode of experimental example below:

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PUM

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Abstract

The invention discloses a medical composition. The medical composition is a preparation prepared from the following components in parts by weight: 10 to 100 parts of nano-silver, 30 to 80 parts of hydrolyzed collagen, 10 to 50 parts of bletilla striata gelatin and 0.5 to 3 parts of asiaticoside. The invention further discloses a preparation method and application of the medical composition. The medical composition disclosed by the invention can be used for rapidly reducing a wound area of damaged skin, remarkably shortening scabbing, scab falling and wound healing time and accelerating skin wound healing speed; the medical composition can be used for effectively repairing the damaged skin and has relatively strong actual application value.

Description

technical field [0001] The invention relates to a pharmaceutical composition for repairing damaged skin. Background technique [0002] The skin is one of the main organs of the human body. Its tissue structure is complex and has a special two-way barrier function, which can not only protect various organs and tissues in the body from damage by external harmful factors, but also prevent the loss of water, electrolytes and nutrients in the body. Internal metabolic disorders of the human body and external environmental damage (such as physical, chemical, ultraviolet rays, rays, smog, abuse of skin care products, etc.) will destroy the skin structure and cause skin damage. Skin damage involves many skin diseases, mainly including burns, skin trauma, sunburn, tumor radiotherapy burns, laser surgery burns, skin bedsores, diaper dermatitis in children, skin herpes zoster, acne, etc. [0003] The key to repairing damaged skin is to promote the healing of skin wounds. The healing o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/39A61P17/02A61K33/38A61K36/898A61K31/7024
CPCA61K33/38A61K31/7024A61K36/898A61K38/39A61K2300/00
Inventor 赵斌刘敬李拥军谢彩玲熊文明王琼付凤明
Owner 中山瑞德生物科技有限公司
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