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Medical analgesic and hemostatic dressing for anesthesiology department and preparation method of medical analgesic and hemostatic dressing

A pain-relieving and bleeding-stopping, anesthesiology technology, applied in the field of medical anesthesia, can solve the problems of wound cleaning, difficulty in suturing, and anxiety of injured patients.

Inactive Publication Date: 2018-06-22
AFFILIATED YONGCHUAN HOSPITAL OF CHONGQING MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Bleeding trauma often brings strong pain to the injured, and the continuous pain makes the injured anxious, which will bring many difficulties to cleaning and suturing the wound

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0031] Preparation of the surface layer of the non-woven fabric: Put the fibers into a cotton blending machine for blending, then transport them to a carding machine to be carded into a fiber web, and then transport them to a needle punching machine for acupuncture to obtain the surface layer of the non-woven fabric;

[0032]Preparation of the water-absorbing intermediate layer: take modified chitosan and stir and disperse it in deionized water to obtain a modified chitosan suspension; take modified sepiolite and ultrasonically disperse it in deionized water, then add modified loofah and ultrasonically oscillate for 10 minutes , then stir and add the modified chitosan suspension, continue to stir for 1-1.5h, compact, vacuum-dry, and send it to an acupuncture machine for acupuncture to obtain a water-absorbing middle layer;

[0033] Preparation of functional bottom layer: Add hyaluronic acid into deionized water, stir to dissolve, and then dropwise add N-hydroxysuccinimide, 1-et...

Embodiment 1

[0037] Preparation of modified loofah: take the peeled and denucleated loofah and cut it into small pieces and put it in deionized water, heat and boil for 5 minutes, then take it out and vacuum dry it to a water content of 5%, and then transfer it to a plasma quartz reactor. Plasma treatment was carried out at normal temperature and pressure, 600V and 50mA for 5 hours to obtain loofah fibers; egg shells were cleaned and dried, and ground into powder, and 0.4g of egg shell powder was added to 10mL of 25% mass concentration In the acetic acid solution, stir at a speed of 200rpm for 3.5h to obtain a calcium liquid activator; add 8g of loofah fiber to every 100mL calcium liquid activator, and completely soak the loofah fiber in the calcium liquid activator for 4h, filter, and wash Until the filtrate is neutral, it is vacuum-dried at 53° C. to obtain the modified loofah.

[0038] Preparation of modified sepiolite: Add 5g of natural sepiolite powder per 100mL of distilled water, ul...

Embodiment 2

[0046] Preparation of modified loofah: take the peeled and denucleated loofah and cut it into small pieces, put it in deionized water, heat and boil for 5 minutes, take it out and vacuum dry it to a water content of 6%, then transfer it to a plasma quartz reactor. Under the conditions of normal temperature and pressure, 600V and 50mA, plasma treatment was carried out for 6 hours to obtain loofah fibers; egg shells were cleaned and dried, and ground into powder, and 0.4g of egg shell powder was added to 10mL of 25% mass concentration In the acetic acid solution, stir at a speed of 230rpm for 3h to obtain a calcium liquid activator; add 8g of loofah fiber in every 100mL of calcium liquid activator, and completely immerse the loofah fiber in the calcium liquid activator for 4h, filter, and wash until The filtrate was neutral, and was vacuum-dried at 53° C. to obtain modified loofah.

[0047] The preparation of modified sepiolite is the same as in Example 1.

[0048] Preparation ...

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PUM

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Abstract

The invention relates to the technical field of medical anesthesia, in particular to a medical analgesic and hemostatic dressing for anesthesiology department and a preparation method of the medical analgesic and hemostatic dressing. The dressing comprises a non-woven fabric surface layer, a water absorbing middle layer and a functional bottom layer from top to bottom, wherein the water absorbingmiddle layer is a compressed modified loofah sponge, and pores of the modified loofah sponge are filled with modified sepiolite and modified chitosan; the functional bottom layer is hydrogel doped with an analgesic. The preparation method of the dressing comprises the following steps: the functional bottom layer and the water absorbing middle layer are expanded and overlapped to be placed into a needling machine for needling, and then the non-woven fabric surface layer is placed on the water absorbing middle layer in an overlapping manner for needling. The medical analgesic and hemostatic dressing can stop bleeding rapidly, can also realize sedative and analgesic effects and has good biocompatibility and biodegradability.

Description

technical field [0001] The invention relates to the technical field of medical anesthesia, in particular to a medical analgesic and hemostatic dressing for the department of anesthesiology and a preparation method thereof. Background technique [0002] Regarding anesthesia technology, the earliest written record in the world is Mabo Decoction, which appeared in the Han Dynasty in my country, and was invented by Hua Tuo, a famous ancient Chinese surgeon and Chinese medicine scientist. Mabo Decoction is a traditional Chinese medicine decoction equivalent to the current oral general anesthesia. After oral administration, the patient loses skin sensation and facilitates the operation. Later, Western medicine invented various anesthetics, such as lidocaine, bupivacaine, procaine, etc., which are popular now. Anesthesia is a reversible functional inhibition of the central and peripheral nervous systems produced by drugs or other methods, which is mainly characterized by loss of s...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/18A61L15/40A61L15/42A61L15/44A61L15/62
CPCA61L15/18A61L15/28A61L15/40A61L15/42A61L15/44A61L15/62A61L2300/602A61L2300/622C08L5/08
Inventor 刘大为
Owner AFFILIATED YONGCHUAN HOSPITAL OF CHONGQING MEDICAL UNIV
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