Polyether ether ketone bone defect repair material and preparation method

Abstract

The invention belongs to a polyetheretherketone bone defect repair material and a preparation method thereof in the field of medical materials. The surface of the polyetheretherketone bone defect repair material has a micropore-nanopore multilevel hole structure, and is also loaded with simvastatin, Polylactic acid porous micromembranes and tobramycin microspheres. The present invention overcomes the defects of low bioactivity, no antibacterial effect and poor osseointegration ability with bone tissue in the existing polyether ether ketone bone defect repair materials, and the provided polyether ether ketone bone defect repair materials have good antibacterial properties performance and good osteogenic activity, and the preparation method of the polyetheretherketone bone defect repair material provided has simple process and low cost.

Description

technical field

[0001] The invention belongs to the field of medical materials, and in particular relates to a polyether ether ketone bone defect repair material and a preparation method. Background technique

[0002] Bone defects caused by congenital deformities and injuries are still a difficult problem in basic research and clinical treatment in the fields of orthopedics, oral and maxillofacial surgery, and neurosurgery. The special engineering plastic polyetheretherketone (PEEK) has become the most promising hard tissue repair material that can replace traditional metal medical materials due to its excellent mechanical properties, chemical stability and biocompatibility. But the fatal point is that PEEK is a biologically inert material, and its osseointegration with bone tissue is poor, which limits its application in the field of hard tissue repair to a certain extent. On the other hand, the surface of the implant material is likely to cause bacterial adhesion and biof...