Streptomycin bactericide and preparation method thereof

Abstract

The invention discloses streptomycin bactericide and a preparation method thereof, and belongs to the field of plant bactericide. Streptomycin sulphate is used as raw medicine to be compounded with active ingredients A and B; a good cooperated effect is achieved, so that the sterilization efficiency is improved; the bacteriocidal spectrum is expanded; in addition, the fungus disease can be treated; pathogenic bacteria are difficult to generate medicine resistance. Firstly, nanometer silver particles and some protein molecules on the surface of bacteria are specifically combined; a phospholipidbimolecular layer structure is changed; the membrane permeability improvement is caused; the membrane fracture is even caused; the bacterium inhibition effect of terpene compounds, volatile oil, flavone compounds and the like contained in the active ingredient B can be obviously improved; the bacterium death is further caused. The streptomycin bactericide solves the problems that the existing bactericide has the single sterilization effect site, pathogenic bacteria can easily generate adaptative variation on the medicine; the medicine prevention and control effect reduction or failure can becaused; the bacterium disease is prevented and controlled; the fungal disease cannot be simultaneously treated.

Description

technical field [0001] The invention belongs to the field of plant fungicides, in particular to a streptomycin fungicide and a preparation method thereof. Background technique [0002] Streptomycin fungicide belongs to one of the products of plant fungicides. Streptomycin is an aminoglycoside antibiotic. Its mechanism of action is to act on ribosomes in bacteria, inhibit bacterial protein synthesis, and destroy the integrity of bacterial cell membranes. Susceptible bacteria have an oxygen-dependent antibiotic transmembrane transport system. Streptomycin can first pass through the outer membrane porin through passive diffusion, and then enter the cell through this transport system through the cell membrane, and irreversibly bind to the isolated ribosomal 30S subunit On, leading to the destruction of the A position, thereby preventing the correct positioning of the aminoacyl tRNA at the A position, interfering with the assembly of functional ribosomes, and inhibiting the for...

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention: in view of the single bactericidal action site of the current fungicides, the pathogens are prone to adaptability to the medicaments, resulting in reduced or even ineffective control effects of the bactericides. While preventing and treating bacterial diseases, fungal diseases cannot be treated at the same time The problem of providing a kind of preparation method of streptomycin fungicide