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A kind of traditional Chinese medicine preparation for treating hemorrhoids and its preparation method

A technology of traditional Chinese medicine preparations and hemorrhoids, applied in the field of traditional Chinese medicine preparations and preparations for treating hemorrhoids, can solve the problems of long treatment cycle, short treatment cycle, unsatisfactory effect, etc., achieve convenient administration, good treatment effect, and promote perianal physiological structure Recovery effect

Active Publication Date: 2021-10-01
荆州市致强生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] The object of the present invention is to aim at the problems in the prior art of recurrent hemorrhoids after treatment, long treatment cycle, unsatisfactory effect, and inconvenient use for patients; provide a kind of hemorrhoids mainly based on hirudin, supplemented by multi-flavored traditional Chinese medicine, Combining prescriptions based on traditional Chinese medicine theory, using modern preparation methods to make suppositories or gels, directly administering drugs to the affected parts, and targeting hemorrhoids to replenish qi and activate blood, clear heat and cool blood, promote dampness and detoxification, so as to achieve the treatment cycle Traditional Chinese medicine preparation for treating hemorrhoids with short, convenient use, small side effects and high bioavailability and preparation method

Method used

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  • A kind of traditional Chinese medicine preparation for treating hemorrhoids and its preparation method

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Experimental program
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Effect test

Embodiment a

[0050] Example a: Take 25g of hirudin, 5g of total alkaloid extract of Sophora flavescens, 3g of calcined borax, 2g of borneol, 64.5g of glyceryl stearate (type 36), and 0.5g of lecithin for later use. Put glyceryl stearate in a 500ml beaker, heat to 50°C-55°C to dissolve, put other raw materials into it, keep stirring until uniform, then fill it into a 1g suppository bag and shape it, and heat it at 5°C-55°C Store at 28°C.

Embodiment b

[0051] Example b: Hirudin 100g, Sophora flavescens total alkali extract 20g, calcined borax 12g, borneol 8g, glyceryl stearate (type 36) 258g, lecithin 2g. Put glyceryl stearate in a 500ml beaker, heat to 50°C - 55°C to dissolve, put other materials into it, keep stirring until uniform, then fill it into a 1g suppository bag to form, and put it at 5°C - Store at 28°C.

Embodiment c

[0052] Example c: 5 kg of hirudin, 1 kg of total alkali extract of Sophora flavescens, 0.6 kg of calcined borax, 0.4 kg of borneol, 12.9 kg of glyceryl stearate (type 36), and 0.1 kg of lecithin oil. Put glyceryl stearate in a 500ml beaker, heat to 50°C - 55°C to dissolve, put other materials into it, keep stirring until uniform, then fill it into a 1g suppository bag to form, and put it at 5°C - Store at 28°C.

[0053] Two, made into a gel:

[0054] Embodiment a: Hirudin 25g, Sophora flavescens total alkali extract 5g, calcined borax 3g, borneol 2g, 940 type carbomer 0.2g, triethanolamine 1.8g, methylparaben 0.4g, PEG-400 20g, water 142.6g spare. Fully dissolve the 940-type carbomer in water and let it stand for 12 hours, then dissolve hirudin, flavescens total alkaloid extract, calcined borax, and borneol in water and stir evenly, then pour it into the carbomer solution and stir, add Nepal gold methyl ester , PEG-400, add water to the specified amount, stir evenly, and ad...

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Abstract

The invention relates to a traditional Chinese medicine preparation for treating hemorrhoids and a preparation method, and belongs to the technical field of traditional Chinese medicine preparation. The present invention is divided into suppositories or gels, takes leech as the monarch drug, adopts freeze-drying process to obtain hirudin extract with high efficacy and activity, mainly attacks varicose veins at the bottom of anorectum and anal mucosa, and dissolves thrombus in perianal microvessels. Reduce local blood pressure and blood viscosity, so that the blood circulation of the diseased part is gradually restored; Sophora flavescens is used as a ministerial medicine, which has the effect of clearing away heat and dampness, and cooling blood; Calcined borax is used as an adjuvant to assist the monarch and minister medicines in clearing heat and eliminating heat. Swelling effect; borneol is used as the medicine to reconcile the various medicines, guide the various medicines to penetrate the skin and mucous membranes directly to the lesions, and make them work together to dispel pathogens. The invention applies medicine for perianal varicose veins, the direct cause of hemorrhoid formation, fundamentally improves the blood circulation of the lesions, promotes the recovery of perianal physiological structure, thus achieves the purpose of treating both the symptoms and the root causes, and reduces the recurrence probability of hemorrhoids. And the side effect is small, the use is safe, and the administration is convenient.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating hemorrhoids and a preparation method thereof, belonging to the technical field of traditional Chinese medicine preparation. Background technique [0002] Hemorrhoid is the unique common disease, frequently-occurring disease of the mankind. According to relevant census data, the incidence rate of anorectal diseases is 59.1%, and hemorrhoids account for 87.25% of all anorectal diseases, and among them, internal hemorrhoids are the most common, accounting for 52.19% of all anorectal diseases. Both men and women can get the disease, the incidence rate of women is 67%, and the incidence rate of men is 53.9%; it can occur at any age, and it is more common in people aged 20-40, and it will gradually increase with age, so there are "Nine hemorrhoids out of ten people" said. [0003] The soft vein group formed by the expansion and flexion of the venous plexus under the mucous mem...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/58A61P9/14A61K36/489A61K33/22A61K31/045
CPCA61K31/045A61K33/22A61K36/489A61K38/58A61P9/14A61K2300/00
Inventor 徐伟丁钊余涛龚元
Owner 荆州市致强生物科技有限公司
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