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32results about How to "Low probability of recurrence" patented technology

Immunochemotherapy pharmaceutical composition and preparation method therefor

The invention discloses an immunochemotherapy pharmaceutical composition. The immunochemotherapy pharmaceutical composition is formed by mixing a first mixture with a second mixture; the first mixturecontains immunoadjuvant imiquimod R837; the second mixture contains chemotherapeutic drug oxaliplatin which can cause immunogenicity death, and further contains poloxamer 188 and sodium alginate (ALG); the first mixture is an imiquimod emulsion obtained by mixing the imiquimod R837 with the poloxamer 188; imiquimod particles each have a particle size of 0.5-3 mum; the imiquimod emulsion undergoesmoist heat sterilization; and the second mixture is a mixture prepared in a manner that the sodium alginate (ALG) and the oxaliplatin are stirred and mixed with water, and filtration sterilization isperformed with a micrometer filter membrane. The new anti-cancer pharmaceutical composition can exert the synergistic anticancer effect, reduces the side effect, the cancer metastasis probability andthe cancer recurrence probability, and can inhibit the growth of a distant metastatic tumor and reduce the tumor recurrence probability through the immunoreaction while effectively killing a tumor insitu; and meanwhile, the production process is relatively optimal, and the product stability is high.
Owner:SUZHOU INNOVATIVE BIOMATERIALS & PHARM CO LTD

In-situ gelation chemotherapy and immunotherapy combined biopolymer pharmaceutical composition

The invention discloses an in-situ gelation chemotherapy and immunotherapy combined biopolymer pharmaceutical composition. The in-situ gelation chemotherapy and immunotherapy combined biopolymer pharmaceutical composition comprises a first component, a second component and a third component; the first component is alginate; the alginate can form porous gel with calcium ion in a body; the alginateis one or more of sodium alginate, potassium alginate and ammonium alginate; the second component is a chemotherapeutic drug capable of causing immungentic cell death; and the third component is an immunologic adjuvant. The in-situ gelation chemotherapy and immunotherapy combined biopolymer pharmaceutical composition belongs to a chemotherapy-immunotherapy pharmaceutical composition; therefore, anew anti-cancer pharmaceutical composition, which can take synergistic anticancer effect, reduce side effects, reduce the cancer metastasis probability and reduce the cancer recurrence probability, can be provided; and growth of a distal metastasis tumour and the tumour recurrence probability can be inhibited and reduced through immunoreaction while an in-situ tumour is killed effectively.
Owner:SUZHOU INNOVATIVE BIOMATERIALS & PHARM CO LTD

A kind of bactericidal skin care ointment for frostbite

The invention discloses sterilizing and skin-protecting chilblain cream, and relates to the technical field of daily-use chemical industry. The sterilizing and skin-protecting chilblain cream is prepared from the following raw materials in parts by weight: 2-7 parts of tea oil, 1-3 parts of tea seed cake, 0.5-2 parts of ginger, 35-60 parts of Vaseline, 0.1-2 parts of pepper, 0.5-2.5 parts of sinkiang arnebia root, 2-6 parts of towel gourd and 2.25-13.75 parts of purified water. A preparation method of the sterilizing and skin-protecting chilblain cream comprises the following steps: I, preparing a water extract: (1) preparing a filtrate A, (2) preparing a filtrate B, and (3) combining the filtrates; II, preparing powder; III, preparing a substrate; IV, preparing a finished product. The sterilizing and skin-protecting chilblain cream has the effects of cooling blood, activating blood, relieving swelling and pain, resisting bacteria, diminishing inflammation, removing freckle and wrinkle, preserving moisture, moistening and the like, can be used for treating chilblain, effectively relieving the skin problems of stain, redness and swelling, crack and the like, and treating and preventing chilblain, and is suitable for children, young people as well as middle aged and elderly people.
Owner:HUNAN XINJINHAO TEA OIL

Traditional Chinese medicine preparation for treating haemorrhoids and preparation method

The invention relates to a traditional Chinese medicine preparation for treating haemorrhoids and a preparation method, and belongs to the technical field of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is divided into a suppository and a gel. The preparation method comprises the following steps: using hirudo as a monarch drug, preparing a hirudin extract in high pharmacological activity by using a freeze-drying technology, mainly attacking the bottom of anorectum and varicosity of anal mucosa, dissolving thrombus in perianal microvessels, reducinga local blood pressure and a block viscosity, and enabling the blood circulation in a diseased region to be recovered gradually; using radix sophorae flavescentis as a ministerial drug, and achievingthe efficacy of clearing heat and drying dampness, and cooling blood; using calcined borax as an adjuvant drug, assisting the effects of clearing heat and swelling of the monarch drug and the ministerial drug; and using borneol as a conductant drug, coordinating the effects of the drugs, guiding the drugs to penetrate skin and mucosa and directly arrive a focus place, and enabling the drugs to eliminate evil cooperatively. The traditional Chinese medicine preparation is capable of administrating in allusion to a direct pathogeny of haemorrhoids formation which is the perianal varicosity, fundamentally improving the blood circulation of the focus place, promoting a perianal physiological structure to be recovered, thereby achieving a treatment purpose of treating both symptoms and root causes, and reducing a haemorrhoids relapse probability. In addition, the traditional Chinese medicine preparation is small in side effect, safe in use, and convenient in administration.
Owner:荆州市致强生物科技有限公司

Continuous nursing system for discharged depression patients

The invention relates to the technical field of depression nursing, and discloses a continuous nursing system for discharged depression patients. The system comprises a patient terminal and a nurse terminal bidirectionally connected with the patient terminal through the Internet. The patient terminal comprises a health archive module, a health education module, a medication management module, a health consultation module, an outpatient service reservation module and a satisfaction evaluation module, the health archive module comprises a health evaluation module and an evaluation report module, and the nurse terminal comprises a follow-up recording module and an information receiving and transmitting module. The health evaluation module comprises a risk evaluation unit, a data detection unit, a warning notification unit and an equipment monitoring unit. The psychological needs of the patient can be professionally concerned, the recurrence probability of the depression patient is reduced, the workload of nursing personnel is relieved, the timeliness and effectiveness of treatment of the depression patient are improved, and evidence-based medical evidence is provided for constructing a novel efficient continuous nursing mode.
Owner:苏州市广济医院

Spray for treating beriberi and extraction technology thereof

The invention discloses a spray for treating beriberi and an extraction technology thereof. The spray is prepared from the following raw materials of 30 to 50 parts of aloe, 25 to 35 parts of cotex dictamni, and 25 to 35 parts of radix sophorae flavescentis. The spray is prepared by the following steps of cleaning the raw materials, crushing, drying and sterilizing by infrared rays, grinding, screening, obtaining the matters under the sieve, and uniformly mixing; after uniform mixing, adding 10 to 20 times the weight of 75% ethyl alcohol, soaking for 15 to 30 days, and filtering, so as to obtain a filtrate; adding 0.05 to 0.2 time the weight of benzoic acid, uniformly mixing, and filtering again, so as to obtain the filtrate; separately filling into bottle, so as to obtain the spray. The spray has the advantages that the functions of sterilizing, resisting ulcer, promoting wound healing, caring skin, preventing odor, eliminating cutinization, softening scar and the like are realized; under the cooperation function with the cotex dictamni and the radix codonopsis, the anti-fungi effect is realized, the beriberi can be quickly treated, the injured skin is restored, the anti-bacterialability of the skin is improved, and the purpose of reducing the recurrence probability of beriberi is realized; any chemical component harmful to the body is not contained, any side effect is avoided, and the safety is high.
Owner:TAIYUAN AOYI MEDICAL BIOLOGICAL TECH

Traditional Chinese medicine composition with blood pressure reducing effect

The invention belongs to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition with a blood pressure reducing effect. The traditional Chinese medicine composition is characterized by comprising the following components in parts by weight: 12-15 parts of ligusticum wallichii, 6-12 parts of eucommia ulmoides, 7-12 parts of radix puerariae, 6-10 parts ofgynostemma pentaphylla, 4-8 parts of pinellia ternate, 5-12 parts of radix achyranthis bidentatae, 4-7 parts of fructus akebiae, 3-6 parts of fructus quisqualis, 3-9 parts of euphorbia kansui and 9-12 parts of rhizoma gastrodiae. The traditional Chinese medicines are crushed respectively and then are mixed and stirred according to the weight ratio until the traditional Chinese medicines are fullymixed, and after use, the blood pressure reducing effect is obvious.
Owner:罗运林

Externally-used medicine for treating stubborn ringworm and preparation method thereof

The invention discloses an externally-used medicine for treating stubborn ringworm and a preparation method thereof. The externally-used medicine comprises 2-3% of medicament and 97-98% of emulsifiable paste. The medicament comprises 2-methyl-5-nitroimidazole-1-ethanol, dexamethasone acetate, cyproheptadine hydrochloride, fluocinonide, miconazole nitrate, ketoconazole, clobetasol propionate, borneol and medical starch. Through scientific compatibility and mutual collaboration of the contents and proportions of all the components of the externally-used medicine for treating stubborn ringworm, the dosage is small, fungi can be quickly killed, itching is relived quickly, and stubborn ringworm is subjected to radical treatment; as for slight red and swollen symptoms cause by the fungi, itching is relived in the first day, the red and swollen symptoms disappear in the second day, and the color of the skin is changed; as for stubborn ringworm, such as psoriasis, existing for ages, the red and swollen symptoms are subsided within 3-5 days, after insistent applying for a month, reappearing of stubborn ringworm is avoided, and therefore radical treatment is achieved; and toxicity and irritation are small, dependence is avoided, the reappearing probability is small, the applicable range is wide, and the externally-used medicine can be used by pregnant women and children.
Owner:王昌华

Traditional Chinese medicine composition with blood pressure reducing function

The invention belongs to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition with a blood pressure reducing function. The traditional Chinese medicinecomposition is characterized by comprising the following components in parts by weight: 12-15 parts of cortex lycii radicis, 6-12 parts of peruvian groundcherry herb, 7-12 parts of lysimachia christinae hance, 6-10 parts of thesium chinense, 4-8 parts of semen cassiae, 5-12 parts of achyranthes bidentata, 4-7 parts of dogbane leaves, 3-6 parts of perilla leaves, 3-9 parts of burdock and 9-12 partsof monkshood. The traditional Chinese medicines are crushed respectively and then mixed and stirred according to the weight ratio until the traditional Chinese medicines are fully mixed, and after use, the blood pressure reducing effect is obvious.
Owner:罗运林

Traditional Chinese medicinal composition for treating skin diseases

The invention discloses a traditional Chinese medicinal composition for treating skin diseases. The traditional Chinese medicinal composition is characterized by consisting of a component A and a component B, wherein the component A is any one or any mixtures of radix paeoniae rubra, rhizoma chuanxiong, radix angelicae lateralis preparata, radix rehmanniae and flos carthami and the component B is any one or any mixtures of radix astragali, ginseng, honeysuckle flowers, radix scutellariae, cortex phellodendri, fructus forsythiae, sliced white aconite, cortex cinnamomi and radix rubiae. The traditional Chinese medicinal composition for treating the skin diseases provided by the invention is used for implementing treatment on the basis of the principle of treating blood before pathogenic wind and removing pathogenic wind by promoting circulation of blood in accordance with the theory of traditional Chinese medicine, 'eight-syndrome' differentiation of traditional Chinese medicine: yin, yang, exterior, interior, cold, heat, deficiency and excess, eight methods in traditional Chinese medicine treatment: warming, clearing, removing, reinforcing, perspiration, vomiting, purgation and alleviating, as well as the basic theory of meridian tropism of medicines. For different diseases in patients, different components of the traditional Chinese medicinal composition are adopted according to indications, so that a therapeutic effect is enhanced. In addition, on the basis of synergism and antagonism among the various medicines, a better curative effect can be achieved through actions among the medicines.
Owner:李炜

Traditional Chinese medicine for treating hypertension as well as preparation method and application thereof

The invention discloses a traditional Chinese medicine for treating hypertension as well as a preparation method and application thereof. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 4 to 5 parts of radix et rhizoma salviae miltiorrhizae, 4 to 5 parts of rhizoma gastrodiae, 4 to 5 parts of radix notoginseng, 4 to 5 parts of radix polygoni multiflori, 4 to 6 parts of fructus crataegi, 4 to 5 parts of cortex eucommiae, 4 to 6 parts of grape seed, 4 to 6 parts of fructus trichosanthis shell, 4 to 6 parts of fructus lycii, 4 to 6 parts of American ginseng and 3 to 6 parts of caterpillar fungus. The traditional Chinese medicine is derived from Yuexiangbi traditional remedy, has the effects of cleaning blood vessel garbage and plaques, softening blood vessels, repairing blood vessel injuries, lowering blood lipid, lowering blood pressure and is used for treating and preventing diseases including hypertension with coronary artery disease and the like; the traditional Chinese medicine has the effects of resisting oxidization, preventing cancer, lowering blood glucose and preventing vascular sclerosis. When being used for treating the hypertension, the traditional Chinese medicine has the characteristics of rapid effect, capability of treating both principal and secondary aspects of diseases, high healing rate, low recurrence rate, nodependence and low side effect.
Owner:赵文强

A kind of traditional Chinese medicine preparation for treating hemorrhoids and its preparation method

The invention relates to a traditional Chinese medicine preparation for treating hemorrhoids and a preparation method, and belongs to the technical field of traditional Chinese medicine preparation. The present invention is divided into suppositories or gels, takes leech as the monarch drug, adopts freeze-drying process to obtain hirudin extract with high efficacy and activity, mainly attacks varicose veins at the bottom of anorectum and anal mucosa, and dissolves thrombus in perianal microvessels. Reduce local blood pressure and blood viscosity, so that the blood circulation of the diseased part is gradually restored; Sophora flavescens is used as a ministerial medicine, which has the effect of clearing away heat and dampness, and cooling blood; Calcined borax is used as an adjuvant to assist the monarch and minister medicines in clearing heat and eliminating heat. Swelling effect; borneol is used as the medicine to reconcile the various medicines, guide the various medicines to penetrate the skin and mucous membranes directly to the lesions, and make them work together to dispel pathogens. The invention applies medicine for perianal varicose veins, the direct cause of hemorrhoid formation, fundamentally improves the blood circulation of the lesions, promotes the recovery of perianal physiological structure, thus achieves the purpose of treating both the symptoms and the root causes, and reduces the recurrence probability of hemorrhoids. And the side effect is small, the use is safe, and the administration is convenient.
Owner:荆州市致强生物科技有限公司

Biopsy needle and system

The invention discloses a biopsy needle and system. The biopsy needle comprises an inner tube, an outer telescopic piece, a tool bit and an electrode; the tool bit is arranged at the far end of the inner tube; the outer telescopic piece is configured to be arranged outside the inner tube in a sleeving mode and can be close to or away from the tool bit in the axial direction of the inner tube; one end of the electrode is connected with the tool bit, the other end of the electrode is connected with the far end of the outer telescopic piece, and the far end of the outer telescopic piece is the end, close to the tool bit, of the outer telescopic piece; in the process that the outer telescopic piece gets close to the tool bit in the axial direction of the inner tube, the electrode can be extruded to be bent outwards, and outward bending means that the electrode is bent away from the inner tube; and after the outer telescopic piece approaches the tool bit to a target position in the axial direction of the inner tube, the electrode is configured to rotate around the axial direction of the inner tube. According to the invention, sampling is carried out in a high-frequency electrotome rotary cutting mode, so that the problems of bleeding, complex structure, high cost and easy failure in the sampling of the existing physical cutting mode are solved.
Owner:上海修能医疗器械有限公司
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