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A kind of gel patch and preparation method thereof

A patch and gel technology, which is applied in the field of gel patch and its preparation, can solve the problems of complex gel components, gel adhesion performance and adverse effect effects, etc., to improve blood circulation and improve body immunity , the effect of protecting from damage

Active Publication Date: 2019-03-05
ZHUHAI GUOJIA NEW MATERIAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the above inventions, cross-linking regulators are added. The addition of cross-linking regulators not only makes the gel components more complicated, but if used improperly, it will adversely affect the adhesion performance and effect of the gel.

Method used

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  • A kind of gel patch and preparation method thereof
  • A kind of gel patch and preparation method thereof
  • A kind of gel patch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] 1) According to weight percentage, weigh 0.01% aloe extract, 0.01% lavender essential oil, 0.005% dipotassium glycyrrhizinate, 10% glycerin, 0.01% imidazolidinyl urea, 0.5% polyvinylpyrrolidone, 0.0001% essence, 0.0001% pigment, mix evenly, and stir for 4 minutes;

[0037] 2) Under stirring conditions, add 0.5% by weight of sodium polyacrylate with an average molecular weight of 2-3 million to step 1), continue stirring for 10 minutes, and then add 0.5% by weight of sodium polyacrylate with an average molecular weight of 80-1 million Sodium polyacrylate, 0.01% calcium sulfate and the rest of deionized water are stirred at 20°C at 10Hz to make gels. It is required to be uniform and free of gel, and the pH of the gel is 7.0;

[0038] 3) The gel obtained in step 2) is coated, shaped, punched, cut, inner packaged and outer packaged to obtain a gel patch.

Embodiment 2

[0040] 1) According to weight percentage, weigh 7% menthol, 1% borneol, 18% ethylene glycol, 2.0% phenoxyethanol, 3.0% hydroxyethyl cellulose, 0.02% essence, 0.02% Pigment, mix well, stir for 10 minutes;

[0041] 2) Under stirring conditions, add 6% by weight of sodium polyacrylate with an average molecular weight of 2-3 million to step 1), continue stirring for 10 minutes, and then add 2% by weight of sodium polyacrylate with an average molecular weight of 80-1 million Sodium polyacrylate, 0.2% calcium chloride and the rest of deionized water are stirred at 40°C and 40Hz to make gels. It is required to be uniform and free of gel, and the pH of the gel is 8.0;

[0042] 3) The gel obtained in step 2) is coated, shaped, punched, cut, inner packaged and outer packaged to obtain a gel patch.

Embodiment 3

[0044] 1) According to weight percentage, weigh 2.0% papaya extract, 1.0% lavender essential oil, 12% glycerin, 0.01% phenoxyethanol, 1.0% polyvinylpyrrolidone, 0.001% essence, 0.001% pigment, Mix well and stir for 5 minutes;

[0045] 2) Under stirring conditions, add 3% by weight of sodium polyacrylate with an average molecular weight of 2-3 million to step 1), continue stirring for 10 minutes, and then add 1% by weight of sodium polyacrylate with an average molecular weight of 80-1 million Sodium polyacrylate, 0.2% calcium chloride and the rest of deionized water are stirred at 30°C and 30Hz to make gels. It is required to be uniform and free of gel, and the pH of the gel is 7.5;

[0046] 3) The gel obtained in step 2) is coated, shaped, punched, cut, inner packaged and outer packaged to obtain a gel patch.

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Abstract

The invention discloses a gel patch and a preparation method thereof. Gel in the gel patch comprises effective components, sodium polyacrylate, a moistening agent, a cross-linking agent, a preservative, a thickening agent, essence and a pigment, wherein the average molecular weight of the sodium polyacrylate is 0.8-1 million and 2-3 million. When menthol is adopted as a main effective component, the gel patch with medical effects can be prepared, and the gel patch is capable of clearing heat and reducing temperatures, relieving symptoms such as fever, headache and dysphoria, protecting brain cells from being damaged and improving body immunity. Animal and plant extracts with unique effects of whitening skin, eliminating inflammation, relieving pain and the like are selected, and the gel patch which has the effects of whitening skin, removing beverages and scars, retaining skin moisture, making skin elastic, retarding skin aging, and the like, can be prepared. The gel patch disclosed bythe invention is convenient to use, can be clung to skin after the package is removed, and is free of irritation to skin.

Description

technical field [0001] The invention relates to the fields of medical equipment and cosmetics, in particular to a gel patch and a preparation method thereof. Background technique [0002] Gel patch is a new type of external application agent with high technology content, wide application range and convenient use in the world today. It belongs to the transdermal drug delivery system. External preparations made of cloth on non-woven fabrics. In the early 1970s, countries such as Japan and Europe began to develop medical gel patches. With the continuous development of the pharmaceutical industry, this new dosage form has developed in my country in recent years. Compared with the traditional rubber-type external plaster, the gel patch has the following advantages: it has good biocompatibility, affinity, air permeability, sweat resistance, and is not easy to be allergic to the skin; it uses a water-soluble macromolecular gel matrix , no residue after use, no pollution to clothe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/04A61K8/98A61F7/02A61K8/34A61K8/81A61K8/92A61K8/9706A61K8/9728A61K8/9771A61K8/9789A61K8/9794A61Q19/00A61Q19/02
CPCA61F7/02A61F2007/0219A61K8/042A61K8/34A61K8/8147A61K8/922A61K8/9706A61K8/9728A61K8/9771A61K8/9789A61K8/9794A61K8/981A61K8/987A61Q19/00A61Q19/02
Inventor 王海波王中元黄强
Owner ZHUHAI GUOJIA NEW MATERIAL
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