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A kind of traditional Chinese medicine composition and its preparation for treating myasthenia gravis
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A technology for myasthenia gravis, pharmaceutical preparations, applied in the field of biomedicine
Active Publication Date: 2021-10-22
乞国艳
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[0007] The research on the treatment of MG with traditional Chinese medicine has become a hot spot in the field of traditional Chinese medicine. Among them, the method of nourishing the spleen and nourishing the kidney occupies a certain proportion in the treatment of MD. A large number of clinical studies have confirmed that it can improve symptoms, reduce adverse reactions of hormones and immunosuppressants, reduce recurrence rate, It has shown its unique advantages in terms of improving the quality of life of patients, but at present there is still a need for an effective traditional Chinese medicine preparation for the treatment of myasthenia gravis to cure patients with myasthenia gravis. Provide a theoretical basis for the mechanism of action of MG patients with two-deficiency type
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Embodiment 1
[0055] Example 1 Preparation of Chinese Medicine Composition
[0056] 1. Accurate weighing the following weights of traditional Chinese medicine raw materials: 8 copies of Bahun, 10 Danshen, 5 copies, 20 parties, 20 Astragalus, 8 cases, 8 cases, Angelica 8 Majoron, 3 licorice, 3 tangerine peel, 6 枸杞, 12 yam, 12 pieces of chicken, 6 pieces of papaya, 15 pieces of medlar.
[0057] 2, pulverize the above Chinese medicine raw materials and mix well.
Embodiment 2
[0058] Example 2 Preparation of Chinese Medicine Composition
[0059] 1. Accurately weigh the following weights of Chinese medicine raw materials: 15 parts of Bahun, 24 Danshen, 10 in the Codonopsis, 160 copies of Astragalus, 30 Canton, 15 Attachment, 15 Heath, 6 licorice, 10 tonigons, 15 枸杞, 30 yam, 30 chickens, 15 papaya, 30 pieces of medlar.
[0060] 2, the above Chinese medicine is pulverized, milled, and the screen is made into fine powder, add water to cook 2 times, combined with decoction, concentrate, precipitate filtration, dry, and pulverize it.
Embodiment 3
[0061] Example 3 Preparation of Chinese Medicine Composition
[0062] 1, accurate weighing the following weights of Chinese medicine raw materials: Bahun Tianzhi, 15 Danskin, 40 Codonopsis, 85 Astragalus, 9 Chaiuri, Atractical Cantomi, Angelica 12 9 servants, 5 licorice, 5 tonigons, 10 枸杞, 25 yam, 25 chickens, 12 papaya, 20 pieces of 苓.
[0063] 2, the above Chinese medicine is pulverized, milled, and the sieve is made of fine powder. After stirring is uniform, the reflux of 5-10 times 80% ethanol is added twice, each time 1-2 hours, filtered, combined with refluxed fluid Concentrated into the cleanest, add water and decoction 2 times, combined with the decoction, concentrate into the cleans, dissolve the cleansted paste with 5-6 times the water, the upper large hole resin column, sequentially eluted with water and 40% ethanol The ethanol eluent is recovered, further concentrated into a thick paste, and pulverizes the powder.
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Technical field [0001] The present invention relates to the field of biopharmaceutical, and more relates to a Chinese medicine composition for treating severe and capable. Background technique [0002] Myasthenia Gravis (MG) is an autoimmune disease that is mainly involved in the acetylcholinereceptor, ACHR in the membrane of neuromuscular joints. The clinical is mainly manifested as partial or systemic skeletal muscleweakness and fatigue, and the symptoms of activities are aggravated, and the symptoms are reduced after treatment with CholinesinhiBitors, CHEI. Its pathogenesis has not been fully explicitly explicit. [0003] Chinese medicine has more spleen and stomach deficiency, spleen and kidneyyang deficiency, liver kidneyyin deficiency, meridian virtual damage. The spleen and stomach deficiencyists believe that MG 's etiology is mostly a spleen and stomach deficiency. Because of the spleen is "the book of the day", the stomach is "the sea of water valley", the spleen c...
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