Onychomycosis ointment and preparation method thereof

A technology of onychomycosis and ointment, which is applied in the field of medicine, can solve the problems of long healing time, large side effects, bleeding, etc., and achieve the effect of short healing time

Inactive Publication Date: 2018-09-14
陈雨薇
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to overcome the deficiencies in the prior art, provide a kind of onychomycosis ointment and preparation method thereof, to solve the large wound surface, bleeding, easy infection, long healing

Method used

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  • Onychomycosis ointment and preparation method thereof
  • Onychomycosis ointment and preparation method thereof
  • Onychomycosis ointment and preparation method thereof

Examples

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Example Embodiment

[0041] Example 1

[0042] Example 1 discloses a kind of onychomycosis ointment, including the following raw material components: garlic, ginger, Cnidium, Borneol, Artemisia argyi, Dafengzi, Touca, honey, salicylic acid, acetic acid solution, aloe gel and petrolatum;

[0043] Among them, the weight content of each raw material component is preferably:

[0044]

[0045] Wherein, the acetic acid solution is an acetic acid solution with a volume fraction of 30%.

[0046] This embodiment discloses a method for preparing the above onychomycosis ointment, including the following preparation steps:

[0047] Step 1. Weigh Cnidium, Dafengzi, and Borneol, mix and crush them, place them in a beaker, soak them in an ethanol solution with a mass concentration of 60% for 24 hours, and then transfer the soaked material to a three-necked flask for reflux heating. The reflux heating temperature in the three-necked flask was controlled at 75°C, and the reflux time was 2 hours; filtered and retained the f...

Example Embodiment

[0054] Example 2

[0055] Example 2 discloses a onychomycosis ointment, including the following raw material components: garlic, ginger, Cnidium, Borneol, Artemisia argyi, Dafengzi, Touca, honey, salicylic acid, acetic acid solution, aloe gel and petrolatum; Among them, the weight content of each raw material component is:

[0056]

[0057] Among them, the acetic acid solution is an acetic acid solution with a volume fraction of 35%.

[0058] This embodiment discloses a method for preparing the above onychomycosis ointment, including the following preparation steps:

[0059] Step 1. Weigh Cnidium, Dafengzi and Borneol, mix and crush them, place them in a beaker, soak them in an ethanol solution with a mass concentration of 65% for 24 hours, and then transfer the soaked material to a three-necked flask for reflux heating. The temperature of reflux heating in the three-necked flask was controlled at 80°C, and the reflux time was 2.5 hours; filtered and retained the filtrate to obtain t...

Example Embodiment

[0066] Example 3

[0067] Example 3 discloses a kind of onychomycosis ointment, including the following raw material components: garlic, ginger, Cnidium, Borneol, Artemisia argyi, Dafengzi, Tonicula, honey, salicylic acid, acetic acid solution, aloe gel and petrolatum; Among them, the weight content of each raw material component is:

[0068]

[0069] Wherein, the acetic acid solution is an acetic acid solution with a volume fraction of 45%.

[0070] This embodiment discloses a method for preparing the above onychomycosis ointment, including the following preparation steps:

[0071] Step 1. Weigh Cnidium, Dafengzi and Borneol, mix and crush them, place them in a beaker, soak them in an ethanol solution with a mass concentration of 75% for 24 hours, and then transfer the soaked material to a three-necked flask for reflux heating. The temperature of reflux heating in the three-necked flask was controlled at 85°C, and the reflux time was 3 hours; filtered and retained the filtrate to ob...

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Abstract

The invention discloses an onychomycosis ointment and a preparation method thereof. The preparation method comprises the following preparation steps: 1, pulverizing common cnidium fruits, chaulmoogratree seeds and borneol, and extracting a traditional Chinese medicine extracting solution I with an ethanol solution; 2, decocting and concentrating folium artemisiae argyi and garden balsam stem to obtain an aqueous extracting solution II; 3, pulverizing and juicing garlic cloves and ginger to obtain medicinal liquid III; 4, mixing and concentrating the traditional Chinese medicine extracting solution I, the aqueous extracting solution II and the medicinal liquid III, and adding salicylic acid and an acetate solution to obtain a traditional Chinese medicine mixture IV; 5, mixing honey with thetraditional Chinese medicine mixture IV to obtain an emulsion V; 6, mixing vaseline with aloe gel to obtain viscous liquid, and dropwise adding the viscous liquid to the emulsion V to obtain the onychomycosis ointment; and 7, performing high-pressure homogenization on the ointment to obtain a finished product of the onychomycosis ointment. The ointment prepared by the preparation method disclosedby the invention has the advantages that nails do not need to be excised through an operation, fungi in the onychomycosis can be killed only by smearing the ointment, and new nails can grow again; and the whole healing processes can not cause any pain, the healing time is short, no side effect is caused, relapse is avoided, and the treatment has no limitation for patients.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a nail fungus ointment and a preparation method thereof. Background technique [0002] Onychomycosis, commonly known as "onychomycosis", refers to a disease caused by dermatophytes invading the nail plate or under the nail. Onychomycosis is often caused by various fungi such as Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton flocculum. A few are caused by other filamentous fungi, yeast-like bacteria and saccharomyces, and occasionally it can also be caused by sporozoites, Fusarium and Aspergillus terrescens, etc., mostly seen in malnourished nails. The clinical manifestations are the following three types: 1. Subungual onychomycosis usually starts from both sides or ends of the deck, and there are mild paronychia first, and then gradually becomes chronic or gradually disappears. Paronychia can cause pits or grooves on the nail surface, which persist or gradually inv...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/06A61K47/06A61P17/00A61P31/10A61K31/045A61K35/644A61K31/60A61K31/19
CPCA61K9/0014A61K9/06A61K31/045A61K31/19A61K31/60A61K35/644A61K36/185A61K36/234A61K36/282A61K36/47A61K36/886A61K36/896A61K36/8962A61K36/9068A61K47/06A61K2236/331A61K2236/333A61K2236/39A61P17/00A61P31/10A61K2300/00
Inventor 陈雨薇
Owner 陈雨薇
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