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Heat-clearing anti-inflammatory traditional Chinese medicine composition

A composition and technology of traditional Chinese medicine, applied in the field of heat-clearing and anti-inflammatory traditional Chinese medicine compositions, can solve the problems of limiting the yield and utilization rate of shikimic acid, the extraction process is cumbersome and complicated, and the distribution of star anise is less, and achieves good economic benefits, simple process, raw material High utilization effect

Inactive Publication Date: 2018-10-26
南宁市黄陈生猪养殖场
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, the main way to obtain shikimic acid is to extract it from plants. The main raw material is star anise. Production and Utilization of Oxalic Acid

Method used

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  • Heat-clearing anti-inflammatory traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] (1) Ginkgo biloba leaves were dried at 60°C, crushed and passed through a 60-mesh sieve, added water according to the material-to-water ratio of 1:20, extracted in a water bath at 80°C for 3 hours, and then centrifuged at 2000 rpm to remove the residue after cooling to room temperature. get the extract;

[0033] (2) Heat and concentrate the extract to 0.5 times the original volume, inoculate 1% rum yeast, and ferment for 6 days under anaerobic conditions at 30°C to obtain a fermentation broth;

[0034] (3) Add β-cyclodextrin solution with a mass concentration of 0.5% to the fermentation broth, and mix evenly to obtain the mixed solution 1, which is pasteurized for 50 minutes to obtain the mixed solution 2;

[0035] The volume ratio of the fermented broth and the β-cyclodextrin solution is 1:45;

[0036] (4) Add 1% activated carbon by volume to the mixture 2, decolorize at 70°C for 50 minutes, remove the activated carbon by filtration, and obtain a crude extract;

[00...

Embodiment 2

[0044] (1) Take liquidambar leaves and dry them at 60°C, crush them through an 80-mesh sieve, add water according to the material-to-water ratio of 1:30, extract in a water bath at 100°C for 4 hours, and centrifuge at 3000rpm to remove the residue after cooling to room temperature , to obtain the extract;

[0045] (2) Heat and concentrate the extract to 0.6 times the original volume, inoculate 3% rum yeast, and ferment for 8 days under anaerobic conditions at 35°C to obtain a fermentation broth;

[0046] (3) Add β-cyclodextrin solution with a mass concentration of 0.5% to the fermentation broth, mix evenly to obtain the mixed solution 1, and pasteurize it for 60 minutes to obtain the mixed solution 2;

[0047] The volume ratio of the fermented broth to the β-cyclodextrin solution is 1:55;

[0048] (4) Add 1.5% activated carbon by volume to the mixed liquid 2, decolorize at 80°C for 60 minutes, remove the activated carbon by filtration, and obtain a crude extract;

[0049] (5...

Embodiment 3

[0056] (1) Take lemon eucalyptus leaves and dry them at 60°C, crush them through a 70-mesh sieve, add water according to the material-to-water ratio of 1:25, extract in a water bath at 90°C for 4 hours, and centrifuge at 3000 rpm to remove the residue after cooling to room temperature , to obtain the extract;

[0057] (2) Heat and concentrate the extract to 0.6 times the original volume, inoculate 2% rum yeast, and ferment for 7 days under anaerobic conditions at 32°C to obtain a fermentation broth;

[0058] (3) Add β-cyclodextrin solution with a mass concentration of 0.5% to the fermentation broth, mix evenly to obtain the mixed solution 1, and pasteurize it for 60 minutes to obtain the mixed solution 2;

[0059] The volume ratio of the fermentation broth and the β-cyclodextrin solution is 1:50;

[0060] (4) Add 1.3% activated carbon by volume to the mixture 2, decolorize at 75°C for 60 minutes, remove the activated carbon by filtration, and obtain a crude extract;

[0061]...

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Abstract

The invention provides a heat-clearing anti-inflammatory traditional Chinese medicine composition. The heat-clearing anti-inflammatory traditional Chinese medicine composition is prepared from shikimic acid, lysimachia christinae hance, liquorice and borneol. The shikimic acid is extracted from natural substances such as anise, deodar, folium ginkgo, needles of pinus massoniana, folium liquidambaris and lemon eucalyptus leaves, and is prepared by the following steps: grinding the raw materials, and performing crude extraction with water; inoculating into liqueur koji for fermenting, and decomposing the raw materials into glucose by utilizing rhizopus and hairy molds; performing sugar fermentation on the yeasts to produce ethanol; and finally adding a beta-cyclodextrin solution and fermentation product alcohol to perform secondary extraction together, discoloring, filtering and crystallizing, thereby obtaining the shikimic acid. According to the heat-clearing anti-inflammatory traditional Chinese medicine composition disclosed by the invention, more resources are provided for the source of the shikimic acid, the extraction process is simple, the raw material utilization rate is high, and more sources are provided for preparation of heat-clearing anti-inflammatory drugs.

Description

technical field [0001] The invention belongs to the technical field of preparation of traditional Chinese medicines, in particular to a heat-clearing and anti-inflammatory traditional Chinese medicine composition. Background technique [0002] Anemopyretic cold is caused by the appearance of wind-heat evil criminals and loss of lung energy. Symptoms include severe fever, mild wind, head bloating, sweating, sore throat, cough, sticky or yellow phlegm, yellow stuffy nose, thirsty drink, red tip of tongue, thin white yellowish fur. Wind-heat cold is more common in summer and autumn, caused by exogenous wind-heat. According to traditional Chinese medicine, wind-heat cold is the superficial syndrome caused by feeling the evil of wind-heat. Syndrome: fever without sweating, or poor sweating, slight aversion to wind and cold, headache and thirst, cough and sore throat, red tip of tongue, thin white or yellow fur, floating and rapid pulse. Therapeutic Principles: The treatment of...

Claims

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Application Information

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IPC IPC(8): A61K36/484A61K36/53A61P29/00A61K31/19A61K31/045
CPCA61K31/19A61K31/045A61K36/185A61K36/484A61K36/53A61K2236/19A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2236/55A61P29/00A61K2300/00
Inventor 黄陈玉
Owner 南宁市黄陈生猪养殖场
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