Traditional Chinese medicine composition for treating AIDS (acquired immune deficiency syndrome) as well as preparation method and application thereof

A composition and AIDS technology, applied in the field of medicines for the treatment of AIDS and traditional Chinese medicine compositions for the treatment of AIDS, can solve the problems of insufficient curative effect, poor curative effect and high degree of pain, achieve exact recovery or treatment efficacy, and improve self-healing ability , reduce the effect of HIV virus

Inactive Publication Date: 2018-11-02
王时栋 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Combination antiretroviral therapy (i.e. cocktail therapy) is currently recognized as the most effective treatment to suppress the disease and prolong life, but its treatment costs are very expensive, and few patients can afford the huge treatment costs. In addition, this method still exists Toxic and side effects and other defects, the patient reacts strongly after taking the medicine, and the degree of pain is high, and the patient needs to reach a certain physical condition before using this therapy, and generally needs to take medicine for life
[0004] The existing anti-HIV chemical drugs are mainly western medicines (such as nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors and protease inhibitors), which have poor curative effect, large toxic and side effects, low oral availability, High cost and other disadvantages, so it is urgent to find new anti-HIV drugs with high efficiency, low toxicity and low price
Although the existing traditional Chinese medicine compositions for the treatment of AIDS have certain curative effects on AIDS, they all have defects such as insufficient curative effect and low safety to varying degrees, which need to be improved urgently.

Method used

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  • Traditional Chinese medicine composition for treating AIDS (acquired immune deficiency syndrome) as well as preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] The preparation of embodiment 1 granule

[0048] (1) Take each crude drug by the following weight: (unit: g): Fritillaria 45, Polygonum cuspidatum 25, Gentiana 25, Areca nut 10, Alum 2, Honey 1;

[0049] (2) Add water to decoct each raw material twice, add 8 times the weight of water for the first time, decoct for 2 hours, filter to obtain the filtrate; add 7 times the weight of water to the dregs, decoct for 1.5 hours, filter , to obtain the filtrate; combine the filtrate;

[0050] (3) The filtrate obtained in step (2) is concentrated to an extract whose relative density is 1.12-1.18 (75°C), spray-dried to obtain a dry extract powder;

[0051] (4) Add an appropriate amount of starch to the dry extract powder and mix it, dry press it into granules, then add an appropriate amount of dextrin, mix evenly, subpackage, and pack to obtain the finished product.

Embodiment 2

[0052] The preparation of embodiment 2 granules

[0053] (1) Take each crude drug by the following weight: (unit: g): Fritillaria 65, Polygonum cuspidatum 40, Gentiana 35, Areca nut 20, Alum 8, Honey 6;

[0054] (2) Each raw material is decocted twice with water, adding 10 times the weight of water for the first time, decocting for 2 hours, filtering to obtain the filtrate; adding 8 times the weight of water to the dregs, decocting for 1.5 hours, filtering , to obtain the filtrate; combine the filtrate;

[0055] (3) The filtrate obtained in step (2) is concentrated to an extract whose relative density is 1.12-1.18 (75°C), spray-dried to obtain a dry extract powder;

[0056] (4) Add an appropriate amount of starch to the dry extract powder and mix it, dry press it into granules, then add an appropriate amount of dextrin, mix evenly, subpackage, and pack to obtain the finished product.

Embodiment 3

[0057] The preparation of embodiment 3 granules

[0058] (1) Take each crude drug by the following weight: (unit: g): Fritillaria 50, Polygonum cuspidatum 35, Gentiana 30, Areca nut 15, Alum 6, Honey 4;

[0059] (2) Each raw material drug is decocted twice with water, adding 7 times the weight of water for the first time, decocting for 2 hours, filtering to obtain the filtrate; adding 8 times the weight of water to the dregs, decocting for 1.5 hours, filtering , to obtain the filtrate; combine the filtrate;

[0060] (3) The filtrate obtained in step (2) is concentrated to an extract whose relative density is 1.12-1.18 (75°C), spray-dried to obtain a dry extract powder;

[0061] (4) Add an appropriate amount of starch to the dry extract powder and mix it, dry press it into granules, then add an appropriate amount of dextrin, mix evenly, subpackage, and pack to obtain the finished product.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating AIDS (acquired immune deficiency syndrome) as well as a preparation method and application thereof; the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 45-65 parts of bulb of fritillary, 25-40 parts of rhizoma polygontum cuspidatum, 25-35 parts of radix geutianae, 10-20 parts of betel nuts, 2-8 parts of white alum, 1-6 parts of bee honey, 4-10 parts of radix lithospermi, 2-8 parts of nidus vespae, 10-20 parts of herba artemisiae capillariae, 8-15 parts of fructus forsythiae and 8-15 parts of radix isatidis. According to the invention, Chinese herbal medicines against different targets of HIV viruses are screened respectively for the immune function lossof AIDS patients, and combined together to maximize the effectiveness, so that the self-healing ability of patients is effectively improved, the number of T lymphocytes in the AIDS patients is significantly increased, the HIV viral load in a body is smaller than 20 cp/m, and the immunity of the patients is significantly improved; and the traditional Chinese medicine composition has a definite effect of restoring liver and kidney function damage in the AIDS patients. The traditional Chinese medicine composition is safe in clinical application and has no toxic or side effects.

Description

technical field [0001] The invention relates to a medicine for treating AIDS, in particular to a Chinese medicine composition for treating AIDS. The invention further relates to a preparation method of the Chinese medicine composition and its application in treating AIDS, which belong to the field of Chinese medicine treatment of AIDS. Background technique [0002] AIDS (AIDS) is also called Acquired Immunodeficiency Syndrome. Caused by human immunodeficiency virus (HIV-human immunodeficiency virus), AIDS virus is divided into two types: HIV-1 and HIV-2, and they have their own subtypes. Different subtypes are prevalent in different regions, and the same subtype also has certain differences in different regions. The HIV virus is latent and combined with human cells. Once it starts to multiply, it will cause serious casualties to the patient's T helper lymphocytes, resulting in a decline in immunity, which in turn will promote a series of related diseases. [0003] So far, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61P31/18A61P1/16A61P13/12A61K35/644A61K33/06A61K35/64
CPCA61K36/8966A61K33/06A61K35/63A61K35/644A61K36/195A61K36/282A61K36/30A61K36/315A61K36/515A61K36/634A61K36/704A61K36/889A61K2236/331A61K2236/51A61K2300/00
Inventor 王时栋杨文有
Owner 王时栋
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