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Medicinal food used for alleviating or eliminating cancer related fatigue and preparation method thereof

A technology of medicated diet and yam, which is applied in the direction of medical formula, medical preparations containing active ingredients, drug combination, etc., can solve the problems of easy change of biological activity of medicated diet, poor taste, complicated extraction process, etc.

Inactive Publication Date: 2018-11-23
HUNAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] The technical problem solved by the present invention is that the extraction process of the existing similar medicated diet is complex, the biological activity of the medicated diet is easily changed, and the taste is poor, etc.

Method used

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  • Medicinal food used for alleviating or eliminating cancer related fatigue and preparation method thereof
  • Medicinal food used for alleviating or eliminating cancer related fatigue and preparation method thereof
  • Medicinal food used for alleviating or eliminating cancer related fatigue and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] 1 Instruments and materials

[0055] 1.1 Instrument

[0056] Ultimate 3000 High Performance Liquid Chromatography System (Thermo Fisher Scientific (China) Co., Ltd.; including G1316A Quaternary Gradient Pump, G1313A Standard Autosampler, G1316A Thermostat, G1314A UV Detector, AgilentChemstation Chromatographic Workstation); UV9100B UV-visible spectrophotometer (Beijing Labtech Instrument Co., Ltd.); YP-B5001 electronic balance (Shanghai Guangzheng Yiyuan Instrument Co., Ltd.); RHP-400 high-speed multifunctional pulverizer (Zhejiang Yongkang Ronghao Industrial Co., Ltd. company); SHH.W21 electronic three-water tank (Beijing Zhongxing Weiye Instrument Co., Ltd.); SHB-Ⅲ circulating water multi-purpose vacuum pump (Zhengzhou Changcheng Technology Industry and Trade Co., Ltd.); YJD20 old pharmacist room temperature decoction machine (Changsha Zhuocheng Medical Instrument Co., Ltd.); RE-200013 rotary evaporator (Gongyi Yuhua Instrument Co., Ltd.).

[0057] 1.2 Medicinal mat...

Embodiment 2

[0118] Example 2: Acute Oral Toxicity Test of Seabuckthorn Guben Instant Tea

[0119] In this study, ICR mice were given the test samples by oral gavage, and observed continuously for 14 days. From the results of the acute toxicity test of the mice, we can know whether the test samples are toxic, as well as the degree of toxic reactions and the organs involved. The dosage design, the selection of toxic reaction indicators and the development of clinical trials provide experimental basis.

[0120] 1. Experimental materials

[0121] 1.1 Test sample

[0122] Seabuckthorn Guben Instant Tea, batch number: 20180123, dark brown solid particles, easily soluble in water, each gram of sample is equivalent to 2.36g of the original medicinal material. The recommended dosage for adults is 2.0g / time, 2 times / day, mixed with boiling water, provided by Hunan University of Traditional Chinese Medicine, stored in a low-temperature and dry environment, avoiding direct sunlight.

[0123] 1.2 E...

Embodiment 3

[0149] Example 3: Inhibitory effect of seabuckthorn Guben instant tea on human gastric cancer cell MGC803 cultured in vitro

[0150] 1. Materials and Methods

[0151] 1.1 Materials

[0152] 1.1.1 Human gastric cancer epithelial MGC803 cells were purchased from the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences

[0153] 1.1.2 Drugs and reagents Preparation of total component solution of seabuckthorn Guben instant tea Chinese medicine: Weigh a certain amount of total component of seabuckthorn Guben instant tea Chinese medicine, dissolve it in complete culture medium to prepare the concentration required for the experiment, and use 0.45 μm, Sterilize with a 0.22 μm disposable filter and store at 4°C for later use. When in use, dilute the mother liquor of the total components of the seabuckthorn Guben instant tea traditional Chinese medicine with the pre-warmed complete culture solution to the concentration required for the experiment.

[0154] 1.2 Cel...

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Abstract

The invention discloses medicinal food used for alleviating or eliminating cancer related fatigue and a preparation method thereof. The medicinal food is prepared from the following raw materials: 8-12 g of ginseng, 12-18 g of poria, 3-7 g of prepared radix licorice, 20-30 g of yam, 3-7 g of hawthorn, 3-7 g of tangerine peel, 12-18 g of fructus lycii, 20-30 g of rhizoma polygonatum and 16-24 g ofhippophae rhamnosides. According to the medicinal food used for alleviating or eliminating cancer related fatigue and the preparation method thereof, sijunzi decoction is used as a base for conductingadding and subtracting and is cooperation with the medicinal and edible food hippophae rhamnosides, starting with congenital and acquired constitution foundations, an overall balance state of a bodyis recovered, the advantages of traditional Chinese medicine medicinal food and a modern beverage production technology are combined, a traditional Chinese medicine medicinal food theory, the modern food nutrition and hygiene and the food technology are applied as guides, the medicines are used in the food, not only are the medicines used for the food, but also the food is endowed with medicinal use, the medicines draw on the power of the food, the food enhances the strength of the medicines, and the food and the medicine supplement and complement each other.

Description

technical field [0001] The invention relates to a medicated diet for alleviating or eliminating cancer-related fatigue and a preparation method thereof. Background technique [0002] With the changes of the times, social patterns, changes in behavior habits, environmental pollution, junk food and other adverse factors have increased, resulting in a rapid increase in the incidence and mortality of malignant tumors worldwide in recent decades. The incidence and mortality of malignant tumors in my country have also increased significantly. In 2014, the number of cancer deaths was about 2.21 million, accounting for 22.4% of the national mortality rate. Tumors have gradually become a major threat to human health. People's awareness of the crisis of tumors is getting higher and higher, and the treatment methods are also showing a trend of diversification. With the development of modern science and technology and the rapid improvement of medical methods, the life cycle of cancer p...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P35/00
CPCA61K36/076A61K36/185A61K36/258A61K36/484A61K36/734A61K36/752A61K36/815A61K36/8945A61K36/8969A61K2236/331A61K2236/39A61K2236/51A61P35/00A61K2300/00
Inventor 谢梦洲宋毓涛王亚敏张超文陈光宇瞿昊宇
Owner HUNAN UNIV OF CHINESE MEDICINE
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